TAOK1: Difference between revisions

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{{Infobox_gene}}
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'''Serine/threonine-protein kinase TAO1''' is an [[enzyme]] that in humans is encoded by the ''TAOK1'' [[gene]].<ref name="pmid10718198">{{cite journal | vauthors = Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res | volume = 7 | issue = 1 | pages = 65–73 |date=Apr 2000 | pmid = 10718198 | pmc =  | doi =10.1093/dnares/7.1.65 }}</ref><ref name="pmid14517247">{{cite journal | vauthors = Timm T, Li XY, Biernat J, Jiao J, Mandelkow E, Vandekerckhove J, Mandelkow EM | title = MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1 | journal = EMBO J | volume = 22 | issue = 19 | pages = 5090–101 |date=Sep 2003 | pmid = 14517247 | pmc = 204455 | doi = 10.1093/emboj/cdg447 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TAOK1 TAO kinase 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57551| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = TAO kinase 1
| HGNCid = 29259
| Symbol = TAOK1
| AltSymbols =; FLJ14314; KIAA1361; MAP3K16; MARKK; PSK2
| OMIM = 610266
| ECnumber =
| Homologene = 27041
| MGIid = 1914490
  | GeneAtlas_image1 = PBB_GE_TAOK1_gnf1h10610_at_tn.png
  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0004674 |text = protein serine/threonine kinase activity}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0016740 |text = transferase activity}}
| Component =
| Process = {{GNF_GO|id=GO:0006468 |text = protein amino acid phosphorylation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 57551
    | Hs_Ensembl = ENSG00000160551
    | Hs_RefseqProtein = NP_065842
    | Hs_RefseqmRNA = NM_020791
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 24742069
    | Hs_GenLoc_end = 24895628
    | Hs_Uniprot = Q7L7X3
    | Mm_EntrezGene = 216965
    | Mm_Ensembl = ENSMUSG00000017291
    | Mm_RefseqmRNA = XM_001001182
    | Mm_RefseqProtein = XP_001001182
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 77353793
    | Mm_GenLoc_end = 77401644
    | Mm_Uniprot = Q3UUG1
  }}
}}
'''TAO kinase 1''', also known as '''TAOK1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TAOK1 TAO kinase 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57551| accessdate = }}</ref>
 
