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* Spinal epidural abscess<ref>{{cite book | last = Kasper | first = Dennis | title = Harrison's principles of internal medicine | publisher = McGraw Hill Education | location = New York | year = 2015 | isbn = 978-0071802154 }}</ref> | * Spinal epidural abscess<ref>{{cite book | last = Kasper | first = Dennis | title = Harrison's principles of internal medicine | publisher = McGraw Hill Education | location = New York | year = 2015 | isbn = 978-0071802154 }}</ref> | ||
:* Empiric antimicrobial therapy | :* Empiric antimicrobial therapy | ||
::* Preferred regimen: [[Vancomycin]] 15 mg/kg IV q12h {{and}} [[Ceftriaxone]] 2 g Iv q24h | ::* Preferred regimen: [[Vancomycin]] 15 mg/kg IV q12h for 6 weeks {{and}} [[Ceftriaxone]] 2 g Iv q24h for 6 weeks | ||
::: Note: For critically ill patients, a vancomycin loading dose of 20–25 mg/kg may be considered. | ::: Note (1): Decompressive laminectomy in conjunction with long-term antibiotic therapy tailored to culture results is required. | ||
::: Note (2): For critically ill patients, a vancomycin loading dose of 20–25 mg/kg may be considered. | |||
:* Culture-directed antimicrobial therapy | :* Culture-directed antimicrobial therapy | ||
::* Penicillin-susceptible strain | ::* Penicillin-susceptible strain | ||
:::* Preferred regimen: [[Penicillin G]] 4 MU IV q4h | :::* Preferred regimen: [[Penicillin G]] 4 MU IV q4h for 6 weeks | ||
::* Oxacillin-susceptible strain | ::* Oxacillin-susceptible strain | ||
:::* Preferred regimen: [[Oxacillin]] 2 g IV q4h | :::* Preferred regimen: [[Oxacillin]] 2 g IV q4h for 6 weeks | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 19:35, 1 June 2015
Epidural abscess
- Spinal epidural abscess[1]
- Empiric antimicrobial therapy
- Preferred regimen: Vancomycin 15 mg/kg IV q12h for 6 weeks AND Ceftriaxone 2 g Iv q24h for 6 weeks
- Note (1): Decompressive laminectomy in conjunction with long-term antibiotic therapy tailored to culture results is required.
- Note (2): For critically ill patients, a vancomycin loading dose of 20–25 mg/kg may be considered.
- Culture-directed antimicrobial therapy
- Penicillin-susceptible strain
- Preferred regimen: Penicillin G 4 MU IV q4h for 6 weeks
- Oxacillin-susceptible strain
- Preferred regimen: Oxacillin 2 g IV q4h for 6 weeks
References
- ↑ Kasper, Dennis (2015). Harrison's principles of internal medicine. New York: McGraw Hill Education. ISBN 978-0071802154.