WD repeat-containing protein 77: Difference between revisions

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{{Infobox_gene}}
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'''Methylosome protein 50''' is a [[protein]] that in humans is encoded by the ''WDR77'' [[gene]].<ref name="pmid11756452">{{cite journal |vauthors=Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G | title = A novel WD repeat protein component of the methylosome binds Sm proteins | journal = J Biol Chem | volume = 277 | issue = 10 | pages = 8243–7 |date=Mar 2002 | pmid = 11756452 | pmc =  | doi = 10.1074/jbc.M109984200 }}</ref><ref name="pmid8619474">{{cite journal |vauthors=Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Anal Biochem | volume = 236 | issue = 1 | pages = 107–13 |date=Jun 1996 | pmid = 8619474 | pmc =  | doi = 10.1006/abio.1996.0138 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: WDR77 WD repeat domain 77| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79084| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = WD repeat domain 77
| HGNCid = 29652
| Symbol = WDR77
| AltSymbols =; HKMT1069; MEP50; MGC2722; Nbla10071; RP11-552M11.3
| OMIM =
| ECnumber =
| Homologene = 11466
| MGIid = 1917715
  | GeneAtlas_image1 = PBB_GE_WDR77_201420_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_WDR77_201421_s_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}}  
| Component =
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 79084
    | Hs_Ensembl = ENSG00000116455
    | Hs_RefseqProtein = NP_077007
    | Hs_RefseqmRNA = NM_024102
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 111784035
    | Hs_GenLoc_end = 111793521
    | Hs_Uniprot = Q9BQA1
    | Mm_EntrezGene = 70465
    | Mm_Ensembl = ENSMUSG00000000561
    | Mm_RefseqmRNA = NM_027432
    | Mm_RefseqProtein = NP_081708
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 3
    | Mm_GenLoc_start = 106087554
    | Mm_GenLoc_end = 106097816
    | Mm_Uniprot = Q3V2T0
  }}
}}
'''WD repeat domain 77''', also known as '''WDR77''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: WDR77 WD repeat domain 77| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79084| accessdate = }}</ref>


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| summary_text =  
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==Interactions==
WD repeat-containing protein 77 has been shown to [[Protein-protein interaction|interact]] with [[CTDP1]]<ref name=pmid12560496>{{cite journal |doi=10.1093/nar/gkg197 |last=Licciardo |first=Paolo |authorlink= |author2=Amente Stefano |author3=Ruggiero Luca |author4=Monti Maria |author5=Pucci Piero |author6=Lania Luigi |author7=Majello Barbara  |date=Feb 2003 |title=The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP |journal=Nucleic Acids Res. |volume=31 |issue=3 |pages=999–1005 |publisher= |location = England| issn = | pmid = 12560496 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=149217 }}</ref> and [[Protein arginine methyltransferase 5]].<ref name=pmid11756452 />


