Cementoblastoma: Difference between revisions
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===Age=== | ===Age=== | ||
*Cementoblastoma is more commonly observed among patients aged 25 to 30 years old. | *Cementoblastoma is more commonly observed among patients aged 25 to 30 years old. | ||
*Cementoblastoma is more commonly observed among young and middle aged adults. | *Cementoblastoma is more commonly observed among young and middle aged adults. | ||
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==Risk Factors== | ==Risk Factors== | ||
*Common risk factors in the development of cementoblastoma | *Common risk factors in the development of cementoblastoma, include: | ||
:* | |||
:* | |||
== Natural History, Complications and Prognosis== | == Natural History, Complications and Prognosis== | ||
*The majority of patients with cementoblastoma | *The majority of patients with cementoblastoma are initially asymptomatic. | ||
*Early clinical features include tooth pain, swelling, and | *Early clinical features include tooth pain, swelling, and | ||
*If left untreated, | *If left untreated, patients with cementoblastoma may progress to develop | ||
*Common complications of cementoblastoma include | *Common complications of cementoblastoma, include: | ||
*Prognosis is generally | *Prognosis is generally good, and the recurrence rate of patients with cementoblastoma is approximately | ||
== Diagnosis == | == Diagnosis == | ||
=== Symptoms === | === Symptoms === | ||
*Cementoblastoma is usually asymptomatic. | *Cementoblastoma is usually asymptomatic. | ||
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=== Physical Examination === | === Physical Examination === | ||
*Patients with cementoblastoma usually | *Patients with cementoblastoma usually are well-appearing. | ||
* | *Oral examination may be remarkable for: | ||
:*[finding 1] | :*[finding 1] | ||
:*[finding 2] | :*[finding 2] | ||
Line 98: | Line 97: | ||
:*There is usually apparent external resorption of the root where the tumor and the root join. | :*There is usually apparent external resorption of the root where the tumor and the root join. | ||
:*Severe hypercementosis may be present | :*Severe hypercementosis may be present | ||
====Gallery==== | |||
=== | |||
== Treatment == | == Treatment == | ||
=== Medical Therapy === | === Medical Therapy === | ||
*There is no treatment for cementoblastoma; the mainstay of therapy is | *There is no treatment for cementoblastoma; the mainstay of therapy is surgery. | ||
=== Surgery === | === Surgery === | ||
*Surgery is the mainstay of therapy for cementoblastoma. | *Surgery is the mainstay of therapy for cementoblastoma. |
Revision as of 19:22, 25 April 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Synonyms and keywords: Synonym 1; Synonym 2; Synonym 3
Overview
'Cementoblastoma (also known as benign cementoblastoma) is a relatively rare benign neoplasm of the cementum of the teeth. Cementoblastoma is derived from ectomesenchyme of odontogenic origin.[1] Less than 0.69%–8% of all odontogenic tumors.
Historical Perspective
- Cementoblastoma was first discovered by Norberg in 1930.
Classification
- According to the World Health Organization, cementoblastoma is classified as a true cemental neoplasm.
Pathophysiology
- The pathogenesis of cementoblastoma is characterized by [feature1], [feature2], and [feature3].
- Cementoblastoma is commonly located in the mandibular molar area.
- There are no genetic mutations associated with the development of cementoblastoma.
- On gross pathology, characteristic findings of cementoblastoma, include:
- Dense homogenous, irregular, and spherical mass.
- Tooth root
- On microscopic histopathological analysis, characteristic findings of cementoblastoma, include:
- Large globules fused to form a mass
- Composed of proliferative fibrovascular stroma
- Trabeculae lined by plump osteoblasts
Causes
- Common causes of cementoblastoma, include:
Differentiating Cementoblastoma from Other Diseases
- Cementoblastoma must be differentiated from other diseases that cause tooth pain, or swelling, such as:
- Sclerosing osteomyelitis
- Osteoblastoma
- Periapical cemental dysplasia
- Osteitis
- Hypercementosis.
Epidemiology and Demographics
- The prevalence of cementoblastoma is approximately [number or range] per 100,000 individuals worldwide.
- In [year], the incidence of cementoblastoma was estimated to be [number or range] cases per 100,000 individuals in [location].
Age
- Cementoblastoma is more commonly observed among patients aged 25 to 30 years old.
- Cementoblastoma is more commonly observed among young and middle aged adults.
Gender
- Cementoblastoma affects men and women equally.
Race
- There is no racial predilection for cementoblastoma.
Risk Factors
- Common risk factors in the development of cementoblastoma, include:
Natural History, Complications and Prognosis
- The majority of patients with cementoblastoma are initially asymptomatic.
- Early clinical features include tooth pain, swelling, and
- If left untreated, patients with cementoblastoma may progress to develop
- Common complications of cementoblastoma, include:
- Prognosis is generally good, and the recurrence rate of patients with cementoblastoma is approximately
Diagnosis
Symptoms
- Cementoblastoma is usually asymptomatic.
- Symptoms of cementoblastoma may include the following:
- [symptom 1]
- [symptom 2]
- [symptom 3]
- [symptom 4]
- [symptom 5]
- [symptom 6]
Physical Examination
- Patients with cementoblastoma usually are well-appearing.
- Oral examination may be remarkable for:
- [finding 1]
- [finding 2]
- [finding 3]
- [finding 4]
- [finding 5]
- [finding 6]
Laboratory Findings
- There are no specific laboratory findings associated with cementoblastoma.
Imaging Findings
- Conventional radiograph is the imaging modality of choice for cementoblastoma.
- On conventional radiograph, characteristic findings of cementoblastoma, include:
- Well defined, markedly radiopaque mass,
- Radiolucent peripheral "line", which overlies and obliterates the tooth root.
- There is usually apparent external resorption of the root where the tumor and the root join.
- Severe hypercementosis may be present
Gallery
Treatment
Medical Therapy
- There is no treatment for cementoblastoma; the mainstay of therapy is surgery.
Surgery
- Surgery is the mainstay of therapy for cementoblastoma.
- [Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of cementoblastoma.
- [Surgical procedure] can only be performed for patients with [disease stage] cementoblastoma.
Prevention
- There are no primary preventive measures available for cementoblastoma.
References
- ↑ Leena S Sankari and K Ramakrishnan, Benign cementoblastoma, Journal of Oral and Maxillofacial Pathology, 2011 Sep-Dec; 15(3): 358–360 at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227271/