Mycosis fungoides pathophysiology: Difference between revisions
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==Overview== | ==Overview== | ||
==Pathophysiology== | ==Pathophysiology== | ||
* Cutaneous T cell lymphoma is an unusual expression of [[T-cells]], a part of the immune system | |||
"Sézary's cells" are [[T-cells]] that have pathological quantities of [[mucopolysaccharide]]s | * These T-cells are skin-associated, meaning that they biochemically and biologically are most related to the skin, in a dynamic manner | ||
* Sezary syndrome and Mycosis Fungoides are T-cell lymphomas whose primary manifestation is in the skin | |||
* Mycosis Fungoides is the most common type of '[[Cutaneous T cell lymphoma]]' (CTCL) | |||
* Mycosis fungoides is initially an indolent lymphoma but in its later stages can cause peripheral lymphadenopathy and can finally progress to widespread extracutaneous visceral / internal organ involvement | |||
* "Sézary's cells" are [[T-cells]] that have pathological quantities of [[mucopolysaccharide]]s | |||
* Sézary's disease is sometimes considered a late stage of [[mycosis fungoides]] | |||
==Microscopic Pathology== | ==Microscopic Pathology== | ||
<gallery widths=200px> | <gallery widths=200px> | ||
Revision as of 18:52, 20 January 2016
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Cutaneous T cell lymphoma Microchapters |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Pathophysiology
- Cutaneous T cell lymphoma is an unusual expression of T-cells, a part of the immune system
- These T-cells are skin-associated, meaning that they biochemically and biologically are most related to the skin, in a dynamic manner
- Sezary syndrome and Mycosis Fungoides are T-cell lymphomas whose primary manifestation is in the skin
- Mycosis Fungoides is the most common type of 'Cutaneous T cell lymphoma' (CTCL)
- Mycosis fungoides is initially an indolent lymphoma but in its later stages can cause peripheral lymphadenopathy and can finally progress to widespread extracutaneous visceral / internal organ involvement
- "Sézary's cells" are T-cells that have pathological quantities of mucopolysaccharides
- Sézary's disease is sometimes considered a late stage of mycosis fungoides
Microscopic Pathology
-
Sézary's disease
