Multiple endocrine neoplasia type 2 MRI: Difference between revisions
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==Overview== | ==Overview== | ||
==MRI== | ==MRI== | ||
===Parathyroid Carcinoma=== | |||
* MRI is infrequently utilized in initial work up because of lower spatial resolution and artifacts. Adenomas can show variable signal intensity on MRI. Reported signal characteristics include: | |||
:* T1 | |||
::* Typically intermediate to low signal | |||
::* Subacute haemorrhage can cause high signal intensiy 6 | |||
::* Fibrosis or old haemorrhage can cause low signal intensity 6 | |||
:* T2 | |||
::* Typically hyperintense | |||
::* Subacute haemorrhage can cause high signal intensity 6 | |||
::* Fibrosis or old haemorrhage can cause low signal intensity 6 | |||
* Since most lesions demonstrate high T2 signal intensity, the addition of contrast for MR scanning does not significantly increase detection. | |||
===Pheochromocytoma=== | ===Pheochromocytoma=== | ||
* MRI is the most sensitive modality for identification of pheochromocytomas, and is particularly useful in cases of extra-adrenal location. The overall sensitivity is said to be 98%.<ref>{{cite book | last = Blake | first = Michael | title = Adrenal imaging | publisher = Humana Press | location = Totowa, NJ | year = 2009 | isbn = 193411586X }}</ref><ref name=Radiopaedia 2015 Pheochromocytoma>{{cite web | title = Radiopedia 2015 Pheochromocytoma [Dr Matt A. Morgan and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/pheochromocytoma-2 }}</ref> | * MRI is the most sensitive modality for identification of pheochromocytomas, and is particularly useful in cases of extra-adrenal location. The overall sensitivity is said to be 98%.<ref>{{cite book | last = Blake | first = Michael | title = Adrenal imaging | publisher = Humana Press | location = Totowa, NJ | year = 2009 | isbn = 193411586X }}</ref><ref name=Radiopaedia 2015 Pheochromocytoma>{{cite web | title = Radiopedia 2015 Pheochromocytoma [Dr Matt A. Morgan and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/pheochromocytoma-2 }}</ref> | ||
* '''T1''' | * '''T1''' |
Revision as of 18:29, 23 September 2015
Multiple endocrine neoplasia type 2 Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
MRI
Parathyroid Carcinoma
- MRI is infrequently utilized in initial work up because of lower spatial resolution and artifacts. Adenomas can show variable signal intensity on MRI. Reported signal characteristics include:
- T1
- Typically intermediate to low signal
- Subacute haemorrhage can cause high signal intensiy 6
- Fibrosis or old haemorrhage can cause low signal intensity 6
- T2
- Typically hyperintense
- Subacute haemorrhage can cause high signal intensity 6
- Fibrosis or old haemorrhage can cause low signal intensity 6
- Since most lesions demonstrate high T2 signal intensity, the addition of contrast for MR scanning does not significantly increase detection.
Pheochromocytoma
- MRI is the most sensitive modality for identification of pheochromocytomas, and is particularly useful in cases of extra-adrenal location. The overall sensitivity is said to be 98%.[1]
- T1
- Slightly hypointense to the remainder of the adrenal
- If necrotic and/or haemorrhagic then signal will be more heterogeneous
- T2
- Markedly hyperintense (lightbulb sign): this is a helpful feature
- Areas of necrosis/haemorrhage/calcification will alter signal
- T1 C+ (Gd)
- Heterogenous enhancement
- Enhancement is prolonged, persisting for as long as 50 minutes[2]
-
Case courtesy of Dr G Balachandran, [7]
Reference
- ↑ Blake, Michael (2009). Adrenal imaging. Totowa, NJ: Humana Press. ISBN 193411586X.
- ↑ Reiser, Maximilian (2008). Magnetic resonance tomography. Berlin: Springer. ISBN 354029354X.
- ↑ "http://radiopaedia.org/">Radiopaedia.org
- ↑ "http://radiopaedia.org/cases/8550">rID: 8550
- ↑ "http://radiopaedia.org/">Radiopaedia.org
- ↑ "http://radiopaedia.org/cases/9920">rID: 9920
- ↑ "http://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="http://radiopaedia.org/cases/10249">rID: 10249