Enteropathy-associated T-cell lymphoma natural history, complications and prognosis: Difference between revisions
No edit summary |
(/* Natural HistoryEnteropathy-associated T-cell lymphoma . Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/enteropathy-associated-t-cell-lymphoma/?region=on Accessed...) |
||
Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
Enteropathy-associated T-cell lymphoma is usually a fast-growing (aggressive) lymphoma. Common complications of enteropathy-associated T-cell lymphoma include [[ulcer]], [[obstruction]], and [[perforation]] of small intestine.<ref name= canadiancancer>Enteropathy-associated T-cell lymphoma . Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/enteropathy-associated-t-cell-lymphoma/?region=on Accessed on January 27, 2016 </ref>Prognosis is generally poor. | Enteropathy-associated T-cell lymphoma is usually a fast-growing (aggressive) lymphoma. Common complications of enteropathy-associated T-cell lymphoma include [[ulcer]], [[obstruction]], and [[perforation]] of small intestine.<ref name= canadiancancer>Enteropathy-associated T-cell lymphoma . Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/enteropathy-associated-t-cell-lymphoma/?region=on Accessed on January 27, 2016 </ref>Prognosis is generally poor. | ||
==Natural History<ref name= canadiancancer>Enteropathy-associated T-cell lymphoma . Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/enteropathy-associated-t-cell-lymphoma/?region=on Accessed on January 27, 2016 </ref> | ==Natural History== | ||
* Enteropathy-associated T-cell lymphoma is usually a fast-growing (aggressive) lymphoma.<ref name= canadiancancer>Enteropathy-associated T-cell lymphoma . Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/enteropathy-associated-t-cell-lymphoma/?region=on Accessed on January 27, 2016 </ref> | |||
* Enteropathy-associated T-cell lymphoma is associated with celiac disease (sprue). | * Enteropathy-associated T-cell lymphoma is associated with celiac disease (sprue). | ||
* Most adults are diagnosed with [[celiac disease]] at the same time as their lymphoma or shortly before their lymphoma is diagnosed. | * Most adults are diagnosed with [[celiac disease]] at the same time as their lymphoma or shortly before their lymphoma is diagnosed. | ||
* Enteropathy-associated T-cell lymphoma may spread to the liver, spleen, lymph nodes, gallbladder, stomach, colon or skin. | * Enteropathy-associated T-cell lymphoma may spread to the liver, spleen, lymph nodes, gallbladder, stomach, colon or skin. | ||
==Complications== | ==Complications== | ||
* Common complications of enteropathy-associated T-cell lymphoma include:<ref name= canadiancancer>Enteropathy-associated T-cell lymphoma . Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/enteropathy-associated-t-cell-lymphoma/?region=on Accessed on January 27, 2016 </ref> | * Common complications of enteropathy-associated T-cell lymphoma include:<ref name= canadiancancer>Enteropathy-associated T-cell lymphoma . Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/enteropathy-associated-t-cell-lymphoma/?region=on Accessed on January 27, 2016 </ref> |
Revision as of 19:37, 16 February 2016
Enteropathy-associated T-cell lymphoma Microchapters |
Differentiating Enteropathy-associated T-cell lymphoma from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Enteropathy-associated T-cell lymphoma natural history, complications and prognosis On the Web |
American Roentgen Ray Society Images of Enteropathy-associated T-cell lymphoma natural history, complications and prognosis |
FDA on Enteropathy-associated T-cell lymphoma natural history, complications and prognosis |
CDC on Enteropathy-associated T-cell lymphoma natural history, complications and prognosis |
Enteropathy-associated T-cell lymphoma natural history, complications and prognosis in the news |
Blogs on Enteropathy-associated T-cell lymphoma natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Enteropathy-associated T-cell lymphoma is usually a fast-growing (aggressive) lymphoma. Common complications of enteropathy-associated T-cell lymphoma include ulcer, obstruction, and perforation of small intestine.[1]Prognosis is generally poor.
Natural History
- Enteropathy-associated T-cell lymphoma is usually a fast-growing (aggressive) lymphoma.[1]
- Enteropathy-associated T-cell lymphoma is associated with celiac disease (sprue).
- Most adults are diagnosed with celiac disease at the same time as their lymphoma or shortly before their lymphoma is diagnosed.
- Enteropathy-associated T-cell lymphoma may spread to the liver, spleen, lymph nodes, gallbladder, stomach, colon or skin.
Complications
- Common complications of enteropathy-associated T-cell lymphoma include:[1]
- Ulcer in small intestine
- Obstruction of small intestine
- Perforation of small intestine
Prognosis
- The prognosis for people with enteropathy-associated T-cell lymphoma is often not very good.[1]
- Recurrences most frequent in the small intestine.[2]
- According to the Peripheral T-Cell Lymphoma Project, median overall survival is ten months, while median failure-free survival is only six months.
- The peripheral index for T-cell lymphoma is useful in defining prognosis for enteropathy-associated T-cell lymphoma.
- The most influential prognostic factor is bulky nature of disease, defined by a tumor mass greater than 5 cm. [3]
- Autologous stem cell transplantation is feasible for selected patients with enteropathy-associated T-cell lymphoma and can yield durable disease control in a significant proportion of these patients.
- One study found a trend for better survival in patients transplanted in first complete or partial remission at four years (66% vs. 36%; P = .062).[4]
References
- ↑ 1.0 1.1 1.2 1.3 Enteropathy-associated T-cell lymphoma . Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/enteropathy-associated-t-cell-lymphoma/?region=on Accessed on January 27, 2016
- ↑ Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 27, 2016
- ↑ Delabie J, et al. (July 2011). "Enteropathy-associated T-cell lymphoma: clinical and histological findings from the International Peripheral T-Cell Lymphoma Project". Blood. 118 (148): 148. doi:10.1182/blood-2011-02-335216.
- ↑ Jantunen, E; Boumendil, A; Finel, H; Luan, J. J.; Johnson, P; Rambaldi, A; Haynes, A; Duchosal, M. A.; Bethge, W; Biron, P; Carlson, K; Craddock, C; Rudin, C; Finke, J; Salles, G; Kroschinsky, F; Sureda, A; Dreger, P; Lymphoma Working Party of the EBMT (2013). "Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: A retrospective study by the EBMT". Blood. 121 (13): 2529–32. doi:10.1182/blood-2012-11-466839. PMID 23361910.