Molluscum contagiosum historical perspective: Difference between revisions

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{{Molluscum contagiosum}}
{{Molluscum contagiosum}}
{{CMG}};{{AE}}{{MIR}}
{{CMG}}; {{AE}} {{MIR}}
== Overview ==
== Overview ==
Molluscum contagiosum was first discovered by Bateman in 1817 in his second edition of his synopsis. In 1841 Paterson demonstrated molluscum contagiosum infectious nature.The viral nature of the disease demonstrated by Juliusberg in 1905. Outbreaks have occurred in the different settings like swimming pools, but the exact information about outbreaks is not available due report policy.
Molluscum contagiosum was first described by Bateman in 1817 in the second edition of his synopsis. In 1841, Paterson demonstrated molluscum contagiosum's infectious nature. The viral nature of the disease was demonstrated by Juliusberg in 1905.
==Discovery==
 
== Historical Perspective ==
 
===Discovery===
Molluscum contagiosum was first discovered by Bateman in 1817.<ref name="pmid4336666">{{cite journal |vauthors=Pickering WR, Woods RA |title=The uptake and incorporation of purines by wild-type Saccharomyces cerevisiae and a mutant resistant to 4-aminopyrazolo (3,4-d) pyrimidine |journal=Biochim. Biophys. Acta |volume=264 |issue=1 |pages=45–58 |year=1972 |pmid=4336666 |doi= |url=}}</ref>
Molluscum contagiosum was first discovered by Bateman in 1817.<ref name="pmid4336666">{{cite journal |vauthors=Pickering WR, Woods RA |title=The uptake and incorporation of purines by wild-type Saccharomyces cerevisiae and a mutant resistant to 4-aminopyrazolo (3,4-d) pyrimidine |journal=Biochim. Biophys. Acta |volume=264 |issue=1 |pages=45–58 |year=1972 |pmid=4336666 |doi= |url=}}</ref>


==Landmark Events in the Development of Treatment Strategies==
===Landmark Events in the Development of Treatment Strategies===
* Molluscum contagiosum was first discovered by Bateman in 1817 in his second edition of his synopsis.<ref name="pmid4336666" />
* Molluscum contagiosum was first discovered by Bateman in 1817 in his second edition of his synopsis.<ref name="pmid4336666" />
* In 1841 Paterson demonstrated molluscum contagiosum infectious nature.
* In 1841, Paterson demonstrated molluscum contagiosum infectious nature.
* The molluscum or Henderson-Paterson bodies (intracytoplasmic inclusion bodies, lobules containing hyalinized molluscum bodies) were also described by Henderson and Paterson in 1841.<ref name="pmid3524303">{{cite journal |vauthors=Torres A |title=The molluscum body. The Henderson-Paterson body with Lipschütz granules |journal=Am J Dermatopathol |volume=8 |issue=3 |pages=260–2 |year=1986 |pmid=3524303 |doi= |url=}}</ref>
* Also in 1841, Henderson-Paterson bodies (intracytoplasmic [[inclusion bodies]], lobules containing hyalinized molluscum bodies) were described by scientists Henderson and Paterson.<ref name="pmid3524303">{{cite journal |vauthors=Torres A |title=The molluscum body. The Henderson-Paterson body with Lipschütz granules |journal=Am J Dermatopathol |volume=8 |issue=3 |pages=260–2 |year=1986 |pmid=3524303 |doi= |url=}}</ref>
* The viral nature of the disease demonstrated by Juliusberg in 1905.<ref name="pmid15437050">{{cite journal |vauthors=RAKE G, BLANK H |title=The relationship of host and virus in molluscum contagiosum |journal=J. Invest. Dermatol. |volume=15 |issue=2 |pages=81–93 |year=1950 |pmid=15437050 |doi= |url=}}</ref>
* In 1905, the viral nature of the disease was demonstrated by Juliusberg.<ref name="pmid15437050">{{cite journal |vauthors=RAKE G, BLANK H |title=The relationship of host and virus in molluscum contagiosum |journal=J. Invest. Dermatol. |volume=15 |issue=2 |pages=81–93 |year=1950 |pmid=15437050 |doi= |url=}}</ref>
* Molluscum contagiosum virus types I-IV were identified with the advance of the technology through restrictive endonuclease analysis of the genomes of isolates.<ref name="urlwww.microbiologyresearch.org">{{cite web |url=http://www.microbiologyresearch.org/docserver/fulltext/jgv/65/5/JV0650050875.pdf?expires=1496763006&id=id&accname=guest&checksum=3F95D045A98BEE2DC076E265C060AC3E |title=www.microbiologyresearch.org |format= |work= |accessdate=}}</ref>
* In 1997, Senkevich et al were the first who described [[molluscum contagiosum virus]] (MCV) genome.<ref name="pmid9201214">{{cite journal |vauthors=Senkevich TG, Koonin EV, Bugert JJ, Darai G, Moss B |title=The genome of molluscum contagiosum virus: analysis and comparison with other poxviruses |journal=Virology |volume=233 |issue=1 |pages=19–42 |year=1997 |pmid=9201214 |doi=10.1006/viro.1997.8607 |url=}}</ref>
 
