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==Overview==
Parotitis was first discovered by Hippocrates in the 5th century B.C.E. Claude D. Johnson M.D. and Ernest W. Goodpasture M.D. discovered the [[mumps]] [[virus]], the most common cause of parotitis. The [[mumps]] [[virus]] was first isolated in 1945 by K. Habel and John Enders, leading to the first clinical trials to develop [[vaccinations]]. The [[mumps]] [[vaccine]] was developed by Maurice Hilleman and colleagues in December 1967, immunizing against the most common parotitis cause.


==Overview==
==Discovery==
The first report of acute bacterial sialadenitis dates back to 1828 described in a 71-year-old man whose [[infection]] progressed to [[gangrene]]. President Garfield died from acute parotitis complicating abdominal surgery.
*Parotitis was first described by Hippocrates in the 5th century B.C.E.<ref name="urlwww.cdc.gov">{{cite web |url=http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/mumps.pdf |title=www.cdc.gov |format= |work= |accessdate=}}</ref>
**The discovery was made by observations of [[swelling]] of the [[parotid]] [[glands]] and the [[testicles]].<ref name="pmid18923686">{{cite journal |vauthors=Conly J, Johnston B |title=Is mumps making a comeback? |journal=Can J Infect Dis Med Microbiol |volume=18 |issue=1 |pages=7–9 |year=2007 |pmid=18923686 |pmc=2542890 |doi= |url=}}</ref>
*In 1934, Claude D. Johnson M.D. and Ernest W. Goodpasture M.D. discovered the [[mumps]] [[virus]], the most common cause of parotitis.<ref name="urlwww.cdc.gov">{{cite web |url=http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/mumps.pdf |title=www.cdc.gov |format= |work= |accessdate=}}</ref>
**They determined that the [[mumps]] virus was transferred by [[saliva]] transmission.<ref name="pmid19870227">{{cite journal |vauthors=Johnson CD, Goodpasture EW |title=AN INVESTIGATION OF THE ETIOLOGY OF MUMPS |journal=J. Exp. Med. |volume=59 |issue=1 |pages=1–19 |year=1934 |pmid=19870227 |pmc=2132344 |doi= |url=}}</ref>


==Landmark Events in the Development of Treatment Strategies==
*The [[mumps]] [[virus]] was first isolated in 1945 by K. Habel and John Enders.<ref name="pmid26636066">{{cite journal |vauthors=Hajj Hussein I, Chams N, Chams S, El Sayegh S, Badran R, Raad M, Gerges-Geagea A, Leone A, Jurjus A |title=Vaccines Through Centuries: Major Cornerstones of Global Health |journal=Front Public Health |volume=3 |issue= |pages=269 |year=2015 |pmid=26636066 |pmc=4659912 |doi=10.3389/fpubh.2015.00269 |url=}}</ref>
**This led to the first clinical trials to develop [[vaccinations]].
*The [[mumps]] [[vaccine]] was developed by Maurice Hilleman and colleagues in December 1967, immunizing against the most common parotitis cause.
==References==
==References==
{{reflist|2}}
{{reflist|2}}


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Revision as of 16:47, 1 March 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Parotitis was first discovered by Hippocrates in the 5th century B.C.E. Claude D. Johnson M.D. and Ernest W. Goodpasture M.D. discovered the mumps virus, the most common cause of parotitis. The mumps virus was first isolated in 1945 by K. Habel and John Enders, leading to the first clinical trials to develop vaccinations. The mumps vaccine was developed by Maurice Hilleman and colleagues in December 1967, immunizing against the most common parotitis cause.

Discovery

  • Parotitis was first described by Hippocrates in the 5th century B.C.E.[1]
  • In 1934, Claude D. Johnson M.D. and Ernest W. Goodpasture M.D. discovered the mumps virus, the most common cause of parotitis.[1]
    • They determined that the mumps virus was transferred by saliva transmission.[3]

Landmark Events in the Development of Treatment Strategies

  • The mumps virus was first isolated in 1945 by K. Habel and John Enders.[4]
    • This led to the first clinical trials to develop vaccinations.
  • The mumps vaccine was developed by Maurice Hilleman and colleagues in December 1967, immunizing against the most common parotitis cause.

References

  1. 1.0 1.1 "www.cdc.gov" (PDF).
  2. Conly J, Johnston B (2007). "Is mumps making a comeback?". Can J Infect Dis Med Microbiol. 18 (1): 7–9. PMC 2542890. PMID 18923686.
  3. Johnson CD, Goodpasture EW (1934). "AN INVESTIGATION OF THE ETIOLOGY OF MUMPS". J. Exp. Med. 59 (1): 1–19. PMC 2132344. PMID 19870227.
  4. Hajj Hussein I, Chams N, Chams S, El Sayegh S, Badran R, Raad M, Gerges-Geagea A, Leone A, Jurjus A (2015). "Vaccines Through Centuries: Major Cornerstones of Global Health". Front Public Health. 3: 269. doi:10.3389/fpubh.2015.00269. PMC 4659912. PMID 26636066.

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