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| {{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.D.]] [mailto:psingh@perfuse.org]
| | #redirect[[Hospital-acquired pneumonia pathophysiology#Ventilator-associated Pneumonia]] |
| {{Ventilator-associated pneumonia}}
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| ==Overview==
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| == Pathophysiology ==
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| [[Ventilator-associated pneumonia]] is primarily caused by the [[endotracheal]] or [[tracheostomy]] tube allows free passage of bacteria into the lower segments of the lung in a person who often has underlying lung or immune problems. Bacteria travel in small [[droplet]]s both through the endotracheal tube and around the cuff. Often, bacteria colonize the endotracheal or tracheostomy tube and are [[Embolism|embolized]] into the lungs with each breath. Bacteria may also be brought down into the lungs with procedures such as deep suctioning or [[bronchoscopy]]. Whether bacteria also travel from the [[sinuses]] or the stomach into the lungs is, controversial. However, spread to the lungs from the [[blood stream]] or the [[gut]] is uncommon.
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| Once inside the lungs, bacteria then take advantage of any deficiencies in the [[immune system]] (such as due to malnutrition or chemotherapy) and multiply. A combination of bacterial damage and consequences of the immune response lead to disruption of [[gas exchange]] with resulting symptoms.
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| ==References==
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| {{reflist|2}}
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| [[Category:Diseaase]]
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| [[Category:Pulmonology]]
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| [[Category:Infectious disease]]
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| [[Category:Pneumonia|Pneumonia]]
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| [[Category:Emergency medicine]]
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| {{WH}}
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| {{WS}}
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