Malaria laboratory findings: Difference between revisions

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Revision as of 20:04, 24 July 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Laboratory Findings

Whenever possible, the diagnosis of malaria should always be confirmed by laboratory tests. These should include:

Specific diagnostic tests for malaria
Laboratory workup

References

Template:WH Template:WS

@@ Line 7: / Line 7: @@
 ==Laboratory Findings==
 Whenever possible, the diagnosis of malaria should always be confirmed by laboratory tests. These should include:
+* Specific diagnostic tests for malaria
+* Laboratory workup
 <!--
+, , and and increases in lactic dehydrogenase may be marked with large P. falciparum parasite burdens.
+Microcytosis may be seen in patients from malaria-endemic areas but is often due to iron deficiency or thalassemia.
+Leukocyte counts may be high, normal, or low.
+Platelet counts may be normal or slightly low but have been observed to be <70,000/μL in P. falciparum infection398 and occasion- ally in P. vivax infection.
+Sodium may be slightly low, possibly owing to syndrome of inappropriate antidiuretic hormone, excessive vomiting, or urinary losses.
+Acidemia (pH less than 7.35), acidosis (bicarbonate < 15 mmol/L), and lactate levels >5 mmol/L can be seen in severe P. falciparum malaria (see later).
+Some degree of renal impairment is common in falciparum malaria and may be associated with increased creatinine, proteinuria, and hemoglobinuria.
+Serum glucose is often low in children with falciparum malaria, but it is commonly normal in adults.
+In children with severe falciparum malaria, bacteremia/sepsis may be present at the time of initial clinical evalua-tion and blood cultures may be positive.402,403
 ==Laboratory Findings==
 The table below displays the nonspecific laboratory abnormalities associated with Ebola infection, including:<ref name="pmid21084112">{{cite journal| author=Feldmann H, Geisbert TW| title=Ebola haemorrhagic fever. | journal=Lancet | year= 2011 | volume= 377 | issue= 9768 | pages= 849-62 | pmid=21084112 | doi=10.1016/S0140-6736(10)60667-8 | pmc=PMC3406178 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21084112  }} </ref>
@@ Line 17: / Line 42: @@
 ! style="width: 75px; background: #4479BA; text-align: center;"|{{fontcolor|#FFF|Test}}
 ! style="width: 200px; background: #4479BA; text-align: center;"| {{fontcolor|#FFF|Findings}}
+|-
+| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Complete Blood Count]] count'''
+| style="background: #DCDCDC; padding: 5px;"| Decreased [[Hemoglobin]]<br>Decreased [[Hematocrit]]<br>Decreased [[Haptoglobin]]<br>[[Microcytosis]]
 |-
 | style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[White blood cell]] count'''
-| style="background: #DCDCDC; padding: 5px;"| [[Leucopenia]]<br>[[Lymphopenia]]<br>[[Neutrophilia]]
+| style="background: #DCDCDC; padding: 5px;"| Increased or Decreased [[Leukocyte Count]]
 |-
-| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Blood smear]]'''
+| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Biochemistry]]'''
-| style="background: #DCDCDC; padding: 5px;"| [[Left shift]]<br>Atypical [[lymphocytes]]
+| style="background: #DCDCDC; padding: 5px;"| [[Hypoglycemia]]<br>Increased [[LDH]]<br>Possible [[Hyponatremia]]<br> Acidosis: High [[Lactate]]; Low [[Bicarbonate]]
 |-
 | style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Coagulation]]'''
-| style="background: #DCDCDC; padding: 5px;"| Consumption of [[clotting factors]]<br>Increased concentrations of [[fibrin degradation products]]<br>
+| style="background: #DCDCDC; padding: 5px;"| [[Thrombocytopenia]]
 |-
 | style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Liver function tests]]'''
-| style="background: #DCDCDC; padding: 5px;"| Raised [[aspartate aminotransferase]]<br>Raised [[alanine aminotransferase]]<br>Extended [[prothrombin time]]<br>Extended [[partial thromboplastin time]]
+| style="background: #DCDCDC; padding: 5px;"| Raised [[]]<br>[[]]<br>[[]]<br>[[]]
-|-
-| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Proteins]]'''
-| style="background: #DCDCDC; padding: 5px;"| [[Hyperproteinemia]]
 |-
 | style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Urinalysis]]'''
-| style="background: #DCDCDC; padding: 5px;"| [[Proteinuria]]
+| style="background: #DCDCDC; padding: 5px;"| [[Proteinuria]]<br>[[Hemoglobinuria]]
 |}

Malaria laboratory findings: Difference between revisions

Revision as of 20:04, 24 July 2014

Overview

Laboratory Findings

References

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