Enteropathy-associated T-cell lymphoma natural history, complications and prognosis: Difference between revisions
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* Recurrences most frequent in the small intestine.<ref name=cancer.gov> Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 27, 2016</ref> | * Recurrences most frequent in the small intestine.<ref name=cancer.gov> Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 27, 2016</ref> | ||
* The most influential prognostic factor is bulky nature of disease, defined by a tumor mass greater than 5 cm. <ref name=pmid21566094>{{cite journal |vauthors=Delabie J, etal |title=Enteropathy-associated T-cell lymphoma: clinical and histological findings from the International Peripheral T-Cell Lymphoma Project|journal=Blood |volume=118|issue=148|pages= 148|date=July 2011 |doi=10.1182/blood-2011-02-335216}}</ref> <ref name="KumarBurger2016">{{cite journal|last1=Kumar|first1=A.|last2=Burger|first2=I. A.|last3=Zhang|first3=Z.|last4=Drill|first4=E. N.|last5=Migliacci|first5=J. C.|last6=Ng|first6=A.|last7=LaCasce|first7=A.|last8=Wall|first8=D.|last9=Witzig|first9=T. E.|last10=Ristow|first10=K.|last11=Yahalom|first11=J.|last12=Moskowitz|first12=C. H.|last13=Zelenetz|first13=A. D.|title=Definition of bulky disease in early stage Hodgkin lymphoma in computed tomography era: prognostic significance of measurements in the coronal and transverse planes|journal=Haematologica|volume=101|issue=10|year=2016|pages=1237–1243|issn=0390-6078|doi=10.3324/haematol.2016.141846}}</ref> | * The most influential prognostic factor is bulky nature of disease, defined by a tumor mass greater than 5 cm. <ref name=pmid21566094>{{cite journal |vauthors=Delabie J, etal |title=Enteropathy-associated T-cell lymphoma: clinical and histological findings from the International Peripheral T-Cell Lymphoma Project|journal=Blood |volume=118|issue=148|pages= 148|date=July 2011 |doi=10.1182/blood-2011-02-335216}}</ref> <ref name="KumarBurger2016">{{cite journal|last1=Kumar|first1=A.|last2=Burger|first2=I. A.|last3=Zhang|first3=Z.|last4=Drill|first4=E. N.|last5=Migliacci|first5=J. C.|last6=Ng|first6=A.|last7=LaCasce|first7=A.|last8=Wall|first8=D.|last9=Witzig|first9=T. E.|last10=Ristow|first10=K.|last11=Yahalom|first11=J.|last12=Moskowitz|first12=C. H.|last13=Zelenetz|first13=A. D.|title=Definition of bulky disease in early stage Hodgkin lymphoma in computed tomography era: prognostic significance of measurements in the coronal and transverse planes|journal=Haematologica|volume=101|issue=10|year=2016|pages=1237–1243|issn=0390-6078|doi=10.3324/haematol.2016.141846}}</ref> | ||
* [[Autologous stem cell transplantation]] is | * [[Autologous stem cell transplantation]] is a useful way of treatment for selected patients with enteropathy-associated T-cell lymphoma and can control disease progress. | ||
==References== | ==References== |
Revision as of 20:30, 18 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Enteropathy-associated T-cell lymphoma is usually a fast-growing (aggressive) lymphoma. Common complications of enteropathy-associated T-cell lymphoma include ulcer, obstruction, and perforation of small intestine.[1]Prognosis is generally poor.
Natural History
- Enteropathy-associated T-cell lymphoma is usually a fast-growing (aggressive) lymphoma.[1]
- It is associated with celiac disease (sprue).
- Most adults are diagnosed with celiac disease at the same time as their lymphoma or shortly before their lymphoma is diagnosed.
- Enteropathy-associated T-cell lymphoma may spread to the liver, spleen, lymph nodes, gallbladder, stomach, colon or skin.
Complications
- Common complications of enteropathy-associated T-cell lymphoma include:[1]
- Ulcer in small intestine
- Obstruction of small intestine
- Perforation of small intestine
Prognosis
- The prognosis for people with enteropathy-associated T-cell lymphoma is often not very good.[1]
- Recurrences most frequent in the small intestine.[2]
- The most influential prognostic factor is bulky nature of disease, defined by a tumor mass greater than 5 cm. [3] [4]
- Autologous stem cell transplantation is a useful way of treatment for selected patients with enteropathy-associated T-cell lymphoma and can control disease progress.
References
- ↑ 1.0 1.1 1.2 1.3 Enteropathy-associated T-cell lymphoma . Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/enteropathy-associated-t-cell-lymphoma/?region=on Accessed on January 27, 2016
- ↑ Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 27, 2016
- ↑ Delabie J, et al. (July 2011). "Enteropathy-associated T-cell lymphoma: clinical and histological findings from the International Peripheral T-Cell Lymphoma Project". Blood. 118 (148): 148. doi:10.1182/blood-2011-02-335216.
- ↑ Kumar, A.; Burger, I. A.; Zhang, Z.; Drill, E. N.; Migliacci, J. C.; Ng, A.; LaCasce, A.; Wall, D.; Witzig, T. E.; Ristow, K.; Yahalom, J.; Moskowitz, C. H.; Zelenetz, A. D. (2016). "Definition of bulky disease in early stage Hodgkin lymphoma in computed tomography era: prognostic significance of measurements in the coronal and transverse planes". Haematologica. 101 (10): 1237–1243. doi:10.3324/haematol.2016.141846. ISSN 0390-6078.