Biliary cystadenoma and cystadenocarcinoma history and symptoms: Difference between revisions

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{{Biliary cystadenoma and cystadenocarcinoma}}
{{Biliary cystadenoma and cystadenocarcinoma}}
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{{CMG}}
==Overview==
==Overview==
==History and Symptoms==
==History and Symptoms==


The clinical presentation is variable, depending on the size and location of the cyst. Abdominal pain, obstructive jaundice, palpable mass, increasing abdominal girth, nausea, and vomiting are common signs and symptoms.
*The clinical presentation of biliary cystadenoma is variable, depending on the size and location of the tumor.


Biliary cystadenomas range in size from 3 to 40 cm. Large cystadenomas may demonstrate mass effect on adjacent organs or may be associated with [[hepatomegaly]].
*Typically, the patient is a middle-aged woman presenting with abdominal pain and/or discomfort, with distension and a palpable mass..<ref name="Ahanatha PillaiVelayutham2012">{{cite journal|last1=Ahanatha Pillai|first1=Sastha|last2=Velayutham|first2=Vimalraj|last3=Perumal|first3=Senthilkumar|last4=Ulagendra Perumal|first4=Srinivasan|last5=Lakshmanan|first5=Anand|last6=Ramaswami|first6=Sukumar|last7=Ramasamy|first7=Ravi|last8=Sathyanesan|first8=Jeswanth|last9=Palaniappan|first9=Ravichandran|last10=Rajagopal|first10=Surendran|title=Biliary Cystadenomas: A Case for Complete Resection|journal=HPB Surgery|volume=2012|year=2012|pages=1–6|issn=0894-8569|doi=10.1155/2012/501705}}</ref>
 
*Acute presentation is often pain due to intracystic hemorrhage or rupture of the cyst and fever secondary to infection of the cyst.
*Rare presentations include vomiting, dyspepsia, anorexia, and weight loss.<ref name="Ahanatha PillaiVelayutham2012">{{cite journal|last1=Ahanatha Pillai|first1=Sastha|last2=Velayutham|first2=Vimalraj|last3=Perumal|first3=Senthilkumar|last4=Ulagendra Perumal|first4=Srinivasan|last5=Lakshmanan|first5=Anand|last6=Ramaswami|first6=Sukumar|last7=Ramasamy|first7=Ravi|last8=Sathyanesan|first8=Jeswanth|last9=Palaniappan|first9=Ravichandran|last10=Rajagopal|first10=Surendran|title=Biliary Cystadenomas: A Case for Complete Resection|journal=HPB Surgery|volume=2012|year=2012|pages=1–6|issn=0894-8569|doi=10.1155/2012/501705}}</ref>
*In other cases, non specific signs and symptoms may develop, due to compression of neighboring structures, such as jaundice, signs of cholangitis, cyst infection, hemorrhage. Pain is considered the leading symptom in most series, being present in about 80% of cases.
 
*Jaundice is either due to an extrinsic compression of the bile duct, biliary obstruction by an intraluminal tumoural mass, or accretion of mucus secretion from a communicating biliary cystadenoma.
 
*Ascites is secondary to compression of the inferior vena cava or the hepatic veins. Cystadenomas are known to increase in size during pregnancy and following oral contraceptives suggesting hormonal dependency.
 
* Compression of the vena cava or the portal vein may cause lower limb edema or signs of portal hypertension such as splenomegaly.<ref name="RamacciatoNigri2006">{{cite journal|last1=Ramacciato|first1=Giovanni|last2=Nigri|first2=Giuseppe R|last3=D'Angelo|first3=Francesco|last4=Aurello|first4=Paolo|last5=Bellagamba|first5=Riccardo|last6=Colarossi|first6=Cristina|last7=Pilozzi|first7=Emanuela|last8=Del Gaudio|first8=Massimo|journal=World Journal of Surgical Oncology|volume=4|issue=1|year=2006|pages=76|issn=14777819|doi=10.1186/1477-7819-4-76}}</ref>


The clinical presentation of biliary cystadenoma is variable, depending on the size and location of the tumor. Potential symptoms include:<ref name=radio1>Biliary cystadenoma.Dr Yuranga Weerakkody and Radswiki et al.Radiopaedia.org 2015. http://radiopaedia.org/articles/biliary-cystadenoma</ref>
The clinical presentation of biliary cystadenoma is variable, depending on the size and location of the tumor. Potential symptoms include:<ref name=radio1>Biliary cystadenoma.Dr Yuranga Weerakkody and Radswiki et al.Radiopaedia.org 2015. http://radiopaedia.org/articles/biliary-cystadenoma</ref>
right upper quadrant pain
*Right upper quadrant pain
obstructive jaundice
*Increasing abdominal girth (large tumors)
palpable liver edge or mass
 
increasing abdominal girth (large tumors)
*Abdominal fullness and bloating
nausea and vomiting
*Nausea


