WAPAL: Difference between revisions

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{{Infobox_gene}}
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'''Wings apart-like protein homolog''' is a [[protein]] that in humans is encoded by the ''WAPAL'' [[gene]].<ref name="pmid9039502">{{cite journal | vauthors = Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N | title = Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain | journal = DNA Res | volume = 3 | issue = 5 | pages = 321–9, 341–54 |date=May 1997 | pmid = 9039502 | pmc =  | doi =10.1093/dnares/3.5.321 }}</ref><ref name="pmid17112726">{{cite journal | vauthors = Gandhi R, Gillespie PJ, Hirano T | title = Human Wapl Is a Cohesin-binding Protein that Promotes Sister Chromatid Resolution in Mitotic Prophase | journal = Curr Biol | volume = 16 | issue = 24 | pages = 2406–17 |date=Dec 2006 | pmid = 17112726 | pmc = 1850625 | doi = 10.1016/j.cub.2006.10.061 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: WAPAL wings apart-like homolog (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23063| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Wings apart-like homolog (Drosophila)
| HGNCid = 23293
| Symbol = WAPAL
| AltSymbols =; FOE; KIAA0261; WAPL
| OMIM = 610754
| ECnumber =
| Homologene = 41002
| MGIid = 2675859
  | GeneAtlas_image1 = PBB_GE_WAPAL_212264_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_WAPAL_212267_at_tn.png
  | Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}  
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process =  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 23063
    | Hs_Ensembl = ENSG00000062650
    | Hs_RefseqProtein = NP_055860
    | Hs_RefseqmRNA = NM_015045
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 10
    | Hs_GenLoc_start = 88184993
    | Hs_GenLoc_end = 88271552
    | Hs_Uniprot = Q7Z5K2
    | Mm_EntrezGene = 218914
    | Mm_Ensembl = ENSMUSG00000041408
    | Mm_RefseqmRNA = NM_001004436
    | Mm_RefseqProtein = NP_001004436
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 14
    | Mm_GenLoc_start = 33503020
    | Mm_GenLoc_end = 33575309
    | Mm_Uniprot = Q65Z40
  }}
}}
'''Wings apart-like homolog (Drosophila)''', also known as '''WAPAL''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: WAPAL wings apart-like homolog (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23063| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Nagase T, Seki N, Ishikawa K, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. |journal=DNA Res. |volume=3 |issue= 5 |pages= 321-9, 341-54 |year= 1997 |pmid= 9039502 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Oikawa K, Ohbayashi T, Kiyono T, etal |title=Expression of a novel human gene, human wings apart-like (hWAPL), is associated with cervical carcinogenesis and tumor progression |journal=Cancer Res. |volume=64 |issue= 10 |pages= 3545–9 |year= 2004 |pmid= 15150110 |doi= 10.1158/0008-5472.CAN-03-3822 }}
*{{cite journal | author=Oikawa K, Ohbayashi T, Kiyono T, ''et al.'' |title=Expression of a novel human gene, human wings apart-like (hWAPL), is associated with cervical carcinogenesis and tumor progression. |journal=Cancer Res. |volume=64 |issue= 10 |pages= 3545-9 |year= 2004 |pmid= 15150110 |doi= 10.1158/0008-5472.CAN-03-3822 }}
*{{cite journal   |vauthors=Deloukas P, Earthrowl ME, Grafham DV, etal |title=The DNA sequence and comparative analysis of human chromosome 10 |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 }}
*{{cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375-81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 }}
*{{cite journal  | vauthors=Lehner B, Sanderson CM |title=A Protein Interaction Framework for Human mRNA Degradation |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 | pmc=442147 }}
*{{cite journal  | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315-23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 }}
