Ileus medical therapy: Difference between revisions

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==Medical Therapy==
==Medical Therapy==
Medical therapy for ileus includes correcting the underlying condition and supportive therapy.<ref name="pmid26703957">{{cite journal |vauthors=Bruns BR, Kozar RA |title=Feeding the Postoperative Patient on Vasopressor Support: Feeding and Pressor Support |journal=Nutr Clin Pract |volume=31 |issue=1 |pages=14–7 |year=2016 |pmid=26703957 |doi=10.1177/0884533615619932 |url=}}</ref><ref name="pmid10696888">{{cite journal |vauthors=Cali RL, Meade PG, Swanson MS, Freeman C |title=Effect of Morphine and incision length on bowel function after colectomy |journal=Dis. Colon Rectum |volume=43 |issue=2 |pages=163–8 |year=2000 |pmid=10696888 |doi= |url=}}</ref><ref name="pmid25503902">{{cite journal |vauthors=Wu Z, Boersema GS, Dereci A, Menon AG, Jeekel J, Lange JF |title=Clinical endpoint, early detection, and differential diagnosis of postoperative ileus: a systematic review of the literature |journal=Eur Surg Res |volume=54 |issue=3-4 |pages=127–38 |year=2015 |pmid=25503902 |doi=10.1159/000369529 |url=}}</ref>  
Medical therapy for ileus includes correcting the underlying condition and supportive therapy.<ref name="pmid26703957">{{cite journal |vauthors=Bruns BR, Kozar RA |title=Feeding the Postoperative Patient on Vasopressor Support: Feeding and Pressor Support |journal=Nutr Clin Pract |volume=31 |issue=1 |pages=14–7 |year=2016 |pmid=26703957 |doi=10.1177/0884533615619932 |url=}}</ref><ref name="pmid10696888">{{cite journal |vauthors=Cali RL, Meade PG, Swanson MS, Freeman C |title=Effect of Morphine and incision length on bowel function after colectomy |journal=Dis. Colon Rectum |volume=43 |issue=2 |pages=163–8 |year=2000 |pmid=10696888 |doi= |url=}}</ref><ref name="pmid25503902">{{cite journal |vauthors=Wu Z, Boersema GS, Dereci A, Menon AG, Jeekel J, Lange JF |title=Clinical endpoint, early detection, and differential diagnosis of postoperative ileus: a systematic review of the literature |journal=Eur Surg Res |volume=54 |issue=3-4 |pages=127–38 |year=2015 |pmid=25503902 |doi=10.1159/000369529 |url=}}</ref>  
*Patients should receive intravenous hydration.
*Patients of ileus from electrolyte abnormalities should be treated with appropriate supplementation.
*Patients of ileus from electrolyte abnormalities should be treated with appropriate supplementation.
*Bowel rest and nasogastric decompression can relieve recurrent vomiting or abdominal distention associated with pain.
*Antimotility drugs and other medications (narcotics) which may alter intestinal motility should be stopped.  
*Antimotility drugs and other medications (narcotics) which may alter intestinal motility should be stopped.  
*Bowel rest and nasogastric decompression can relieve recurrent vomiting or abdominal distention associated with pain.
*Prokinetic agents such as erythromycin are not routinely recommended.
*Prokinetic agents such as erythromycin are not routinely recommended.
*Patients should receive intravenous hydration.
===Contraindicated medications===
===Contraindicated medications===
{{MedCondContrAbs
{{MedCondContrAbs

Revision as of 22:36, 31 January 2018

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Overview

Nil per os (NPO or Nothing by Mouth) is mandatory in all cases. Nasogastric suction and parenteral feeds may be required until passage is restored. There are several options in the case of paralytic ileus. Most treatment is supportive. If caused by medication, the offending agent is discontinued or reduced. Bowel movements may be stimulated by prescribing lactulose, erythromycin or in severe cases, (Ogilvie's syndrome) neostigmine. If possible the underlying cause is corrected (e.g. replace electrolytes).

Medical Therapy

Medical therapy for ileus includes correcting the underlying condition and supportive therapy.[1][2][3]

  • Patients should receive intravenous hydration.
  • Patients of ileus from electrolyte abnormalities should be treated with appropriate supplementation.
  • Bowel rest and nasogastric decompression can relieve recurrent vomiting or abdominal distention associated with pain.
  • Antimotility drugs and other medications (narcotics) which may alter intestinal motility should be stopped.
  • Prokinetic agents such as erythromycin are not routinely recommended.

Contraindicated medications

Paralytic ileus is considered an absolute contraindication to the use of the following medications:

References

  1. Bruns BR, Kozar RA (2016). "Feeding the Postoperative Patient on Vasopressor Support: Feeding and Pressor Support". Nutr Clin Pract. 31 (1): 14–7. doi:10.1177/0884533615619932. PMID 26703957.
  2. Cali RL, Meade PG, Swanson MS, Freeman C (2000). "Effect of Morphine and incision length on bowel function after colectomy". Dis. Colon Rectum. 43 (2): 163–8. PMID 10696888.
  3. Wu Z, Boersema GS, Dereci A, Menon AG, Jeekel J, Lange JF (2015). "Clinical endpoint, early detection, and differential diagnosis of postoperative ileus: a systematic review of the literature". Eur Surg Res. 54 (3–4): 127–38. doi:10.1159/000369529. PMID 25503902.