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| == Overview == | | == Overview == |
| * The page name should be '''"Diagnostic study of choice for [disease name]"''', with only the first letter of the title capitalized. Note that the page is called "Diagnostic study of choice."
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| * '''Goal:'''
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| **To describe the most efficient/sensitive/specific test that is utilized for diagnosis of [disease name].
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| **To describe the gold standard test for the diagnosis of [disease name].
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| **To describe the diagnostic criteria, which may be based on clinical findings, physical exam signs, pathological findings, lab findings, findings on imaging, or even findings that exclude other diseases.
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| * As with all microchapter pages linking to the main page, at the top of the edit box put <nowiki>{{CMG}}</nowiki>, your name template, and the microchapter navigation template you created at the beginning.
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| * Remember to create links within WikiDoc by placing <nowiki>[[square brackets]]</nowiki> around key words which you want to link to other pages. Make sure you makes your links as specific as possible. For example, if a sentence contained the phrase anterior spinal artery syndrome, the link should be to [[anterior spinal artery syndrome]] not [[anterior]] or [[artery]] or [[syndrome]]. For more information on how to create links, click [[here]].
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| * Remember to follow the same format and capitalization of letters as outlined in the template below.
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| * You should include the name of the disease in the first sentence of every subsection.
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| == Diagnostic Study of Choice == | | == Diagnostic Study of Choice == |
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| ===== Template statements =====
| | GSD type 1 is diagnosed by identification of proband by either of the following: |
| | | * Biallelic pathogenic variants in ''G6PC'' (GSDIa) or ''SLC37A4'' (GSDIb) on molecular genetic testing |
| === Gold standard/Study of choice: ===
| | * Deficient hepatic enzyme activity |
| * [Name of the investigation] is the gold standard test for the diagnosis of [disease name].
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| * The following result of [gold standard test] is confirmatory of [disease name]:
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| ** Result 1
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| ** Result 2
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| * The [name of investigation] should be performed when:
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| ** The patient presented with symptoms/signs 1. 2, 3.
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| ** A positive [test] is detected in the patient.
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| * [Name of the investigation] is the gold standard test for the diagnosis of [disease name].
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| * The diagnostic study of choice for [disease name] is [name of investigation].
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| * There is no single diagnostic study of choice for the diagnosis of [disease name].
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| * There is no single diagnostic study of choice for the diagnosis of [disease name], but [disease name] can be diagnosed based on [name of the investigation 1] and [name of the investigation 2].
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| * [Disease name] is mainly diagnosed based on clinical presentation.
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| * Investigations:
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| ** Among patients who present with clinical signs of [disease name], the [investigation name] is the most specific test for the diagnosis.
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| ** Among patients who present with clinical signs of [disease name], the [investigation name] is the most sensitive test for diagnosis.
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| ** Among patients who present with clinical signs of [disease name], the [investigation name] is the most efficient test for diagnosis.
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| ==== The comparison table for diagnostic studies of choice for [disease name] ====
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| {|
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| |- style="background: #4479BA; color: #FFFFFF; text-align: center;"
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| ! style="background: #FFFFFF; color: #FFFFFF; text-align: center;" |
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| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Sensitivity
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| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Specificity
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| |-
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| ! style="background: #696969; color: #FFFFFF; text-align: center;" |Test 1
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| | style="background: #DCDCDC; padding: 5px; text-align: center;" |✔
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| | style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
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| |-
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| ! style="background: #696969; color: #FFFFFF; text-align: center;" |Test 2
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| | style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
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| | style="background: #DCDCDC; padding: 5px; text-align: center;" |✔
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| |}
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| <small> ✔= The best test based on the feature </small>
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| ===== Diagnostic results =====
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| The following result of [investigation name] is confirmatory of [disease name]:
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| * Result 1 | |
| * Result 2
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| ===== Sequence of Diagnostic Studies =====
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| The [name of investigation] should be performed when:
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| * The patient presented with symptoms/signs 1, 2, and 3 as the first step of diagnosis.
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| * A positive [test] is detected in the patient, to confirm the diagnosis.
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| === Diagnostic Criteria ===
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| * Here you should describe the details of the diagnostic criteria.
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| *Always mention the name of the criteria/definition you are about to list (e.g. modified Duke criteria for diagnosis of endocarditis / 3rd universal definition of MI) and cite the primary source of where this criteria/definition is found.
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| *Although not necessary, it is recommended that you include the criteria in a table. Make sure you always cite the source of the content and whether the table has been adapted from another source.
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| *Be very clear as to the number of criteria (or threshold) that needs to be met out of the total number of criteria.
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| *Distinguish criteria based on their nature (e.g. clinical criteria / pathological criteria/ imaging criteria) before discussing them in details.
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| *To view an example (endocarditis diagnostic criteria), click [[Endocarditis diagnosis|here]]
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| *If relevant, add additional information that might help the reader distinguish various criteria or the evolution of criteria (e.g. original criteria vs. modified criteria).
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| *You may also add information about the sensitivity and specificity of the criteria, the pre-test probability, and other figures that may help the reader understand how valuable the criteria are clinically.
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| * [Disease name] is mainly diagnosed based on clinical presentation. There are no established criteria for the diagnosis of [disease name].
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| * There is no single diagnostic study of choice for [disease name], though [disease name] may be diagnosed based on [name of criteria] established by [...].
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| * The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
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| * The diagnosis of [disease name] is based on the [criteria name] criteria, which includes [criterion 1], [criterion 2], and [criterion 3].
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| * [Disease name] may be diagnosed at any time if one or more of the following criteria are met:
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| ** Criteria 1
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| ** Criteria 2
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| ** Criteria 3
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| IF there are clear, established diagnostic criteria:
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| *The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
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| *The diagnosis of [disease name] is based on the [criteria name] criteria, which include [criterion 1], [criterion 2], and [criterion 3].
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| *The diagnosis of [disease name] is based on the [definition name] definition, which includes [criterion 1], [criterion 2], and [criterion 3]. | |
| IF there are no established diagnostic criteria:
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| *There are no established criteria for the diagnosis of [disease name].
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| ==References== | | ==References== |