There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
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|offLabelAdultNoGuideSupport======Condition1=====
* Dosing Information
:* Dosage
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There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
<!--Pediatric Indications and Dosage-->
<!--FDA-Labeled Indications and Dosage (Pediatric)-->
|fdaLIADPed======Condition1=====
* Dosing Information
:* Dosage
=====Condition2=====
There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.
<!--Off-Label Use and Dosage (Pediatric)-->
<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport======Condition1=====
* Developed by:
* Class of Recommendation:
* Strength of Evidence:
* Dosing Information
:* Dosage
=====Condition2=====
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport======Condition1=====
* Dosing Information
:* Dosage
=====Condition2=====
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
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|contraindications=* Condition1
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|warnings=* Description
====Precautions====
* Description
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<!--Clinical Trials Experience-->
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
=====Body as a Whole=====
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|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
=====Body as a Whole=====
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=====Metabolic and Nutritional=====
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=====Urogenital=====
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<!--Drug Interactions-->
|drugInteractions=* Drug
:* Description
<!--Use in Specific Populations-->
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of {{PAGENAME}} in women who are pregnant.
|useInLaborDelivery=There is no FDA guidance on use of {{PAGENAME}} during labor and delivery.
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<!--Administration and Monitoring-->
|administration=* Oral
* Intravenous
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|overdose====Acute Overdose===
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====Management====
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<!--Pharmacology-->
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|drugBox=<!--Mechanism of Action-->
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|structure=*
: [[File:{{PAGENAME}}01.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
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|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
<!--Brand Names-->
|brandNames=* ®<ref>{{Cite web | title = | url = }}</ref>
'''Ipecacuanha''' (''Psychotria ipecacuanha'') of family [[Rubiaceae]] is a [[flowering plant]], the root of which is most commonly used to make [[syrup of ipecac]], a powerful [[emetic]]. Its name comes from the [[Tupi language|Tupi]] ''i-pe-kaa-guéne'', translated as 'road-side sick-making plant'. It is native to [[Brazil]]. The plant had been assigned different names by various [[botany|botanists]]; several scientific names including ''Cephaelis acuminata'', ''Cephaelis ipecacuanha'', ''Psychotria ipecacuanha'', and ''Uragoga ipecacuanha'' were used.
<!--Look-Alike Drug Names-->
|lookAlike=* A® — B®<ref name="www.ismp.org">{{Cite web | last = | first = | title = http://www.ismp.org | url = http://www.ismp.org | publisher = | date = }}</ref>
Ipecacuanha was first introduced to [[Europe]] in 1672, by a traveler named Legros. Legros imported some quantity of the root to [[Paris, France|Paris]] from [[South America]]. In 1680, a Parisian merchant named Garnier possessed some 68 kilograms (150 pounds) of the substance and informed a physician named [[Helvetius]] of its power in the treatment of [[dysentery]]. Helvetius was granted sole right to vend the remedy by [[Louis XIV of France|Louis XIV]], but sold the secret to the [[French government]], who made the [[formula]] public in 1688.
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The part of ipecacuanha used in medicine is the root, which is simple or divided into a few branches, flexuous, about as thick as a goose [[quill]], and is composed of rings of various size, somewhat fleshy when fresh, and appearing as if closely strung on a central woody cord. The different kinds known in commerce (gray, red, brown) are all produced by the same plant, the differences arising from the age of the plant, the mode of drying, etc. Various other plants are used as substitutes for it.
Ipecacuanha is useful as an [[emetic]] when it is necessary to unload the stomach in cases where there is great debility or in childhood. As a [[nauseant]], [[expectorant]], and [[diaphoretic]], it is prescribed in [[bronchitis]], etc., and in disorders in which it is desired to increase the actions of the skin. The most useful preparations are the [[syrup of ipecac|wine of ipecacuanha]] and [[Dover's powder]].
==Similar plants==
<!--Label Display Image-->
Ipecacuanha is a slow-growing plant, which reduces its commercial appeal as a crop plant. It is seldom cultivated in [[South America]], but it has been cultivated in [[India]] and elsewhere.
Botanical naming practices vary and change a great deal, thus the following is a generalized listing of plants which have at some point in time been employed as substitutes for ipecacuanha. Some of the names of the species may be obsolete.
*Brazilian or Rio ipecacuanha: ''Cephaelis ipecacuanha''{{Verify source|date=September 2007}}
*Cartagena or Colombia ipecacuanha: ''Cephaelis acuminata''{{Verify source|date=September 2007}}
*Wild ipecacuanha: ''Euphorbia ipecacuanhae'' of [[North America]]
*[[Venezuela|Venezuelan]] plant: ''Sarcostemma glacum'', of the family [[Asclepiadaceae]]
*''Tylophora asthmatica'' was used in [[India]]
*''Gillenia stipulata'' was called American ipecac
*''Richardsonia pilosa, Richardsonia rosea, Psychotria emetica'' and various species of ''Ionidium'' have been employed, too.
==Other==
*Ipecacuanha was the name of the ship that initially rescued the character Edward Prendick in the novel ''[[The Island of Doctor Moreau]]'' written by [[H. G. Wells]]. The ship he had been on, the Lady Vain, collided with rocks, and he was left to float in a dingy until he was rescued eight days later.
*[[Guybrush Threepwood]] used Ipecacuanha syrup (made by combining a flower from the Ipecacuanha with maple syrup) in order to escape from the giant snake that swallowed him in ''[[The Curse of Monkey Island|Monkey Island 3: The Curse of Monkey Island]]'' [[videogame]].
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Black Box Warning
ConditionName:
See full prescribing information for complete Boxed Warning.
ConditionName:
Content
Overview
Ipecacuanha is a {{{drugClass}}} that is FDA approved for the of . There is a Black Box Warning for this drug as shown here. Common adverse reactions include .
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
Condition1
Dosing Information
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Condition2
Dosing Information
Dosage
Condition3
Dosing Information
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Condition4
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Off-Label Use and Dosage (Adult)
Guideline-Supported Use
Condition1
Developed by:
Class of Recommendation:
Strength of Evidence:
Dosing Information
Dosage
Condition2
There is limited information regarding Off-Label Guideline-Supported Use of Ipecacuanha in adult patients.
Non–Guideline-Supported Use
Condition1
Dosing Information
Dosage
Condition2
There is limited information regarding Off-Label Non–Guideline-Supported Use of Ipecacuanha in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
Condition1
Dosing Information
Dosage
Condition2
There is limited information regarding FDA-Labeled Use of Ipecacuanha in pediatric patients.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
Condition1
Developed by:
Class of Recommendation:
Strength of Evidence:
Dosing Information
Dosage
Condition2
There is limited information regarding Off-Label Guideline-Supported Use of Ipecacuanha in pediatric patients.
Non–Guideline-Supported Use
Condition1
Dosing Information
Dosage
Condition2
There is limited information regarding Off-Label Non–Guideline-Supported Use of Ipecacuanha in pediatric patients.
Contraindications
Condition1
Warnings
ConditionName:
See full prescribing information for complete Boxed Warning.
ConditionName:
Content
Description
Precautions
Description
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Clinical Trial Experience of Ipecacuanha in the drug label.
Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous
Postmarketing Experience
There is limited information regarding Postmarketing Experience of Ipecacuanha in the drug label.