Sézary's disease: Difference between revisions

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{{SK}} Cutaneous T-cell lymphoma; mycosis fungoides; sezary syndrome
{{SK}} Cutaneous T-cell lymphoma; mycosis fungoides; sezary syndrome
==Overview==


'''Sézary's disease''' (or "Sézary syndrome") is a type of cutaneous [[lymphoma]] characterized by Albert Sézary. <ref>{{WhoNamedIt|synd|3594}}</ref>. "Sézary's cells" are [[T-cells]] that have pathological quantities of [[mucopolysaccharide]]s. Sézary's disease is sometimes considered a late stage of [[mycosis fungoides]]. Sezary syndrome and Mycosis Fungoides are T-cell lymphomas whose primary manifestation is in the skin.


==Etiology==


HTLV has thought to have been associated with both of the above cutaneous mycoses.
==Symptoms==
The hallmark symptoms for Sézary's disease are
# Generalized [[erythroderma]]
# [[Lymphadenopathy ]]
# Atypical T-cells ("Sezary cells") in the peripheral blood.
==Treatment==
[[Vorinostat]] '''(Zolinza®)''' is a second-line drug for CTCL. Treatments are often used in combination.
==References==
<references/>


==External links==
==External links==

Revision as of 15:29, 21 September 2012