Roseola overview: Difference between revisions
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== Classification == | == Classification == | ||
There is no established classification system for roseola. | |||
== Pathophysiology == | == Pathophysiology == |
Revision as of 19:43, 30 May 2017
Roseola Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Roseola overview On the Web |
American Roentgen Ray Society Images of Roseola overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omodamola Aje B.Sc, M.D. [2]
Overview
Roseola is a disease of infants. It is characterized by an abrupt rise in body temperature to as high as 40°C (104°F) followed by a rapid drop to normal within the next 2–4 days which coincides with the appearance of an erythematous maculopapular skin rash that persists for 1–3 days. It is typically a beningn disease which resolves without sequalae. Roseola disease is caused by Human herpes virus 6 (HHV6). HHV-6 is a member of the Herpesvirales order, Herpesviridae family, Betaherpesvirinae subfamily, and Roseolovirus genus. HHV-6A and HHV-6B are two distinct species of HHV-6.
Historical perspective
Human herpes virus 6 was first identified in 1986. Herpesviruses have a unique four-layered structure: a core containing the large, double-stranded DNA genome is enclosed by an icosapentahedral capsid which is composed of capsomers. The capsid is surrounded by an amorphous protein coat called the tegument. It is encased in a glycoprotein-bearing lipid bilayer envelope.
Classification
There is no established classification system for roseola.