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
*{{cite journal  | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal   |vauthors=Yu W, Andersson B, Worley KC, etal |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi= 10.1101/gr.7.4.353| pmc=139146 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi=  }}
*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }}
*{{cite journal  | author=Friesen WJ, Wyce A, Paushkin S, ''et al.'' |title=A novel WD repeat protein component of the methylosome binds Sm proteins. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 8243-7 |year= 2002 |pmid= 11756452 |doi= 10.1074/jbc.M109984200 }}
*{{cite journal   |vauthors=Licciardo P, Amente S, Ruggiero L, etal |title=The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP. |journal=Nucleic Acids Res. |volume=31 |issue= 3 |pages= 999–1005 |year= 2003 |pmid= 12560496 |doi=10.1093/nar/gkg197  | pmc=149217 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Licciardo P, Amente S, Ruggiero L, ''et al.'' |title=The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP. |journal=Nucleic Acids Res. |volume=31 |issue= 3 |pages= 999-1005 |year= 2003 |pmid= 12560496 |doi=  }}
*{{cite journal   |vauthors=Yamada S, Ohira M, Horie H, etal |title=Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. |journal=Oncogene |volume=23 |issue= 35 |pages= 5901–11 |year= 2004 |pmid= 15221005 |doi= 10.1038/sj.onc.1207782 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Jin J, Smith FD, Stark C, etal |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 }}
*{{cite journal | author=Yamada S, Ohira M, Horie H, ''et al.'' |title=Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. |journal=Oncogene |volume=23 |issue= 35 |pages= 5901-11 |year= 2004 |pmid= 15221005 |doi= 10.1038/sj.onc.1207782 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Jin J, Smith FD, Stark C, ''et al.'' |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436-50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 }}
*{{cite journal   |vauthors=Amente S, Napolitano G, Licciardo P, etal |title=Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation. |journal=FEBS Lett. |volume=579 |issue= 3 |pages= 683–9 |year= 2005 |pmid= 15670829 |doi= 10.1016/j.febslet.2004.12.045 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gregory SG, Barlow KF, McLay KE, etal |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 |bibcode=2006Natur.441..315G }}
*{{cite journal | author=Amente S, Napolitano G, Licciardo P, ''et al.'' |title=Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation. |journal=FEBS Lett. |volume=579 |issue= 3 |pages= 683-9 |year= 2005 |pmid= 15670829 |doi= 10.1016/j.febslet.2004.12.045 }}
*{{cite journal   |vauthors=Furuno K, Masatsugu T, Sonoda M, etal |title=Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively in vitro. |journal=Biochem. Biophys. Res. Commun. |volume=345 |issue= 3 |pages= 1051–8 |year= 2006 |pmid= 16712789 |doi= 10.1016/j.bbrc.2006.05.014 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal  |vauthors=Zhou L, Wu H, Lee P, Wang Z |title=Roles of the androgen receptor cofactor p44 in the growth of prostate epithelial cells. |journal=J. Mol. Endocrinol. |volume=37 |issue= 2 |pages= 283–300 |year= 2007 |pmid= 17032745 |doi= 10.1677/jme.1.02062 }}
*{{cite journal | author=Furuno K, Masatsugu T, Sonoda M, ''et al.'' |title=Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively in vitro. |journal=Biochem. Biophys. Res. Commun. |volume=345 |issue= 3 |pages= 1051-8 |year= 2006 |pmid= 16712789 |doi= 10.1016/j.bbrc.2006.05.014 }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | author=Zhou L, Wu H, Lee P, Wang Z |title=Roles of the androgen receptor cofactor p44 in the growth of prostate epithelial cells. |journal=J. Mol. Endocrinol. |volume=37 |issue= 2 |pages= 283-300 |year= 2007 |pmid= 17032745 |doi= 10.1677/jme.1.02062 }}
*{{cite journal   |vauthors=Liang JJ, Wang Z, Chiriboga L, etal |title=The expression and function of androgen receptor coactivator p44 and protein arginine methyltransferase 5 in the developing testis and testicular tumors. |journal=J. Urol. |volume=177 |issue= 5 |pages= 1918–22 |year= 2007 |pmid= 17437848 |doi= 10.1016/j.juro.2007.01.017 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Liang JJ, Wang Z, Chiriboga L, ''et al.'' |title=The expression and function of androgen receptor coactivator p44 and protein arginine methyltransferase 5 in the developing testis and testicular tumors. |journal=J. Urol. |volume=177 |issue= 5 |pages= 1918-22 |year= 2007 |pmid= 17437848 |doi= 10.1016/j.juro.2007.01.017 }}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 00:49, 27 June 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Methylosome protein 50 is a protein that in humans is encoded by the WDR77 gene.[1][2][3]


Interactions

WD repeat-containing protein 77 has been shown to interact with CTDP1[4] and Protein arginine methyltransferase 5.[1]

References

  1. ↑ 1.0 1.1 Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G (Mar 2002). "A novel WD repeat protein component of the methylosome binds Sm proteins". J Biol Chem. 277 (10): 8243–7. doi:10.1074/jbc.M109984200. PMID 11756452.
  2. ↑ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
  3. ↑ "Entrez Gene: WDR77 WD repeat domain 77".
  4. ↑ Licciardo, Paolo; Amente Stefano; Ruggiero Luca; Monti Maria; Pucci Piero; Lania Luigi; Majello Barbara (Feb 2003). "The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP". Nucleic Acids Res. England. 31 (3): 999–1005. doi:10.1093/nar/gkg197. PMC 149217. PMID 12560496.

Further reading



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