Primary central nervous system lymphoma laboratory tests: Difference between revisions
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===CSF Analysis=== | ===CSF Analysis=== | ||
*CSF examination demonstrates elevated protein and decreased glucose.<ref name=pathologyofprimarycentralknervouissystemlymphomaradiopeadk1>Pathology of primary central system lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | *CSF examination demonstrates [[protein|elevated protein]] and [[glucose|decreased glucose]].<ref name=pathologyofprimarycentralknervouissystemlymphomaradiopeadk1>Pathology of primary central system lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | ||
*Positive cytology is uncommon (~25%). | *Positive cytology is uncommon (~25%). | ||
*Positive [[EBV|EBV DNA]] in [[PCR|CSF-PCR]] is helpful for diagnosis of primary central nervous system lymphoma, particularly in HIV/AIDS patients.<ref name=pathologyofprimarycentralknervouissystemlymphomaradiopeadk1>Pathology of primary central system lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | *Positive [[EBV|EBV DNA]] in [[PCR|CSF-PCR]] is helpful for diagnosis of primary central nervous system lymphoma, particularly in HIV/AIDS patients.<ref name=pathologyofprimarycentralknervouissystemlymphomaradiopeadk1>Pathology of primary central system lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> |
Revision as of 19:18, 18 February 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Laboratory Findings
- CD4+ count - Mean CD4+ count at time of diagnosis is ~50/uL.
CSF Analysis
- CSF examination demonstrates elevated protein and decreased glucose.[1]
- Positive cytology is uncommon (~25%).
- Positive EBV DNA in CSF-PCR is helpful for diagnosis of primary central nervous system lymphoma, particularly in HIV/AIDS patients.[1]
References
- ↑ 1.0 1.1 Pathology of primary central system lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016