Molluscum contagiosum laboratory findings: Difference between revisions

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== Overview ==
== Overview ==
The diagnosis of MC is typically made by its clinical presentation and can be confirmed by histological demonstration of the cytoplasmic eosinophilic inclusions or molluscum bodies that are characteristic of poxvirus replication. <nowiki>''''Braunwald E, Kasper I, Petersdorf R. Harrison'</nowiki>s Principles of Internal Medicine. Acta Endocrinol (Bucharest) 19871499.
There are no diagnostic lab findings associated with molluscum contagiosum. The diagnosis of molluscum contagiosum should be made clinically. For confirmation of the diagnosis, pathological studies can be done which involve [[H&E stain|H&E staining]] of the infected tissue<ref name="pmid19871499">{{cite journal |vauthors=Pearce L, Brown WH |title=HEREDITARY ACHONDROPLASIA IN THE RABBIT : II. PATHOLOGIC ASPECTS |journal=J. Exp. Med. |volume=82 |issue=4 |pages=261–80 |year=1945 |pmid=19871499 |pmc=2135556 |doi= |url=}}</ref> and direct visualization. it is also recommended to test for other [[Sexually transmitted disease|sexually transmitted diseases]] in adults and for [[immunodeficiency]] related diseases.  
 
==Overview==
*The overview section should include the disease name in the first sentence.
*The goal is to summarize the laboratory findings page in several sentences. This section can be the same as the laboratory findings segment on the overview page.
*To see an example of an overview section on a laboratory findings page, click [[Osteoporosis laboratory findings#Overview|here]].
===Template===
*'''First Sentence:'''
:An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name]
:OR
:Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
:OR
:There are no diagnostic lab findings associated with [disease name].
 
*'''Additional Sentences:'''
:Additional Sentence 1: [Test] is usually normal among patients with [disease name].
:Additional Sentence 2: Some patients with [disease name] may have elevated/reduced concentrations of [test], which is usually suggestive of [progression/complication].


==Laboratory Findings==
==Laboratory Findings==
*Outline or list the pertintent laboratory tests that you should obtain for the disease you are describing.
* Laboratory studies usually are not indicated in children with molluscum contagiosum. Sexually active adolescents and adults with genital lesions should be evaluated for the presence of other [[Sexually transmitted disease|sexually transmitted diseases]].  
*Make sure you also indicate what the laborotory finding would be.
* Patients with extensive lesions should be tested for [[Human Immunodeficiency Virus|human immunodeficiency virus (HIV) infection]], and the possibility of other immune system disorders should also be considered.  
*For an example of a laboratory findings section on a laboratory findings page, click [[Osteoporosis#Laboratory Findings|here]].
* [[Electron microscopy|Electron microscopic]] evaluation of tissue is not a part of routine diagnosis procedure, but if done it may show:
*You can include subheadings to describe special types of laboratory tests.
**Typical brick-shaped [[poxvirus]] particles inside the infected tissue which is highly specific for diagnosis.
* Laboratory studies usually are not indicated in children with molluscum contagiosum. Sexually active adolescents and adults with genital lesions should be evaluated for the presence of other sexually transmitted diseases. Patients with extensive lesions should be tested for human immunodeficiency virus (HIV) infection, and the possibility of other immune system disorders should also be considered.  
**[[Electron microscopy]] can also identify infected cells that appear normal on light microscopy


==References==
==References==
{{reflist|2}}
{{reflist|2}}
[[Category:Emergency mdicine]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Dermatology]]
[[Category:Otolaryngology]]

Latest revision as of 22:45, 29 July 2020

Molluscum contagiosum Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Molluscum contagiosum from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic criteria

History and Symptoms

Physical Examination

Laboratory Findings

X ray

Ultrasound

CT Scan

MRI

Other Imaging Studies

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]

Overview

There are no diagnostic lab findings associated with molluscum contagiosum. The diagnosis of molluscum contagiosum should be made clinically. For confirmation of the diagnosis, pathological studies can be done which involve H&E staining of the infected tissue[1] and direct visualization. it is also recommended to test for other sexually transmitted diseases in adults and for immunodeficiency related diseases.

Laboratory Findings

  • Laboratory studies usually are not indicated in children with molluscum contagiosum. Sexually active adolescents and adults with genital lesions should be evaluated for the presence of other sexually transmitted diseases.
  • Patients with extensive lesions should be tested for human immunodeficiency virus (HIV) infection, and the possibility of other immune system disorders should also be considered.
  • Electron microscopic evaluation of tissue is not a part of routine diagnosis procedure, but if done it may show:
    • Typical brick-shaped poxvirus particles inside the infected tissue which is highly specific for diagnosis.
    • Electron microscopy can also identify infected cells that appear normal on light microscopy

References

  1. Pearce L, Brown WH (1945). "HEREDITARY ACHONDROPLASIA IN THE RABBIT : II. PATHOLOGIC ASPECTS". J. Exp. Med. 82 (4): 261–80. PMC 2135556. PMID 19871499.