Familial amyloidosis CT scan: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Familial amyloidosis}} | {{Familial amyloidosis}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{Fs}}, {{sab}} | ||
==Overview== | ==Overview== | ||
[[CT scan]] may be helpful in the [[diagnosis]] of familial amyloidosis. [[Computed tomography|CT scan]] can be done to assess for amyloid deposition in particular organs. It can also be done to rule out other [[causes]] of [[Organ (anatomy)|organ]] dysfunction. Findings on [[liver]] [[CT scan]] suggestive of familial amyloidosis include [[liver enlargement]] with [[heterogeneous]] decreased attenuation, asymmetric and triangular [[hepatomegaly]] with the apex at the [[falciform ligament]], and [[Parenchyma|parenchymal]] [[calcification]]. Findings on [[Kidney|renal]] [[CT scan]] suggestive of familial amyloidosis include [[kidney]] enlargement with [[heterogeneous]] decreased attenuation, and [[Parenchyma|parenchymal]] [[calcification]]. Findings on [[cardiac]] [[CT scan]] suggestive of familial amyloidosis include [[heart enlargement]] with [[heterogeneous]] decreased attenuation, [[cardiac]] [[calcification]], and [[pericardial effusion]]. | |||
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==CT scan== | ==CT scan== | ||
In [[Liver|hepatic]] amyloidosis, [[Computed tomography|CT scan]] findings may include: | |||
*[[Liver]] enlargement with [[heterogeneous]] decreased attenuation | |||
* Asymmetric and triangular [[hepatomegaly]] with the apex at the [[falciform ligament]] (due to mild [[Atrophy|atrophic]] change of the lateral border of both [[Liver|hepatic]] lobes) | |||
*[[Parenchyma|Parenchymal]] [[calcification]] (rare) | |||
In [[Kidney|renal]] amyloidosis, [[Computed tomography|CT scan]] findings may include: | |||
*[[Kidney]] enlargement with [[heterogeneous]] decreased attenuation | |||
*[[Parenchyma|Parenchymal]] [[calcification]] (rare) | |||
[ | |||
*[ | |||
*[ | |||
In [[cardiac amyloidosis]], [[Computed tomography|CT scan]] findings may include<ref name="pmid24847009">{{cite journal| author=Falk RH, Quarta CC, Dorbala S| title=How to image cardiac amyloidosis. | journal=Circ Cardiovasc Imaging | year= 2014 | volume= 7 | issue= 3 | pages= 552-62 | pmid=24847009 | doi=10.1161/CIRCIMAGING.113.001396 | pmc=4118308 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24847009 }} </ref>: | |||
*[ | *[[Heart]] enlargement with [[heterogeneous]] decreased attenuation | ||
*[ | *[[Heart|Cardiac]] [[Calcification|calcifications]] | ||
*[ | *[[Pericardial effusion]] (rare) | ||
===Images=== | |||
[[File:Amyloidoma-mediastinal-1.jpg|300px|left|thumb| CT image showing mediastinal amyloidosis (yellow arrows). Case courtesy of Dr Natalie Yang, Radiopaedia.org, rID: 6711]] | |||
[[File:Amyloidosis-bronchial-and-diffuse-nodular-pulmonary-involvement.jpg|300px|center|thumb| Amyloidosis - bronchial and diffuse nodular pulmonary involvement. Case courtesy of Dr Bruno Di Muzio, Radiopaedia.org, rID: 60156]] | |||
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==References== | ==References== | ||
Latest revision as of 20:39, 7 February 2020
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Familial amyloidosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Familial amyloidosis CT scan On the Web |
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American Roentgen Ray Society Images of Familial amyloidosis CT scan |
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Risk calculators and risk factors for Familial amyloidosis CT scan |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D., Sabawoon Mirwais, M.B.B.S, M.D.[2]
Overview
CT scan may be helpful in the diagnosis of familial amyloidosis. CT scan can be done to assess for amyloid deposition in particular organs. It can also be done to rule out other causes of organ dysfunction. Findings on liver CT scan suggestive of familial amyloidosis include liver enlargement with heterogeneous decreased attenuation, asymmetric and triangular hepatomegaly with the apex at the falciform ligament, and parenchymal calcification. Findings on renal CT scan suggestive of familial amyloidosis include kidney enlargement with heterogeneous decreased attenuation, and parenchymal calcification. Findings on cardiac CT scan suggestive of familial amyloidosis include heart enlargement with heterogeneous decreased attenuation, cardiac calcification, and pericardial effusion.
CT scan
In hepatic amyloidosis, CT scan findings may include:
- Liver enlargement with heterogeneous decreased attenuation
- Asymmetric and triangular hepatomegaly with the apex at the falciform ligament (due to mild atrophic change of the lateral border of both hepatic lobes)
- Parenchymal calcification (rare)
In renal amyloidosis, CT scan findings may include:
- Kidney enlargement with heterogeneous decreased attenuation
- Parenchymal calcification (rare)
In cardiac amyloidosis, CT scan findings may include[1]:
- Heart enlargement with heterogeneous decreased attenuation
- Cardiac calcifications
- Pericardial effusion (rare)
Images
References
- ↑ Falk RH, Quarta CC, Dorbala S (2014). "How to image cardiac amyloidosis". Circ Cardiovasc Imaging. 7 (3): 552–62. doi:10.1161/CIRCIMAGING.113.001396. PMC 4118308. PMID 24847009.