Cilostazol detailed information: Difference between revisions
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==Overview== | ==Overview== | ||
'''Cilostazol''' {{IPAc-en|s|ɨ|ˈ|l|ɒ|s|t|ə|z|ɒ|l}} is a quinolinone-derivative [[medication]] used in the alleviation of the [[symptom]] of [[intermittent claudication]] in individuals with [[peripheral vascular disease]]. It is manufactured by [[Otsuka Pharmaceutical Co.]] under the [[trade name]] '''Pletal'''. | |||
Although drugs similar to cilostazol have increased the risk of death in patients with [[congestive heart failure]], studies of significant size have not addressed people without the disease. | |||
Cilostazol is a [[phosphodiesterase inhibitor]] with therapeutic focus on [[Cyclic adenosine monophosphate|cAMP]]. It inhibits platelet aggregation and is a direct arterial vasodilator. Its main effects are dilation of the [[artery|arteries]] supplying [[blood]] to the legs and decreasing [[platelet]] [[coagulation]]. | |||
==Category== | ==Category== | ||
Revision as of 15:57, 28 February 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
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Overview
Cilostazol /s[invalid input: 'ɨ']ˈlɒstəzɒl/ is a quinolinone-derivative medication used in the alleviation of the symptom of intermittent claudication in individuals with peripheral vascular disease. It is manufactured by Otsuka Pharmaceutical Co. under the trade name Pletal.
Although drugs similar to cilostazol have increased the risk of death in patients with congestive heart failure, studies of significant size have not addressed people without the disease.
Cilostazol is a phosphodiesterase inhibitor with therapeutic focus on cAMP. It inhibits platelet aggregation and is a direct arterial vasodilator. Its main effects are dilation of the arteries supplying blood to the legs and decreasing platelet coagulation.
Category
US Brand Names
PLETAL®, Cilostazol®.
FDA Package Insert
| Indications and Usage | Dosage and Administration | Dosage Forms and Strengths | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Use in Specific Populations | Overdosage | Description | Clinical Pharmacology | Nonclinical Toxicology | Clinical Studies | How Supplied/Storage and Handling | Patient Counseling Information | Labels and Packages