Chronic renal failure risk factors: Difference between revisions
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==Risk factors== | ==Risk factors== | ||
NSAID | *[[NSAID]]s | ||
===Age=== | ===Age=== | ||
* Age 65 or older | * Age 65 or older | ||
===Race=== | ===Race=== | ||
* African-American or | * African-American or Hispanic race | ||
===Family history=== | ===Family history=== | ||
* A positive family history | * A positive family history | ||
===Comorbidities=== | ===Comorbidities=== | ||
* [[Diabetes]] | * [[Diabetes]] | ||
* [[Hypertension]] | * [[Hypertension]] | ||
* [[Autoimmune diseases]] including [[SLE]], [[scleroderma]], and [[polyarteritis nodosa]] | * [[Autoimmune diseases]] including [[SLE]], [[scleroderma]], and [[polyarteritis nodosa]] | ||
* Multiple myeloma | * [[Multiple myeloma]] | ||
* Heart disease | * [[Heart disease]] | ||
* [[Smoking]] | * [[Smoking]] | ||
* [[Obesity]] | * [[Obesity]] | ||
| Line 28: | Line 28: | ||
===Genetics=== | ===Genetics=== | ||
* Certain [[DNA]] sequences like allelic versions of [[APOL1]] gene | * Certain [[DNA]] sequences like allelic versions of [[APOL1]] gene (associated with West African ancestry), contribute to a several fold higher risk of some etiologies of [[Chronic renal failure]] e.g [[focal segmental glomerulosclerosis]]. | ||
==References== | ==References== | ||
Revision as of 11:57, 14 November 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]
Overview
It is important to identify patients at risk for developing chronic renal disease, even in patients with a normal serum creatinine levels. Chronic renal failure, requiring dialysis or organ transplant, can often be prevented with early detection and treatment.
Risk factors
Age
- Age 65 or older
Race
- African-American or Hispanic race
Family history
- A positive family history
Comorbidities
- Diabetes
- Hypertension
- Autoimmune diseases including SLE, scleroderma, and polyarteritis nodosa
- Multiple myeloma
- Heart disease
- Smoking
- Obesity
- High cholesterol
Renal function
- Presence of proteinuria
- Abnormal urinary sediments
- Structural abnormalities of the urinary tract
- Past history of Acute renal failure
Genetics
- Certain DNA sequences like allelic versions of APOL1 gene (associated with West African ancestry), contribute to a several fold higher risk of some etiologies of Chronic renal failure e.g focal segmental glomerulosclerosis.