Ankylosing spondylitis risk factors: Difference between revisions

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Revision as of 21:44, 1 February 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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 ==Overview==
-Patients that possess the [[HLA-B27]] variant are at the highest risk for developing ankylosing spondylitis.
 ==Risk Factors==
-Variations of the HLA-B gene increase the risk of developing ankylosing spondylitis, although it is not a diagnostic test. Those with the [[HLA-B27]] variant are at highest risk of developing the disorder. HLA-B27, demonstrated in a [[blood test]], is occasionally used as a diagnostic, but does not distinguish AS from other diseases and is therefore not of real diagnostic value. Over 95% of people with AS are HLA-B27 positive, although this ratio varies from population to population (only 50% of African American patients with AS possess HLA-B27, and it is close to 80% among AS patients from Mediterranean countries).
+*
-Researches demonstrate the following factors may be associated with this disease.
-*Recent data demonstrate gene ARTS1 and IL23R are associated with ankylosing spondylitis.
-*Gender: Male
-*Age: 10~40 years old.
 ==References==