PLA2G4B: Difference between revisions

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'''Phospholipase A2, group IVB (cytosolic)''', also known as '''PLA2G4B''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PLA2G4B phospholipase A2, group IVB (cytosolic)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8681| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Phospholipase A2, group IVB (cytosolic)
| HGNCid = 9036
| Symbol = PLA2G4B
| AltSymbols =; FLJ42498; HsT16992; cPLA2-beta
| OMIM = 606088
| ECnumber = 
| Homologene = 3730
| MGIid = 2384819
| GeneAtlas_image1 = PBB_GE_PLA2G4B_60528_at_tn.png
| GeneAtlas_image2 = PBB_GE_PLA2G4B_219095_at_tn.png
| GeneAtlas_image3 = PBB_GE_PLA2G4B_222256_s_at_tn.png
| Function = {{GNF_GO|id=GO:0004622 |text = lysophospholipase activity}} {{GNF_GO|id=GO:0005509 |text = calcium ion binding}} {{GNF_GO|id=GO:0005544 |text = calcium-dependent phospholipid binding}} {{GNF_GO|id=GO:0016787 |text = hydrolase activity}} {{GNF_GO|id=GO:0047498 |text = calcium-dependent phospholipase A2 activity}}  
| Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0005829 |text = cytosol}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0006954 |text = inflammatory response}} {{GNF_GO|id=GO:0007567 |text = parturition}} {{GNF_GO|id=GO:0016042 |text = lipid catabolic process}} {{GNF_GO|id=GO:0019369 |text = arachidonic acid metabolic process}} {{GNF_GO|id=GO:0019722 |text = calcium-mediated signaling}} {{GNF_GO|id=GO:0046475 |text = glycerophospholipid catabolic process}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 8681
    | Hs_Ensembl = ENSG00000168970
    | Hs_RefseqProtein = NP_005081
    | Hs_RefseqmRNA = NM_005090
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 15
    | Hs_GenLoc_start = 39907603
    | Hs_GenLoc_end = 39927637
    | Hs_Uniprot = O95712
    | Mm_EntrezGene = 211429
    | Mm_Ensembl = ENSMUSG00000033852
    | Mm_RefseqmRNA = XM_355378
    | Mm_RefseqProtein = XP_355378
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 119718947
    | Mm_GenLoc_end = 119734471
    | Mm_Uniprot = Q06G06
  }}
}}
'''Phospholipase A2, group IVB (cytosolic)''', also known as '''PLA2G4B''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PLA2G4B phospholipase A2, group IVB (cytosolic)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8681| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Schröder HC, Perovic S, Kavsan V, ''et al.'' |title=Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death. |journal=Neurotoxicology |volume=19 |issue= 4-5 |pages= 683-8 |year= 1998 |pmid= 9745929 |doi=  }}
*{{cite journal   |vauthors=Schröder HC, Perovic S, Kavsan V, etal |title=Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death. |journal=Neurotoxicology |volume=19 |issue= 4–5 |pages= 683–8 |year= 1998 |pmid= 9745929 |doi=  }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=  }}
*{{cite journal  | vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Mavoungou E, Georges-Courbot MC, Poaty-Mavoungou V, ''et al.'' |title=HIV and SIV envelope glycoproteins induce phospholipase A2 activation in human and macaque lymphocytes. |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=16 |issue= 1 |pages= 1-9 |year= 1997 |pmid= 9377118 |doi=  }}
*{{cite journal   |vauthors=Mavoungou E, Georges-Courbot MC, Poaty-Mavoungou V, etal |title=HIV and SIV envelope glycoproteins induce phospholipase A2 activation in human and macaque lymphocytes |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=16 |issue= 1 |pages= 1–9 |year= 1997 |pmid= 9377118 |doi=  10.1097/00042560-199709010-00001}}
