| ==ACC/AHA Guidelines- Cardiac Resynchronization (DO NOT EDIT)<ref name="pmid18483207">{{cite journal |author=Epstein AE, DiMarco JP, Ellenbogen KA, Estes NA, Freedman RA, Gettes LS, Gillinov AM, Gregoratos G, Hammill SC, Hayes DL, Hlatky MA, Newby LK, Page RL, Schoenfeld MH, Silka MJ, Stevenson LW, Sweeney MO, Smith SC, Jacobs AK, Adams CD, Anderson JL, Buller CE, Creager MA, Ettinger SM, Faxon DP, Halperin JL, Hiratzka LF, Hunt SA, Krumholz HM, Kushner FG, Lytle BW, Nishimura RA, Ornato JP, Page RL, Riegel B, Tarkington LG, Yancy CW |title=ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices): developed in collaboration with the American Association for Thoracic Surgery and Society of Thoracic Surgeons |journal=[[Circulation]] |volume=117 |issue=21 |pages=e350–408 |year=2008 |month=May |pmid=18483207 |doi=10.1161/CIRCUALTIONAHA.108.189742 |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=18483207 |issn= |accessdate=2011-01-15}}</ref>==
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| '''1.''' Patients with [[left ventricular ejection fraction]] ([[LVEF]]) of less than or equal to 35%, sinus rhythm, and [[New york heart association functional classification|NYHA functional class III or ambulatory class IV]] symptoms despite recommended, optimal medical therapy and who have cardiac dyssynchrony, which is currently defined as a QRS duration greater than or equal to 0.12 seconds, should receive [[cardiac resynchronization therapy]], with or without an [[implantable cardioverter defibrillator]] ([[ICD]]), unless contraindicated.<ref name="pmid17986493">{{cite journal |author=Beshai JF, Grimm RA, Nagueh SF, Baker JH, Beau SL, Greenberg SM, Pires LA, Tchou PJ |title=Cardiac-resynchronization therapy in heart failure with narrow QRS complexes |journal=[[The New England Journal of Medicine]] |volume=357 |issue=24 |pages=2461–71 |year=2007 |month=December |pmid=17986493 |doi=10.1056/NEJMoa0706695 |url=http://dx.doi.org/10.1056/NEJMoa0706695 |accessdate=2012-04-05}}</ref><ref 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|journal=[[Circulation]] |volume=99 |issue=12 |pages=1567–73 |year=1999 |month=March |pmid=10096932 |doi= |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=10096932 |accessdate=2012-04-05}}</ref><ref name="pmid11139911">{{cite journal |author=Toussaint JF, Lavergne T, Ollitraut J, Hignette C, Darondel JM, De Dieuleveult B, Froissart M, Le Heuzey JY, Guize L, Paillard M |title=Biventricular pacing in severe heart failure patients reverses electromechanical dyssynchronization from apex to base |journal=[[Pacing and Clinical Electrophysiology : PACE]] |volume=23 |issue=11 Pt 2 |pages=1731–4 |year=2000 |month=November |pmid=11139911 |doi= |url= |accessdate=2012-04-05}}</ref><ref name="pmid11120694">{{cite journal |author=Nelson GS, Berger RD, Fetics BJ, Talbot M, Spinelli JC, Hare JM, Kass DA |title=Left ventricular or biventricular pacing improves cardiac function at diminished energy cost in patients with dilated cardiomyopathy and left bundle-branch block |journal=[[Circulation]] |volume=102 |issue=25 |pages=3053–9 |year=2000 |month=December |pmid=11120694 |doi= |url=http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=11120694 |accessdate=2012-04-05}}</ref><ref name="pmid12063368">{{cite journal |author=Abraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E, Kocovic DZ, Packer M, Clavell AL, Hayes DL, Ellestad M, Trupp RJ, Underwood J, Pickering F, Truex C, McAtee P, Messenger J |title=Cardiac resynchronization in chronic heart failure |journal=[[The New England Journal of Medicine]] |volume=346 |issue=24 |pages=1845–53 |year=2002 |month=June |pmid=12063368 |doi=10.1056/NEJMoa013168 |url=http://dx.doi.org/10.1056/NEJMoa013168 |accessdate=2012-04-05}}</ref><ref name="pmid12771115">{{cite journal |author=Young JB, Abraham WT, Smith AL, Leon AR, Lieberman R, Wilkoff B, Canby RC, Schroeder JS, Liem LB, Hall S, Wheelan K |title=Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial |journal=[[JAMA : the Journal of the American Medical Association]] |volume=289 |issue=20 |pages=2685–94 |year=2003 |month=May |pmid=12771115 |doi=10.1001/jama.289.20.2685 |url=http://jama.ama-assn.org/cgi/pmidlookup?view=long&pmid=12771115 |accessdate=2012-04-05}}</ref><ref name="pmid15312864">{{cite journal |author=McAlister FA, Stewart S, Ferrua S, McMurray JJ |title=Multidisciplinary strategies for the management of heart failure patients at high risk for admission: a systematic review of randomized trials |journal=[[Journal of the American College of Cardiology]] |volume=44 |issue=4 |pages=810–9 |year=2004 |month=August |pmid=15312864 |doi=10.1016/j.jacc.2004.05.055 |url=http://linkinghub.elsevier.com/retrieve/pii/S0735-1097(04)01123-4 |accessdate=2012-04-05}}</ref><ref name="pmid15152059">{{cite journal |author=Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T, Carson P, DiCarlo L, DeMets D, White BG, DeVries DW, Feldman AM |title=Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure |journal=[[The New England Journal of Medicine]] |volume=350 |issue=21 |pages=2140–50 |year=2004 |month=May |pmid=15152059 |doi=10.1056/NEJMoa032423 |url=http://dx.doi.org/10.1056/NEJMoa032423 |accessdate=2012-04-05}}</ref><ref name="pmid12419298">{{cite journal |author=Leclercq C, Walker S, Linde C, Clementy J, Marshall AJ, Ritter P, Djiane P, Mabo P, Levy T, Gadler F, Bailleul C, Daubert JC |title=Comparative effects of permanent biventricular and right-univentricular pacing in heart failure patients with chronic atrial fibrillation |journal=[[European Heart Journal]] |volume=23 |issue=22 |pages=1780–7 |year=2002 |month=November |pmid=12419298 |doi= |url= |accessdate=2012-04-05}}</ref><ref name="pmid11955841">{{cite journal |author=Leon AR, Greenberg JM, Kanuru N, Baker CM, Mera FV, Smith AL, Langberg JJ, DeLurgio DB |title=Cardiac resynchronization in patients with congestive heart failure and chronic atrial fibrillation: effect of upgrading to biventricular pacing after chronic right ventricular pacing |journal=[[Journal of the American College of Cardiology]] |volume=39 |issue=8 |pages=1258–63 |year=2002 |month=April |pmid=11955841 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0735109702017795 |accessdate=2012-04-05}}</ref> ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: A]])''
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