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{{Underlinked|date=March 2014}}
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'''Nuclear ubiquitous casein and cyclin-dependent kinases substrate''' is a [[protein]] that in humans is encoded by the ''NUCKS1'' [[gene]].<ref name="pmid11298763">{{cite journal | vauthors = Ostvold AC, Norum JH, Mathiesen S, Wanvik B, Sefland I, Grundt K | title = Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo | journal = Eur J Biochem | volume = 268 | issue = 8 | pages = 2430–40 |date=Apr 2001 | pmid = 11298763 | pmc =  | doi =10.1046/j.1432-1327.2001.02120.x }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64710| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Nuclear casein kinase and cyclin-dependent kinase substrate 1
| HGNCid = 29923
| Symbol = NUCKS1
| AltSymbols =; FLJ21480; JC7; NUCKS
| OMIM = 
| ECnumber = 
| Homologene = 23377
| MGIid = 1934811
| GeneAtlas_image1 = PBB_GE_NUCKS1_217802_s_at_tn.png
| Function =
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process =  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 64710
    | Hs_Ensembl = ENSG00000069275
    | Hs_RefseqProtein = NP_073568
    | Hs_RefseqmRNA = NM_022731
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 203948570
    | Hs_GenLoc_end = 203986027
    | Hs_Uniprot = Q9H1E3
    | Mm_EntrezGene = 98415
    | Mm_Ensembl = ENSMUSG00000026434
    | Mm_RefseqmRNA = NM_175294
    | Mm_RefseqProtein = NP_780503
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 133738080
    | Mm_GenLoc_end = 133760518
    | Mm_Uniprot = Q80XU3
  }}
}}
'''Nuclear casein kinase and cyclin-dependent kinase substrate 1''', also known as '''NUCKS1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64710| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi= }}
*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
*{{cite journal  | author=Ostvold AC, Norum JH, Mathiesen S, ''et al.'' |title=Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo. |journal=Eur. J. Biochem. |volume=268 |issue= 8 |pages= 2430-40 |year= 2001 |pmid= 11298763 |doi= }}
*{{cite journal   |vauthors=Thompson HG, Harris JW, Wold BJ, etal |title=Identification and confirmation of a module of coexpressed genes. |journal=Genome Res. |volume=12 |issue= 10 |pages= 1517–22 |year= 2003 |pmid= 12368243 |doi= 10.1101/gr.418402 | pmc=187523 }}
*{{cite journal | author=Thompson HG, Harris JW, Wold BJ, ''et al.'' |title=Identification and confirmation of a module of coexpressed genes. |journal=Genome Res. |volume=12 |issue= 10 |pages= 1517-22 |year= 2003 |pmid= 12368243 |doi= 10.1101/gr.418402 }}
*{{cite journal   |vauthors=Grundt K, Skjeldal L, Anthonsen HW, etal |title=A putative DNA-binding domain in the NUCKS protein. |journal=Arch. Biochem. Biophys. |volume=407 |issue= 2 |pages= 168–75 |year= 2002 |pmid= 12413487 |doi=10.1016/S0003-9861(02)00513-1 }}
*{{cite journal | author=Grundt K, Skjeldal L, Anthonsen HW, ''et al.'' |title=A putative DNA-binding domain in the NUCKS protein. |journal=Arch. Biochem. Biophys. |volume=407 |issue= 2 |pages= 168-75 |year= 2002 |pmid= 12413487 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 }}
*{{cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
*{{cite journal   |vauthors=Ballif BA, Villén J, Beausoleil SA, etal |title=Phosphoproteomic analysis of the developing mouse brain. |journal=Mol. Cell. Proteomics |volume=3 |issue= 11 |pages= 1093–101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 }}
*{{cite journal | author=Ballif BA, Villén J, Beausoleil SA, ''et al.'' |title=Phosphoproteomic analysis of the developing mouse brain. |journal=Mol. Cell Proteomics |volume=3 |issue= 11 |pages= 1093-101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 }}
*{{cite journal   |vauthors=Grundt K, Haga IV, Aleporou-Marinou V, etal |title=Characterisation of the NUCKS gene on human chromosome 1q32.1 and the presence of a homologous gene in different species. |journal=Biochem. Biophys. Res. Commun. |volume=323 |issue= 3 |pages= 796–801 |year= 2004 |pmid= 15381070 |doi= 10.1016/j.bbrc.2004.08.153 }}
*{{cite journal | author=Grundt K, Haga IV, Aleporou-Marinou V, ''et al.'' |title=Characterisation of the NUCKS gene on human chromosome 1q32.1 and the presence of a homologous gene in different species. |journal=Biochem. Biophys. Res. Commun. |volume=323 |issue= 3 |pages= 796-801 |year= 2004 |pmid= 15381070 |doi= 10.1016/j.bbrc.2004.08.153 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gevaert K, Staes A, Van Damme J, etal |title=Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC. |journal=Proteomics |volume=5 |issue= 14 |pages= 3589–99 |year= 2006 |pmid= 16097034 |doi= 10.1002/pmic.200401217 }}
*{{cite journal | author=Gevaert K, Staes A, Van Damme J, ''et al.'' |title=Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC. |journal=Proteomics |volume=5 |issue= 14 |pages= 3589-99 |year= 2006 |pmid= 16097034 |doi= 10.1002/pmic.200401217 }}
*{{cite journal   |vauthors=Beausoleil SA, Villén J, Gerber SA, etal |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
*{{cite journal | author=Beausoleil SA, Villén J, Gerber SA, ''et al.'' |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285-92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | vauthors=Grundt K, Haga IV, Huitfeldt HS, Ostvold AC |title=Identification and characterization of two putative nuclear localization signals (NLS) in the DNA-binding protein NUCKS. |journal=Biochim. Biophys. Acta |volume=1773 |issue= 9 |pages= 1398–406 |year= 2007 |pmid= 17604136 |doi= 10.1016/j.bbamcr.2007.05.013 }}
*{{cite journal  | author=Grundt K, Haga IV, Huitfeldt HS, Ostvold AC |title=Identification and characterization of two putative nuclear localization signals (NLS) in the DNA-binding protein NUCKS. |journal=Biochim. Biophys. Acta |volume=1773 |issue= 9 |pages= 1398-406 |year= 2007 |pmid= 17604136 |doi= 10.1016/j.bbamcr.2007.05.013 }}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 13:19, 5 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Nuclear ubiquitous casein and cyclin-dependent kinases substrate is a protein that in humans is encoded by the NUCKS1 gene.[1][2]


References

  1. Ostvold AC, Norum JH, Mathiesen S, Wanvik B, Sefland I, Grundt K (Apr 2001). "Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo". Eur J Biochem. 268 (8): 2430–40. doi:10.1046/j.1432-1327.2001.02120.x. PMID 11298763.
  2. "Entrez Gene: NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1".

Further reading