Typically, the patient is a middle-aged woman presenting with abdominal pain and/or discomfort, with distension and a palpable mass. Rare presentations include vomiting, dyspepsia, anorexia, and weight loss. Acute presentation is often pain due to intracystic hemorrhage or rupture of the cyst and fever secondary to infection of the cyst. Jaundice is either due to an extrinsic compression of the bile duct, biliary obstruction by an intraluminal tumoural mass, or accretion of mucus secretion from a communicating biliary cystadenoma. Ascites is secondary to compression of the inferior vena cava or the hepatic veins. Cystadenomas are known to increase in size during pregnancy and following oral contraceptives suggesting hormonal dependency. Recurrence of a cyst following partial resection should raise a suspicion of cystadenoma.<ref name="Ahanatha PillaiVelayutham2012">{{cite journal|last1=Ahanatha Pillai|first1=Sastha|last2=Velayutham|first2=Vimalraj|last3=Perumal|first3=Senthilkumar|last4=Ulagendra Perumal|first4=Srinivasan|last5=Lakshmanan|first5=Anand|last6=Ramaswami|first6=Sukumar|last7=Ramasamy|first7=Ravi|last8=Sathyanesan|first8=Jeswanth|last9=Palaniappan|first9=Ravichandran|last10=Rajagopal|first10=Surendran|title=Biliary Cystadenomas: A Case for Complete Resection|journal=HPB Surgery|volume=2012|year=2012|pages=1–6|issn=0894-8569|doi=10.1155/2012/501705}}</ref>
*Vomiting


Biliary cystadenomas often are diagnosed incidentally[12], during imaging studies such as ultrasound or CT scan[13]. In other cases, non specific signs and symptoms may develop, due to compression of neighboring structures, such as jaundice, signs of cholangitis, cyst infection, hemorrhage. Pain is considered the leading symptom in most series, being present in about 80% of cases. Nausea, vomiting, abdominal fullness and bloating may also be present. Compression of the vena cava or the portal vein may cause lower limb edema or signs of portal hypertension such as splenomegaly.<ref name="RamacciatoNigri2006">{{cite journal|last1=Ramacciato|first1=Giovanni|last2=Nigri|first2=Giuseppe R|last3=D'Angelo|first3=Francesco|last4=Aurello|first4=Paolo|last5=Bellagamba|first5=Riccardo|last6=Colarossi|first6=Cristina|last7=Pilozzi|first7=Emanuela|last8=Del Gaudio|first8=Massimo|journal=World Journal of Surgical Oncology|volume=4|issue=1|year=2006|pages=76|issn=14777819|doi=10.1186/1477-7819-4-76}}</ref>
Biliary cystadenomas range in size from 3 to 40 cm. Large cystadenomas may demonstrate mass effect on adjacent organs or may be associated with [[hepatomegaly]].


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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[[Category:Disease]]
[[Category:Disease]]
[[Category:Gastroenterology]]
[[Category:Gastroenterology]]

Revision as of 20:02, 17 November 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

History and Symptoms

  • The clinical presentation of biliary cystadenoma is variable, depending on the size and location of the tumor.
  • Typically, the patient is a middle-aged woman presenting with abdominal pain and/or discomfort, with distension and a palpable mass..[1]
  • Acute presentation is often pain due to intracystic hemorrhage or rupture of the cyst and fever secondary to infection of the cyst.
  • Rare presentations include vomiting, dyspepsia, anorexia, and weight loss.[1]
  • In other cases, non specific signs and symptoms may develop, due to compression of neighboring structures, such as jaundice, signs of cholangitis, cyst infection, hemorrhage. Pain is considered the leading symptom in most series, being present in about 80% of cases.
  • Jaundice is either due to an extrinsic compression of the bile duct, biliary obstruction by an intraluminal tumoural mass, or accretion of mucus secretion from a communicating biliary cystadenoma.
  • Ascites is secondary to compression of the inferior vena cava or the hepatic veins. Cystadenomas are known to increase in size during pregnancy and following oral contraceptives suggesting hormonal dependency.
  • Compression of the vena cava or the portal vein may cause lower limb edema or signs of portal hypertension such as splenomegaly.[2]

The clinical presentation of biliary cystadenoma is variable, depending on the size and location of the tumor. Potential symptoms include:[3]

  • Right upper quadrant pain
  • Increasing abdominal girth (large tumors)
  • Abdominal fullness and bloating
  • Nausea
  • Vomiting

Biliary cystadenomas range in size from 3 to 40 cm. Large cystadenomas may demonstrate mass effect on adjacent organs or may be associated with hepatomegaly.


References

  1. 1.0 1.1 Ahanatha Pillai, Sastha; Velayutham, Vimalraj; Perumal, Senthilkumar; Ulagendra Perumal, Srinivasan; Lakshmanan, Anand; Ramaswami, Sukumar; Ramasamy, Ravi; Sathyanesan, Jeswanth; Palaniappan, Ravichandran; Rajagopal, Surendran (2012). "Biliary Cystadenomas: A Case for Complete Resection". HPB Surgery. 2012: 1–6. doi:10.1155/2012/501705. ISSN 0894-8569.
  2. Ramacciato, Giovanni; Nigri, Giuseppe R; D'Angelo, Francesco; Aurello, Paolo; Bellagamba, Riccardo; Colarossi, Cristina; Pilozzi, Emanuela; Del Gaudio, Massimo (2006). World Journal of Surgical Oncology. 4 (1): 76. doi:10.1186/1477-7819-4-76. ISSN 1477-7819. Missing or empty |title= (help)
  3. Biliary cystadenoma.Dr Yuranga Weerakkody and Radswiki et al.Radiopaedia.org 2015. http://radiopaedia.org/articles/biliary-cystadenoma


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