SUV39H2: Difference between revisions

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'''Histone-lysine N-methyltransferase SUV39H2''' is an [[enzyme]] that in humans is encoded by the ''SUV39H2'' [[gene]].<ref name="pmid11094092">{{cite journal | vauthors = O'Carroll D, Scherthan H, Peters AH, Opravil S, Haynes AR, Laible G, Rea S, Schmid M, Lebersorger A, Jerratsch M, Sattler L, Mattei MG, Denny P, Brown SD, Schweizer D, Jenuwein T | title = Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression | journal = Mol Cell Biol | volume = 20 | issue = 24 | pages = 9423–33 |date=Dec 2000 | pmid = 11094092 | pmc = 102198 | doi =10.1128/MCB.20.24.9423-9433.2000 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79723| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Suppressor of variegation 3-9 homolog 2 (Drosophila)
| HGNCid = 17287
| Symbol = SUV39H2
| AltSymbols =; FLJ23414
| OMIM = 606503
| ECnumber = 
| Homologene = 32548
| MGIid = 1890396
| GeneAtlas_image1 = PBB_GE_SUV39H2_219262_at_tn.png
| Function = {{GNF_GO|id=GO:0003682 |text = chromatin binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0008276 |text = protein methyltransferase activity}} {{GNF_GO|id=GO:0016740 |text = transferase activity}} {{GNF_GO|id=GO:0046974 |text = histone lysine N-methyltransferase activity (H3-K9 specific)}}
| Component = {{GNF_GO|id=GO:0000785 |text = chromatin}} {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005720 |text = nuclear heterochromatin}}
| Process = {{GNF_GO|id=GO:0006333 |text = chromatin assembly or disassembly}} {{GNF_GO|id=GO:0006338 |text = chromatin remodeling}} {{GNF_GO|id=GO:0007140 |text = male meiosis}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 79723
    | Hs_Ensembl = ENSG00000152455
    | Hs_RefseqProtein = NP_078946
    | Hs_RefseqmRNA = NM_024670
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 10
    | Hs_GenLoc_start = 14960825
    | Hs_GenLoc_end = 14986320
    | Hs_Uniprot = Q9H5I1
    | Mm_EntrezGene = 64707
    | Mm_Ensembl = ENSMUSG00000026646
    | Mm_RefseqmRNA = NM_022724
    | Mm_RefseqProtein = NP_073561
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 3373092
    | Mm_GenLoc_end = 3392236
    | Mm_Uniprot = Q8BNK2
  }}
}}
'''Suppressor of variegation 3-9 homolog 2 (Drosophila)''', also known as '''SUV39H2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79723| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Rea S, Eisenhaber F, O'Carroll D, ''et al.'' |title=Regulation of chromatin structure by site-specific histone H3 methyltransferases. |journal=Nature |volume=406 |issue= 6796 |pages= 593-9 |year= 2000 |pmid= 10949293 |doi= 10.1038/35020506 }}
*{{cite journal   |vauthors=Rea S, Eisenhaber F, O'Carroll D, etal |title=Regulation of chromatin structure by site-specific histone H3 methyltransferases |journal=Nature |volume=406 |issue= 6796 |pages= 593–9 |year= 2000 |pmid= 10949293 |doi= 10.1038/35020506 }}
*{{cite journal | author=O'Carroll D, Scherthan H, Peters AH, ''et al.'' |title=Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression. |journal=Mol. Cell. Biol. |volume=20 |issue= 24 |pages= 9423-33 |year= 2001 |pmid= 11094092 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Ait-Si-Ali S, Guasconi V, Fritsch L, etal |title=A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells |journal=EMBO J. |volume=23 |issue= 3 |pages= 605–15 |year= 2005 |pmid= 14765126 |doi= 10.1038/sj.emboj.7600074 | pmc=1271807 }}
*{{cite journal | author=Ait-Si-Ali S, Guasconi V, Fritsch L, ''et al.'' |title=A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells. |journal=EMBO J. |volume=23 |issue= 3 |pages= 605-15 |year= 2005 |pmid= 14765126 |doi= 10.1038/sj.emboj.7600074 }}
*{{cite journal   |vauthors=Frontelo P, Leader JE, Yoo N, etal |title=Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression |journal=Oncogene |volume=23 |issue= 30 |pages= 5242–51 |year= 2004 |pmid= 15107829 |doi= 10.1038/sj.onc.1207660 }}
*{{cite journal | author=Frontelo P, Leader JE, Yoo N, ''et al.'' |title=Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression. |journal=Oncogene |volume=23 |issue= 30 |pages= 5242-51 |year= 2004 |pmid= 15107829 |doi= 10.1038/sj.onc.1207660 }}
*{{cite journal   |vauthors=Deloukas P, Earthrowl ME, Grafham DV, etal |title=The DNA sequence and comparative analysis of human chromosome 10 |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 }}
*{{cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375-81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Yoon KA, Hwangbo B, Kim IJ, etal |title=Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer |journal=Carcinogenesis |volume=27 |issue= 11 |pages= 2217–22 |year= 2006 |pmid= 16774942 |doi= 10.1093/carcin/bgl084 }}
*{{cite journal | author=Yoon KA, Hwangbo B, Kim IJ, ''et al.'' |title=Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer. |journal=Carcinogenesis |volume=27 |issue= 11 |pages= 2217-22 |year= 2006 |pmid= 16774942 |doi= 10.1093/carcin/bgl084 }}
}}
}}
{{refend}}
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Latest revision as of 07:19, 11 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Histone-lysine N-methyltransferase SUV39H2 is an enzyme that in humans is encoded by the SUV39H2 gene.[1][2]


References

  1. ↑ O'Carroll D, Scherthan H, Peters AH, Opravil S, Haynes AR, Laible G, Rea S, Schmid M, Lebersorger A, Jerratsch M, Sattler L, Mattei MG, Denny P, Brown SD, Schweizer D, Jenuwein T (Dec 2000). "Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression". Mol Cell Biol. 20 (24): 9423–33. doi:10.1128/MCB.20.24.9423-9433.2000. PMC 102198. PMID 11094092.
  2. ↑ "Entrez Gene: SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)".

Further reading



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