Hashimoto's thyroiditis diagnostic criteria: Difference between revisions
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{{CMG}}; {{AE}} {{MMF}} | {{CMG}}; {{AE}} {{MMF}} | ||
==Overview== | ==Overview== | ||
There are no established criteria for the diagnosis of Hashimoto's thyroiditis. The diagnosis of Hashimoto's thyroiditis is made on laboratory and pathological findings after the clinical suspicion. It includes the [[Thyroid peroxidase|TPO]] antibodies, [[hypothyroidism]], reduced echogenicity on the [[ultrasound]], the presence of [[Germinal center|germinal centers]] and [[lymphocytic]] infiltration of the thyroid gland. | There are no established criteria for the diagnosis of Hashimoto's thyroiditis. The diagnosis of Hashimoto's thyroiditis is made on laboratory and pathological findings after the clinical suspicion. It includes the presence of [[Thyroid peroxidase|TPO]] antibodies, [[hypothyroidism]], reduced echogenicity on the [[ultrasound]], the presence of [[Germinal center|germinal centers]] and [[lymphocytic]] infiltration of the thyroid gland. | ||
==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
There are no established criteria for the diagnosis of Hashimoto's thyroiditis. The diagnosis of Hashimoto's thyroiditis is made based on [[laboratory]], [[ultrasound]], and [[pathological]] findings after the clinical suspicion:<ref name="pmid25535130">{{cite journal |vauthors=Dong YH, Fu DG |title=Autoimmune thyroid disease: mechanism, genetics and current knowledge |journal=Eur Rev Med Pharmacol Sci |volume=18 |issue=23 |pages=3611–8 |year=2014 |pmid=25535130 |doi= |url=}}</ref><ref name="pmid24434360">{{cite journal |vauthors=Caturegli P, De Remigis A, Rose NR |title=Hashimoto thyroiditis: clinical and diagnostic criteria |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=391–7 |year=2014 |pmid=24434360 |doi=10.1016/j.autrev.2014.01.007 |url=}}</ref><ref>{{cite book |last1= Giannini |first1= AJ |authorlink1= |title= The Biological Foundations of Clinical Psychiatry |url= |year= 1986 |publisher= Medical Examination Publishing Company |location= New Hyde Park, NY |language= |isbn= 0-87488-449-7 |oclc= |doi= |id= |page= |pages= 193–198 |quote= |ref= |bibcode= }}</ref><ref>{{cite journal|last=Simmons|first=PJ|title=Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1beta and interleukin-6|journal=Endocrinology|year=1998|volume=139|issue=7|pages=3158–3186|pmid=9645688|doi=10.1210/en.139.7.3148}}</ref> | |||
*Laboratory findings | |||
**Presence of [[Thyroid peroxidase|TPO antibodies]] | |||
**Low [[T3]] and [[T4]] | |||
**High [[TSH]] | |||
* | *[[Ultrasound]] findings | ||
**Reduced [[echogenicity]] | |||
*Pathological findings | |||
**[[Germinal center|Germinal centers]] | |||
**[[Lymphocytic]] infiltration | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 21:06, 18 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
There are no established criteria for the diagnosis of Hashimoto's thyroiditis. The diagnosis of Hashimoto's thyroiditis is made on laboratory and pathological findings after the clinical suspicion. It includes the presence of TPO antibodies, hypothyroidism, reduced echogenicity on the ultrasound, the presence of germinal centers and lymphocytic infiltration of the thyroid gland.
Diagnostic Criteria
There are no established criteria for the diagnosis of Hashimoto's thyroiditis. The diagnosis of Hashimoto's thyroiditis is made based on laboratory, ultrasound, and pathological findings after the clinical suspicion:[1][2][3][4]
- Laboratory findings
- Presence of TPO antibodies
- Low T3 and T4
- High TSH
- Ultrasound findings
- Reduced echogenicity
- Pathological findings
- Germinal centers
- Lymphocytic infiltration
References
- ↑ Dong YH, Fu DG (2014). "Autoimmune thyroid disease: mechanism, genetics and current knowledge". Eur Rev Med Pharmacol Sci. 18 (23): 3611–8. PMID 25535130.
- ↑ Caturegli P, De Remigis A, Rose NR (2014). "Hashimoto thyroiditis: clinical and diagnostic criteria". Autoimmun Rev. 13 (4–5): 391–7. doi:10.1016/j.autrev.2014.01.007. PMID 24434360.
- ↑ Giannini, AJ (1986). The Biological Foundations of Clinical Psychiatry. New Hyde Park, NY: Medical Examination Publishing Company. pp. 193–198. ISBN 0-87488-449-7.
- ↑ Simmons, PJ (1998). "Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1beta and interleukin-6". Endocrinology. 139 (7): 3158–3186. doi:10.1210/en.139.7.3148. PMID 9645688.