Enteropathy-associated T-cell lymphoma natural history, complications and prognosis: Difference between revisions

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==Prognosis==
==Prognosis==
Recurrences most frequent in the small intestine<ref name=cancer.gov> Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 27, 2016</ref>
* Recurrences most frequent in the small intestine<ref name=cancer.gov> Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 27, 2016</ref>
* According to the Peripheral T-Cell Lymphoma Project, median overall survival is ten months, while median failure-free survival is only six months
* The peripheral index for T-cell lymphoma is useful in defining prognosis for enteropathy-associated T-cell lymphoma
* Among the most influential prognostic factors is bulky disease, defined by a tumor mass greater than 5 cm<ref name="pmid21566094"/>.
* [[Autologous stem cell transplantation]] is feasible for selected patients with enteropathy-associated T-cell lymphoma and can yield durable disease control in a significant proportion of these patients
* One study found a trend for better survival in patients transplanted in first complete or partial remission at four years (66% vs. 36%; P = .062)<ref name="pmid23361910"/>
 
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 16:37, 27 January 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

Prognosis

  • Recurrences most frequent in the small intestine[1]
  • According to the Peripheral T-Cell Lymphoma Project, median overall survival is ten months, while median failure-free survival is only six months
  • The peripheral index for T-cell lymphoma is useful in defining prognosis for enteropathy-associated T-cell lymphoma
  • Among the most influential prognostic factors is bulky disease, defined by a tumor mass greater than 5 cm[2].
  • Autologous stem cell transplantation is feasible for selected patients with enteropathy-associated T-cell lymphoma and can yield durable disease control in a significant proportion of these patients
  • One study found a trend for better survival in patients transplanted in first complete or partial remission at four years (66% vs. 36%; P = .062)[3]

References

  1. Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 27, 2016


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