Tropical sprue natural history, complications and prognosis: Difference between revisions

Jump to navigation Jump to search
Line 7: Line 7:
==Natural History, Complications and Prognosis==
==Natural History, Complications and Prognosis==
===Natural History===
===Natural History===
Tropical sprue is a diagnosis of exclusion, patients present with chronic non-bloody diarrhea following an episode of infectious diarrhea. Patients present with diarrhea, severe form of tropical sprue causes vitamin B12 and vitamin A deficiencies resulting in neurological symptoms and visual disturbances. If left untreated it is associated with significant morbidity and mortality, therefore suspicion of tropical sprue must be high if histology of the duodenal biopsy demonstrates villous atrophy and the patient is unresponsive to a gluten free diet.
Tropical sprue is a diagnosis of exclusion, patients present with chronic non-bloody diarrhea following an episode of infectious diarrhea. Patients present with diarrhea and severe form of tropical sprue causes vitamin B12 and vitamin A deficiencies resulting in neurological symptoms and visual disturbances. If left untreated it is associated with significant morbidity and mortality, therefore suspicion of tropical sprue must be high if histology of the duodenal biopsy demonstrates villous atrophy and if the patient is unresponsive to a gluten free diet.


===Complications===
===Complications===

Revision as of 17:01, 12 April 2017

Tropical sprue Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Tropical sprue from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Tropical sprue natural history, complications and prognosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Tropical sprue natural history, complications and prognosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Tropical sprue natural history, complications and prognosis

CDC on Tropical sprue natural history, complications and prognosis

Tropical sprue natural history, complications and prognosis in the news

Blogs on Tropical sprue natural history, complications and prognosis

Directions to Hospitals Treating Tropical sprue

Risk calculators and risk factors for Tropical sprue natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Natural History, Complications and Prognosis

Natural History

Tropical sprue is a diagnosis of exclusion, patients present with chronic non-bloody diarrhea following an episode of infectious diarrhea. Patients present with diarrhea and severe form of tropical sprue causes vitamin B12 and vitamin A deficiencies resulting in neurological symptoms and visual disturbances. If left untreated it is associated with significant morbidity and mortality, therefore suspicion of tropical sprue must be high if histology of the duodenal biopsy demonstrates villous atrophy and if the patient is unresponsive to a gluten free diet.

Complications

The complications of tropical sprue include:

  • Vitamin B12 deficiency causes sub acute combined degeneration of the spinal cord resulting in neurological symptoms.
  • Vitamin A deficiency causes visual disturbances and night blindness
  • Hypokalemia can occur due to chronic diarrhea

Prognosis

All the patients with tropical sprue have excellent prognosis with tetracycline treatment. Treatment is continued for a period of 6 months but the symptoms resolve within 2 to 3 weeks from initiation of therapy.

References


Template:WS Template:WH