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Hutchison M, Berman KS, Cobb MH |title=Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades. |journal=J. Biol. Chem. |volume=273 |issue= 44 |pages= 28625-32 |year= 1998 |pmid= 9786855 |doi=  }}
*{{cite journal  | vauthors=Hutchison M, Berman KS, Cobb MH |title=Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades |journal=J. Biol. Chem. |volume=273 |issue= 44 |pages= 28625–32 |year= 1998 |pmid= 9786855 |doi=10.1074/jbc.273.44.28625 }}
*{{cite journal  | author=Chen Z, Hutchison M, Cobb MH |title=Isolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase binding domain. |journal=J. Biol. Chem. |volume=274 |issue= 40 |pages= 28803-7 |year= 1999 |pmid= 10497253 |doi= }}
*{{cite journal  | vauthors=Chen Z, Hutchison M, Cobb MH |title=Isolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase binding domain |journal=J. Biol. Chem. |volume=274 |issue= 40 |pages= 28803–7 |year= 1999 |pmid= 10497253 |doi=10.1074/jbc.274.40.28803 }}
*{{cite journal  | author=Nagase T, Kikuno R, Ishikawa KI, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 1 |pages= 65-73 |year= 2000 |pmid= 10718198 |doi= }}
*{{cite journal   |vauthors=Dias Neto E, Correa RG, Verjovski-Almeida S, etal |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491–6 |year= 2000 |pmid= 10737800 |doi=10.1073/pnas.97.7.3491  | pmc=16267 }}
*{{cite journal | author=Dias Neto E, Correa RG, Verjovski-Almeida S, ''et al.'' |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491-6 |year= 2000 |pmid= 10737800 |doi=  }}
*{{cite journal   |vauthors=Wistow G, Bernstein SL, Wyatt MK, etal |title=Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants |journal=Mol. Vis. |volume=8 |issue=  |pages= 205–20 |year= 2002 |pmid= 12107410 |doi=  }}
*{{cite journal | author=Wistow G, Bernstein SL, Wyatt MK, ''et al.'' |title=Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. |journal=Mol. Vis. |volume=8 |issue=  |pages= 205-20 |year= 2002 |pmid= 12107410 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Yustein JT, Xia L, Kahlenburg JM, etal |title=Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38 |journal=Oncogene |volume=22 |issue= 40 |pages= 6129–41 |year= 2003 |pmid= 13679851 |doi= 10.1038/sj.onc.1206605 }}
*{{cite journal | author=Yustein JT, Xia L, Kahlenburg JM, ''et al.'' |title=Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38. |journal=Oncogene |volume=22 |issue= 40 |pages= 6129-41 |year= 2003 |pmid= 13679851 |doi= 10.1038/sj.onc.1206605 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Timm T, Li XY, Biernat J, ''et al.'' |title=MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1. |journal=EMBO J. |volume=22 |issue= 19 |pages= 5090-101 |year= 2003 |pmid= 14517247 |doi= 10.1093/emboj/cdg447 }}
*{{cite journal   |vauthors=Lizcano JM, Göransson O, Toth R, etal |title=LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1 |journal=EMBO J. |volume=23 |issue= 4 |pages= 833–43 |year= 2005 |pmid= 14976552 |doi= 10.1038/sj.emboj.7600110 | pmc=381014 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 }}
*{{cite journal | author=Lizcano JM, Göransson O, Toth R, ''et al.'' |title=LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. |journal=EMBO J. |volume=23 |issue= 4 |pages= 833-43 |year= 2005 |pmid= 14976552 |doi= 10.1038/sj.emboj.7600110 }}
*{{cite journal   |vauthors=Zihni C, Mitsopoulos C, Tavares IA, etal |title=Prostate-derived sterile 20-like kinase 2 (PSK2) regulates apoptotic morphology via C-Jun N-terminal kinase and Rho kinase-1 |journal=J. Biol. Chem. |volume=281 |issue= 11 |pages= 7317–23 |year= 2006 |pmid= 16407310 |doi= 10.1074/jbc.M513769200 }}
*{{cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
*{{cite journal   |vauthors=Beausoleil SA, Villén J, Gerber SA, etal |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
*{{cite journal | author=Zihni C, Mitsopoulos C, Tavares IA, ''et al.'' |title=Prostate-derived sterile 20-like kinase 2 (PSK2) regulates apoptotic morphology via C-Jun N-terminal kinase and Rho kinase-1. |journal=J. Biol. Chem. |volume=281 |issue= 11 |pages= 7317-23 |year= 2006 |pmid= 16407310 |doi= 10.1074/jbc.M513769200 }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Beausoleil SA, Villén J, Gerber SA, ''et al.'' |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285-92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
*{{cite journal   |vauthors=Raman M, Earnest S, Zhang K, etal |title=TAO kinases mediate activation of p38 in response to DNA damage |journal=EMBO J. |volume=26 |issue= 8 |pages= 2005–14 |year= 2007 |pmid= 17396146 |doi= 10.1038/sj.emboj.7601668 | pmc=1852793 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal   |vauthors=Draviam VM, Stegmeier F, Nalepa G, etal |title=A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling |journal=Nat. Cell Biol. |volume=9 |issue= 5 |pages= 556–64 |year= 2007 |pmid= 17417629 |doi= 10.1038/ncb1569 }}
*{{cite journal | author=Raman M, Earnest S, Zhang K, ''et al.'' |title=TAO kinases mediate activation of p38 in response to DNA damage. |journal=EMBO J. |volume=26 |issue= 8 |pages= 2005-14 |year= 2007 |pmid= 17396146 |doi= 10.1038/sj.emboj.7601668 }}
*{{cite journal | author=Draviam VM, Stegmeier F, Nalepa G, ''et al.'' |title=A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling. |journal=Nat. Cell Biol. |volume=9 |issue= 5 |pages= 556-64 |year= 2007 |pmid= 17417629 |doi= 10.1038/ncb1569 }}
}}
}}
{{refend}}
{{refend}}


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Revision as of 11:33, 15 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Serine/threonine-protein kinase TAO1 is an enzyme that in humans is encoded by the TAOK1 gene.[1][2][3]


References

  1. ↑ Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
  2. ↑ Timm T, Li XY, Biernat J, Jiao J, Mandelkow E, Vandekerckhove J, Mandelkow EM (Sep 2003). "MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1". EMBO J. 22 (19): 5090–101. doi:10.1093/emboj/cdg447. PMC 204455. PMID 14517247.
  3. ↑ "Entrez Gene: TAOK1 TAO kinase 1".

Further reading



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