Pyelonephritis medical therapy: Difference between revisions
No edit summary |
No edit summary |
||
Line 4: | Line 4: | ||
==Medical Therapy== | ==Medical Therapy== | ||
|- | |- | ||
| valign=top | | | valign=top | |
Revision as of 14:25, 17 January 2014
Pyelonephritis Microchapters |
Diagnosis |
Treatment |
Case Studies |
Pyelonephritis medical therapy On the Web |
American Roentgen Ray Society Images of Pyelonephritis medical therapy |
Risk calculators and risk factors for Pyelonephritis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Medical Therapy
|- | valign=top |
Acute Bacterial Uncomplicated Pyelonephritis |
---|
Preferred Regimen |
▸ Fluoroquinolones Ciprofloxacin 500 mg PO bid ×7 days Levofloxacin 750 mg PO q24 × 5 days Ofloxacin 400 mg Po bid Moxifloxacin 400 mg PO q24h |
Alternative Regimen(14 day regimen) |
▸ TMP-SMX 160/800 mg PO bid OR ▸ Oralβ-lactam Amoxicillin-clavulanate 875/125 mg po q12h or 500/125 mg po tid or 1000 /125 mg po bid Cefdinir 300 mg po q12h or 600 mg po q24 Cefaclor 250-500 mg po q8h Cefpodoxime-proxetil 100-200 mg po q12h Cephalexin250-500 mg po q6h not studied well but effective. |
As practically all cases of pyelonephritis are due to bacterial infections, antibiotics are the mainstay of treatment. Mild cases may be treated with oral therapy, but generally intravenous antibiotics are required for the initial stages of treatment. The type of antibiotic depends on local practice, and may include fluoroquinolones (e.g. ciprofloxacin), beta-lactam antibiotics (e.g. amoxicillin or a cephalosporin), trimethoprim (or co-trimoxazole) or nitrofurantoin. Aminoglycosides are avoided due to their toxicity, but may be added for a short duration.
If the patient is unwell and septic, intravenous fluids may be administered to compensate for the reduced oral intake, insensible losses (due to the raised temperature) and vasodilation and to maximize urine output.