Mesoblastic nephroma pathophysiology: Difference between revisions

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Revision as of 21:08, 2 November 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]

Characteristic findings of mesoblastic nephroma include:^[1]

Classic mesoblastic nephroma

Spindle cells in fasciclesHumphrey, Peter (2008). The Washington manual of surgical pathology. Philadelphia: Lippincott Williams & Wilkins. ISBN 978-0781765275.
Infiltrative border

Cellular mesoblastic nephroma

Mixed mesoblastic nephroma

t(12:15)(p13;q25) ETV6/NTRK3.

↑ Mesoblastic nephroma.Dr Ayush Goel and Dr Yuranga Weerakkody et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/mesoblastic-nephroma

@@ Line 5: / Line 5: @@
 ==Gross Pathology==
-Characteristic findings of mesoblastic nephroma include:
+Characteristic findings of mesoblastic nephroma include:<ref name=radio> Mesoblastic nephroma.Dr Ayush Goel and Dr Yuranga Weerakkody et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/mesoblastic-nephroma </ref>
-* solid un-encapsulated mass
+* Solid un-encapsulated mass
-* often occurs near the renal hilum
+* Often occurs near the renal hilum
-* tends to invade the surrounding structures and renal parenchyma
+* Tends to invade the surrounding structures and renal parenchyma
-* Haemorrhage and necrosis are infrequent
+* Hemorrhage and necrosis are infrequent
 ==Microscopic Pathology==
-Classic
+Classic mesoblastic nephroma
+* Spindle cells in fascicles{{cite book | last = Humphrey | first = Peter | title = The Washington manual of surgical pathology | publisher = Lippincott Williams & Wilkins | location = Philadelphia | year = 2008 | isbn = 978-0781765275 }}
+* Infiltrative border
-* Spindle cells in fascicles.
+Cellular mesoblastic nephroma
-* Infiltrative border.
+* Plump cells with vesicular nuclei
+* Well-defined border
+* Mitotically active
-Cellular
+Mixed mesoblastic nephroma
+* Both classic pattern and cellular pattern areas are present
-* Plump cells with vesicular nuclei.
-* Well-defined border.
-* Mitotically active.
-Mixed
-* both classic pattern and cellular pattern areas are present.
 ==Genetics==