As a [[sedative]] when used as premedication and following general [[anesthesia]], Hydroxyzine may potentiate [[meperidine]] (Demerol®) and [[barbiturates]], so their use in pre-anesthetic adjunctive therapy should be modified on an individual basis. Atropine and other [[belladonna]] alkaloids are not affected by the drug. Hydroxyzine is not known to interfere with the action of digitalis in any way and it may be used concurrently with this agent.
As a [[sedative]] when used as premedication and following general [[anesthesia]], Hydroxyzine may potentiate [[meperidine]] (Demerol®) and [[barbiturates]], so their use in pre-anesthetic adjunctive therapy should be modified on an individual basis. Atropine and other [[belladonna]] alkaloids are not affected by the drug. Hydroxyzine is not known to interfere with the action of digitalis in any way and it may be used concurrently with this agent.
The effectiveness of hydroxyzine as an antianxiety agent for long term use, that is more than 4 months, has not been assessed by systematic clinical studies. The physician should reassess periodically the usefulness of the drug for the individual patient.
The effectiveness of hydroxyzine as an antianxiety agent for long term use, that is more than 4 months, has not been assessed by systematic clinical studies. The physician should reassess periodically the usefulness of the drug for the individual patient
|adverseReactions=[[xerostomia]], [[headache]], and [[somnolence]].
|adverseReactions=[[xerostomia]], [[headache]], and [[somnolence]].
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Overview
Hydroxyzine (oral) is an antianxiety, antiemetic, central nervous system agent that is FDA approved for the treatment of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested.
As a sedative when used as premedication and following general anesthesia, Hydroxyzine may potentiate meperidine (Demerol®) and barbiturates, so their use in pre-anesthetic adjunctive therapy should be modified on an individual basis. Atropine and other belladonna alkaloids are not affected by the drug. Hydroxyzine is not known to interfere with the action of digitalis in any way and it may be used concurrently with this agent.
The effectiveness of hydroxyzine as an antianxiety agent for long term use, that is more than 4 months, has not been assessed by systematic clinical studies. The physician should reassess periodically the usefulness of the drug for the individual patient. Common adverse reactions include xerostomia, headache, and somnolence..
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
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Off-Label Use and Dosage (Adult)
Guideline-Supported Use
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There is limited information regarding Off-Label Guideline-Supported Use of Hydroxyzine (oral) in adult patients.
Non–Guideline-Supported Use
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There is limited information regarding Off-Label Non–Guideline-Supported Use of Hydroxyzine (oral) in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
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There is limited information regarding FDA-Labeled Use of Hydroxyzine (oral) in pediatric patients.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
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Developed by:
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Condition2
There is limited information regarding Off-Label Guideline-Supported Use of Hydroxyzine (oral) in pediatric patients.
Non–Guideline-Supported Use
Condition1
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Condition2
There is limited information regarding Off-Label Non–Guideline-Supported Use of Hydroxyzine (oral) in pediatric patients.
Contraindications
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Clinical Trials Experience
There is limited information regarding Clinical Trial Experience of Hydroxyzine (oral) in the drug label.
Body as a Whole
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Digestive
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Musculoskeletal
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Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous
Postmarketing Experience
There is limited information regarding Postmarketing Experience of Hydroxyzine (oral) in the drug label.