*{{cite journal | author=Underwood KW, Song C, Kriz RW, ''et al.'' |title=A novel calcium-independent phospholipase A2, cPLA2-gamma, that is prenylated and contains homology to cPLA2. |journal=J. Biol. Chem. |volume=273 |issue= 34 |pages= 21926-32 |year= 1998 |pmid= 9705332 |doi=  }}
*{{cite journal   |vauthors=Underwood KW, Song C, Kriz RW, etal |title=A novel calcium-independent phospholipase A2, cPLA2-gamma, that is prenylated and contains homology to cPLA2 |journal=J. Biol. Chem. |volume=273 |issue= 34 |pages= 21926–32 |year= 1998 |pmid= 9705332 |doi=10.1074/jbc.273.34.21926 }}
*{{cite journal  | author=Pickard RT, Strifler BA, Kramer RM, Sharp JD |title=Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2. |journal=J. Biol. Chem. |volume=274 |issue= 13 |pages= 8823-31 |year= 1999 |pmid= 10085124 |doi=  }}
*{{cite journal  | vauthors=Pickard RT, Strifler BA, Kramer RM, Sharp JD |title=Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2 |journal=J. Biol. Chem. |volume=274 |issue= 13 |pages= 8823–31 |year= 1999 |pmid= 10085124 |doi=10.1074/jbc.274.13.8823 }}
*{{cite journal | author=Song C, Chang XJ, Bean KM, ''et al.'' |title=Molecular characterization of cytosolic phospholipase A2-beta. |journal=J. Biol. Chem. |volume=274 |issue= 24 |pages= 17063-7 |year= 1999 |pmid= 10358058 |doi=  }}
*{{cite journal   |vauthors=Song C, Chang XJ, Bean KM, etal |title=Molecular characterization of cytosolic phospholipase A2-beta |journal=J. Biol. Chem. |volume=274 |issue= 24 |pages= 17063–7 |year= 1999 |pmid= 10358058 |doi=10.1074/jbc.274.24.17063 }}
*{{cite journal | author=Degousee N, Ghomashchi F, Stefanski E, ''et al.'' |title=Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis. |journal=J. Biol. Chem. |volume=277 |issue= 7 |pages= 5061-73 |year= 2002 |pmid= 11741884 |doi= 10.1074/jbc.M109083200 }}
*{{cite journal   |vauthors=Degousee N, Ghomashchi F, Stefanski E, etal |title=Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis |journal=J. Biol. Chem. |volume=277 |issue= 7 |pages= 5061–73 |year= 2002 |pmid= 11741884 |doi= 10.1074/jbc.M109083200 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal  | author=Pope SN, Lee IR |title=Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin. |journal=J. Steroid Biochem. Mol. Biol. |volume=94 |issue= 1-3 |pages= 203-8 |year= 2005 |pmid= 15862967 |doi= 10.1016/j.jsbmb.2005.01.007 }}
*{{cite journal  | vauthors=Pope SN, Lee IR |title=Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin |journal=J. Steroid Biochem. Mol. Biol. |volume=94 |issue= 1–3 |pages= 203–8 |year= 2005 |pmid= 15862967 |doi= 10.1016/j.jsbmb.2005.01.007 }}
*{{cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
*{{cite journal  | author=Ghosh M, Loper R, Gelb MH, Leslie CC |title=Identification of the expressed form of human cytosolic phospholipase A2beta (cPLA2beta): cPLA2beta3 is a novel variant localized to mitochondria and early endosomes. |journal=J. Biol. Chem. |volume=281 |issue= 24 |pages= 16615-24 |year= 2006 |pmid= 16617059 |doi= 10.1074/jbc.M601770200 }}
*{{cite journal  | vauthors=Ghosh M, Loper R, Gelb MH, Leslie CC |title=Identification of the expressed form of human cytosolic phospholipase A2beta (cPLA2beta): cPLA2beta3 is a novel variant localized to mitochondria and early endosomes |journal=J. Biol. Chem. |volume=281 |issue= 24 |pages= 16615–24 |year= 2006 |pmid= 16617059 |doi= 10.1074/jbc.M601770200 }}
}}
}}
{{refend}}
{{refend}}


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Revision as of 18:15, 7 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Phospholipase A2, group IVB (cytosolic), also known as PLA2G4B, is a human gene.[1]


References

  1. ↑ "Entrez Gene: PLA2G4B phospholipase A2, group IVB (cytosolic)".

Further reading



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