*{{cite journal   |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 }}
*{{cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
*{{cite journal   |vauthors=Ballif BA, Villén J, Beausoleil SA, etal |title=Phosphoproteomic analysis of the developing mouse brain |journal=Mol. Cell. Proteomics |volume=3 |issue= 11 |pages= 1093–101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 }}
*{{cite journal | author=Ballif BA, Villén J, Beausoleil SA, ''et al.'' |title=Phosphoproteomic analysis of the developing mouse brain. |journal=Mol. Cell Proteomics |volume=3 |issue= 11 |pages= 1093-101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 }}
*{{cite journal  | vauthors=Kwiatkowski BA, Ragoczy T, Ehly J, Schubach WH |title=Identification and cloning of a novel chromatin-associated protein partner of Epstein-Barr nuclear protein 2 |journal=Exp. Cell Res. |volume=300 |issue= 1 |pages= 223–33 |year= 2004 |pmid= 15383329 |doi= 10.1016/j.yexcr.2004.06.028 }}
*{{cite journal  | author=Kwiatkowski BA, Ragoczy T, Ehly J, Schubach WH |title=Identification and cloning of a novel chromatin-associated protein partner of Epstein-Barr nuclear protein 2. |journal=Exp. Cell Res. |volume=300 |issue= 1 |pages= 223-33 |year= 2004 |pmid= 15383329 |doi= 10.1016/j.yexcr.2004.06.028 }}
*{{cite journal   |vauthors=Kuroda M, Oikawa K, Ohbayashi T, etal |title=A dioxin sensitive gene, mammalian WAPL, is implicated in spermatogenesis |journal=FEBS Lett. |volume=579 |issue= 1 |pages= 167–72 |year= 2005 |pmid= 15620708 |doi= 10.1016/j.febslet.2004.11.070 }}
*{{cite journal | author=Kuroda M, Oikawa K, Ohbayashi T, ''et al.'' |title=A dioxin sensitive gene, mammalian WAPL, is implicated in spermatogenesis. |journal=FEBS Lett. |volume=579 |issue= 1 |pages= 167-72 |year= 2005 |pmid= 15620708 |doi= 10.1016/j.febslet.2004.11.070 }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal   |vauthors=Kueng S, Hegemann B, Peters BH, etal |title=Wapl controls the dynamic association of cohesin with chromatin |journal=Cell |volume=127 |issue= 5 |pages= 955–67 |year= 2007 |pmid= 17113138 |doi= 10.1016/j.cell.2006.09.040 }}
*{{cite journal | author=Gandhi R, Gillespie PJ, Hirano T |title=Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. |journal=Curr. Biol. |volume=16 |issue= 24 |pages= 2406-17 |year= 2007 |pmid= 17112726 |doi= 10.1016/j.cub.2006.10.061 }}
*{{cite journal   |vauthors=Ohbayashi T, Oikawa K, Yamada K, etal |title=Unscheduled overexpression of human WAPL promotes chromosomal instability |journal=Biochem. Biophys. Res. Commun. |volume=356 |issue= 3 |pages= 699–704 |year= 2007 |pmid= 17382297 |doi= 10.1016/j.bbrc.2007.03.037 }}
*{{cite journal  | author=Kueng S, Hegemann B, Peters BH, ''et al.'' |title=Wapl controls the dynamic association of cohesin with chromatin. |journal=Cell |volume=127 |issue= 5 |pages= 955-67 |year= 2007 |pmid= 17113138 |doi= 10.1016/j.cell.2006.09.040 }}
*{{cite journal | author=Ohbayashi T, Oikawa K, Yamada K, ''et al.'' |title=Unscheduled overexpression of human WAPL promotes chromosomal instability. |journal=Biochem. Biophys. Res. Commun. |volume=356 |issue= 3 |pages= 699-704 |year= 2007 |pmid= 17382297 |doi= 10.1016/j.bbrc.2007.03.037 }}
}}
}}
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{{refend}}


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Revision as of 22:27, 17 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Wings apart-like protein homolog is a protein that in humans is encoded by the WAPAL gene.[1][2][3]


References

  1. Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (May 1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
  2. Gandhi R, Gillespie PJ, Hirano T (Dec 2006). "Human Wapl Is a Cohesin-binding Protein that Promotes Sister Chromatid Resolution in Mitotic Prophase". Curr Biol. 16 (24): 2406–17. doi:10.1016/j.cub.2006.10.061. PMC 1850625. PMID 17112726.
  3. "Entrez Gene: WAPAL wings apart-like homolog (Drosophila)".

Further reading