* Molluscum contagiosum virus types I-IV were identified with the advance of the technology through restrictive [[Endonucleases|endonuclease]] analysis of the [[Genome|genomes]] of isolates.<ref name="urlwww.microbiologyresearch.org">{{cite web |url=http://www.microbiologyresearch.org/docserver/fulltext/jgv/65/5/JV0650050875.pdf?expires=1496763006&id=id&accname=guest&checksum=3F95D045A98BEE2DC076E265C060AC3E |title=www.microbiologyresearch.org |format= |work= |accessdate=}}</ref>
==Impact on Cultural History==
* An outbreak of Molluscum contagiosum has been reported in a small rural community. The outbreak infected 34 patients, most of them were children between 9-18 years old. Rsearchers reported the spread as a result of direct contact and by fomites.<ref name="pmid1889869">{{cite journal |vauthors=Oren B, Wende SO |title=An outbreak of molluscum contagiosum in a kibbutz |journal=Infection |volume=19 |issue=3 |pages=159–61 |year=1991 |pmid=1889869 |doi= |url=}}</ref>
 
* Outbreaks have occurred in the following settings:
** Swimming pools (in children)
** Wrestling matches
** During surgery, by a surgeon with a hand lesion
** Via tattoos (although rarely)
** Sexually: MC can be sexually transmitted but not all genital lesions are sexually transmitted.<ref name="urlMolluscum Contagiosum - Oklahoma State Department of Health">{{cite web |url=https://www.ok.gov/health/Disease,_Prevention,_Preparedness/Acute_Disease_Service/Disease_Information/Molluscum_Contagiosum.html |title=Molluscum Contagiosum - Oklahoma State Department of Health |format= |work= |accessdate=}}</ref>


==References==
==References==
{{reflist|2}}
{{reflist|2}}
[[Category:Emergency mdicine]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Dermatology]]
[[Category:Otolaryngology]]

Latest revision as of 22:45, 29 July 2020

Molluscum contagiosum Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Molluscum contagiosum from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic criteria

History and Symptoms

Physical Examination

Laboratory Findings

X ray

Ultrasound

CT Scan

MRI

Other Imaging Studies

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]

Overview

Molluscum contagiosum was first described by Bateman in 1817 in the second edition of his synopsis. In 1841, Paterson demonstrated molluscum contagiosum's infectious nature. The viral nature of the disease was demonstrated by Juliusberg in 1905.

Historical Perspective

Discovery

Molluscum contagiosum was first discovered by Bateman in 1817.[1]

Landmark Events in the Development of Treatment Strategies

  • Molluscum contagiosum was first discovered by Bateman in 1817 in his second edition of his synopsis.[1]
  • In 1841, Paterson demonstrated molluscum contagiosum infectious nature.
  • Also in 1841, Henderson-Paterson bodies (intracytoplasmic inclusion bodies, lobules containing hyalinized molluscum bodies) were described by scientists Henderson and Paterson.[2]
  • In 1905, the viral nature of the disease was demonstrated by Juliusberg.[3]
  • In 1997, Senkevich et al were the first who described molluscum contagiosum virus (MCV) genome.[4]
  • Molluscum contagiosum virus types I-IV were identified with the advance of the technology through restrictive endonuclease analysis of the genomes of isolates.[5]

References

  1. ↑ 1.0 1.1 Pickering WR, Woods RA (1972). "The uptake and incorporation of purines by wild-type Saccharomyces cerevisiae and a mutant resistant to 4-aminopyrazolo (3,4-d) pyrimidine". Biochim. Biophys. Acta. 264 (1): 45–58. PMID 4336666.
  2. ↑ Torres A (1986). "The molluscum body. The Henderson-Paterson body with Lipschütz granules". Am J Dermatopathol. 8 (3): 260–2. PMID 3524303.
  3. ↑ RAKE G, BLANK H (1950). "The relationship of host and virus in molluscum contagiosum". J. Invest. Dermatol. 15 (2): 81–93. PMID 15437050.
  4. ↑ Senkevich TG, Koonin EV, Bugert JJ, Darai G, Moss B (1997). "The genome of molluscum contagiosum virus: analysis and comparison with other poxviruses". Virology. 233 (1): 19–42. doi:10.1006/viro.1997.8607. PMID 9201214.
  5. ↑ "www.microbiologyresearch.org" (PDF).
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