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==Historical Perspective==
==Historical Perspective==
[[Trichinella spiralis]] was first discovered by [[James Paget]], a English  first-year medical student, in 1835.<ref>Trichinosis. Wikipedia.https://en.wikipedia.org/wiki/Trichinosis. Accessed on January 22, 2016</ref> In 1846, Joseph Leidy, an American paleontologist, was the first to discover the association between undercooked meat and development of trichinosis.<ref>Joseph Leidy. Wikipedia.https://en.wikipedia.org/wiki/Joseph_Leidy. Accessed on January 22, 2016</ref> There have been several [[outbreaks]] of trichinosis, most of them for consuming infected pork, wild boar and bear. Although now uncommon as a result of [[public health]] control measures.<ref>Marva E, Markovics A, Gdalevich M, Asor N, Sadik C, and Leventhal A. Trichinellosis Outbreak. ''Emerg Infect Dis.'' 2005;11(12):1979-1981</ref><ref>Wilson N, Hall R, Montgomery S, Jones F. Trichinellosis Surveillance — United States, 2008–2012. ''MMWR'' 2005;11(12):1979-1981</ref>
[[Trichinella spiralis]] was first discovered by [[James Paget]], a English  first-year medical student, in 1835.<ref>Trichinosis. Wikipedia.https://en.wikipedia.org/wiki/Trichinosis. Accessed on January 22, 2016</ref> In 1846, Joseph Leidy, an American paleontologist, was the first to discover the association between undercooked meat and development of trichinosis.<ref>Joseph Leidy. Wikipedia.https://en.wikipedia.org/wiki/Joseph_Leidy. Accessed on January 22, 2016</ref> There have been several [[outbreaks]] of trichinosis, most of them for consuming infected pork, wild boar and bear. Although now uncommon as a result of [[public health]] control measures.<ref>Marva E, Markovics A, Gdalevich M, Asor N, Sadik C, and Leventhal A. Trichinellosis Outbreak. ''Emerg Infect Dis.'' 2005;11(12):1979-1981</ref><ref>Wilson N, Hall R, Montgomery S, Jones F. Trichinellosis Surveillance — United States, 2008–2012. ''MMWR'' 2005;11(12):1979-1981</ref>
==Classification==
Based on the severity of [[signs]] and larval density, trichinosis may be classified into [[asymptomatic]], abortive, mild, pronounced, and severe. <ref name="pmid19136437">{{cite journal| author=Gottstein B, Pozio E, Nöckler K| title=Epidemiology, diagnosis, treatment, and control of trichinellosis. | journal=Clin Microbiol Rev | year= 2009 | volume= 22 | issue= 1 | pages= 127-45, Table of Contents | pmid=19136437 | doi=10.1128/CMR.00026-08 | pmc=PMC2620635 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19136437  }} </ref>


==Pathophysiology==
==Pathophysiology==

Revision as of 19:24, 25 January 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Danitza Lukac

Overview

Trichinosis, also called trichinellosis, or trichiniasis, is a parasitic disease caused by eating raw or undercooked pork and wild game products infected with the larvae of a species of roundworm Trichinella spiralis, commonly called the trichina worm. The few cases in the United States are mostly the result of eating undercooked game or home reared pigs. It is most common in the developing world and where pigs are commonly fed raw garbage.

Historical Perspective

Trichinella spiralis was first discovered by James Paget, a English first-year medical student, in 1835.[1] In 1846, Joseph Leidy, an American paleontologist, was the first to discover the association between undercooked meat and development of trichinosis.[2] There have been several outbreaks of trichinosis, most of them for consuming infected pork, wild boar and bear. Although now uncommon as a result of public health control measures.[3][4]

Classification

Based on the severity of signs and larval density, trichinosis may be classified into asymptomatic, abortive, mild, pronounced, and severe. [5]

Pathophysiology

Causes

Common cause of trichinosis include Trichinella spiralis. Less common causes of trichinosis include T. britovi, T. nativa, T. pseudospiralis, T. papuae, T. nelsoni, T. murrelli, and T. zimbabwensis.[6]

Differential Diagnosis

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

References

  1. Trichinosis. Wikipedia.https://en.wikipedia.org/wiki/Trichinosis. Accessed on January 22, 2016
  2. Joseph Leidy. Wikipedia.https://en.wikipedia.org/wiki/Joseph_Leidy. Accessed on January 22, 2016
  3. Marva E, Markovics A, Gdalevich M, Asor N, Sadik C, and Leventhal A. Trichinellosis Outbreak. Emerg Infect Dis. 2005;11(12):1979-1981
  4. Wilson N, Hall R, Montgomery S, Jones F. Trichinellosis Surveillance — United States, 2008–2012. MMWR 2005;11(12):1979-1981
  5. Gottstein B, Pozio E, Nöckler K (2009). "Epidemiology, diagnosis, treatment, and control of trichinellosis". Clin Microbiol Rev. 22 (1): 127–45, Table of Contents. doi:10.1128/CMR.00026-08. PMC 2620635. PMID 19136437.
  6. Trichinosis. Wikipedia.https://en.wikipedia.org/wiki/Trichinosis. Accessed on January 22, 2016

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