Zollinger-Ellison syndrome natural history, complications and prognosis: Difference between revisions
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==Overview== | |||
If left untreated, patients with Zollinger-Ellison syndrome may progress to develop [[abdominal pain]], [[diarrhea]], and [[heartburn]]<ref name="pmid11144036">{{cite journal| author=Roy PK, Venzon DJ, Shojamanesh H, Abou-Saif A, Peghini P, Doppman JL et al.| title=Zollinger-Ellison syndrome. Clinical presentation in 261 patients. | journal=Medicine (Baltimore) | year= 2000 | volume= 79 | issue= 6 | pages= 379-411 | pmid=11144036 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11144036 }} </ref>. Common complications of Zollinger-Ellison syndrome include upper gastrointestinal [[bleeding]], [[anemia]], and [gastric ulcer perforation]. Prognosis is generally good, and the 5 and 10-year survival rate of patients with Zollinger-Ellison syndrome is approximately 94% and 75%, respectively.<ref name="pmid7903006">{{cite journal| author=Melvin WS, Johnson JA, Sparks J, Innes JT, Ellison EC| title=Long-term prognosis of Zollinger-Ellison syndrome in multiple endocrine neoplasia. | journal=Surgery | year= 1993 | volume= 114 | issue= 6 | pages= 1183-8 | pmid=7903006 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7903006 }} </ref> | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
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[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Syndromes]] | [[Category:Syndromes]] | ||
Revision as of 13:21, 28 September 2015
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Overview
If left untreated, patients with Zollinger-Ellison syndrome may progress to develop abdominal pain, diarrhea, and heartburn[1]. Common complications of Zollinger-Ellison syndrome include upper gastrointestinal bleeding, anemia, and [gastric ulcer perforation]. Prognosis is generally good, and the 5 and 10-year survival rate of patients with Zollinger-Ellison syndrome is approximately 94% and 75%, respectively.[2]
References
- ↑ Roy PK, Venzon DJ, Shojamanesh H, Abou-Saif A, Peghini P, Doppman JL; et al. (2000). "Zollinger-Ellison syndrome. Clinical presentation in 261 patients". Medicine (Baltimore). 79 (6): 379–411. PMID 11144036.
- ↑ Melvin WS, Johnson JA, Sparks J, Innes JT, Ellison EC (1993). "Long-term prognosis of Zollinger-Ellison syndrome in multiple endocrine neoplasia". Surgery. 114 (6): 1183–8. PMID 7903006.