Primary cutaneous follicle centre lymphoma natural history, complications and prognosis: Difference between revisions
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* While the annual risk of transformation of systemic follicular lymphoma (FL) is 3%. | * While the annual risk of transformation of systemic follicular lymphoma (FL) is 3%. | ||
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| [[File:Primary cutaneous follicle centre lymphoma image 3.jpg|250px|thumb|upright|Multiple erythematous to purple, sharply demarcated pruritic nodules in the back that enlarged and coalesced | | [[File:Primary cutaneous follicle centre lymphoma image 3.jpg|250px|thumb|upright|Multiple erythematous to purple, sharply demarcated pruritic nodules in the back that enlarged and coalesced originating a tumor measuring 11 × 7cm in diameter with some satellite lesions.<ref name=hindawi> Transformation of a Cutaneous Follicle Center Lymphoma to a Diffuse Large B-Cell Lymphoma—An Unusual Presentation. Hindawi. http://www.hindawi.com/journals/crim/2010/296523/. Accessed on March 02, 2016</ref>]] | ||
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==Prognosis== | ==Prognosis== |
Revision as of 15:05, 2 March 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Prognosis is generally excellent, and the 5-year survival rate of patients with primary cutaneous follicle centre lymphoma is approximately 97%.
Natural History
- Primary cutaneous follicle centre lymphoma shows a predilection for the scalp, forehead, and trunk and dissemination to extracutaneous sites rarely occurs.[1]]]
- Transformation of systemic follicular lymphoma (FL) into aggressive non-Hodgkin's lymphoma is associated with poor prognosis and has been reported with a wide range of frequency (range between 10%–70%).
- While the annual risk of transformation of systemic follicular lymphoma (FL) is 3%.
Prognosis
- Prognosis is generally excellent, and the 5-year survival rate of patients with primary cutaneous follicle centre lymphoma is approximately 97%.
- The International Extranodal Lymphoma Study Group identified three prognostic factors, that are used to assess a cutaneous lymphoma international prognostic index (CLIPI), which is prognostic of disease-free status.[2]
- Elevated LDH
- More than two skin lesions
- Nodular lesions
References
- ↑ 1.0 1.1 Transformation of a Cutaneous Follicle Center Lymphoma to a Diffuse Large B-Cell Lymphoma—An Unusual Presentation. Hindawi. http://www.hindawi.com/journals/crim/2010/296523/. Accessed on March 02, 2016
- ↑ Wilcox RA (2015). "Cutaneous B-cell lymphomas: 2015 update on diagnosis, risk-stratification, and management". Am. J. Hematol. 90 (1): 73–6. doi:10.1002/ajh.23863. PMID 25535037.