Dermatofibroma overview: Difference between revisions
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
Deep penetrating dermatofibroma may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumors e.g [[dermatofibrosarcoma protuberans]]<ref>{{cite journal |author=Hanly AJ, Jordà M, Elgart GW, Badiavas E, Nassiri M, Nadji M |title=High proliferative activity excludes dermatofibroma: report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors |journal=Arch. Pathol. Lab. Med. |volume=130 |issue=6 |pages=831–4 |year=2006 |month=June |pmid=16740036 |doi=10.1043/1543-2165(2006)130[831:HPAEDR]2.0.CO;2 |url=}}</ref> | |||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Dermatofibromas are harmless benign skin growths, found especially on the legs, that range in size from about 0.5 to 1 cm. Dermatofibromas are hard solitary slow-growing papules (rounded bumps) that may appear in a variety of colours, usually brownish to tan; they are often elevated or pedunculated.
Historical Perspective
Classification
Dermatofibromas are classed as benign skin lesions, meaning that they are completely harmless, though they may be confused with a variety of subcutaneous tumours. Deep penetrating dermatofibromas may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like dermatofibrosarcoma protuberans.
Pathophysiology
Dermatofibromas are composed of disordered collagen laid down by fibroblasts.
Causes
Differential Diagnosis
Deep penetrating dermatofibroma may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumors e.g dermatofibrosarcoma protuberans[1]
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
History and symptoms
Physical Examination
Biopsy
Treatment
Surgery
- ↑ Hanly AJ, Jordà M, Elgart GW, Badiavas E, Nassiri M, Nadji M (2006). "High proliferative activity excludes dermatofibroma: report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors". Arch. Pathol. Lab. Med. 130 (6): 831–4. doi:10.1043/1543-2165(2006)130[831:HPAEDR]2.0.CO;2. PMID 16740036. Unknown parameter
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