Medical therapy template

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Charmaine Patel, M.D. [2]

Introduction to the Medical Therapy Page

• The page name should be "(Disease name) medical therapy", with only the first letter of the title capitalized.
• Goal: To provide a comprehensive description of the main medical therapies used in the treatment of the disease you are describing.
• As with all microchapter pages linking to the main page, at the top of the edit box put {{CMG}}, your name template, and the microchapter navigation template you created at the beginning.
• Remember to create links within Wikidoc by placing [[square brackets]] around key words which you want to link to other pages. Make sure you makes your links as specific as possible. For example if a sentence contained the phrase anterior spinal artery syndrome, the link should be to anterior spinal artery syndrome not anterior or artery or syndrome. For more information on how to create links click here.
• Remember to follow the same format and capitalization of letters as outlined in the template below.
• You should include the name of the disease in the first sentence of every subsection.

Overview

• The overview section should include the disease name in the first sentence.
• The goal is to summarize the medical therapies used in the treating the disease in few sentences.
• To see an example of an overview section on a medical therapy page, click here.
• The sentence should be based on the strength of the recommendation and level of evidence (see Table from ACC/AHA Guidelines)

Template

• First Sentences:

[Disease name] is a medical emergency.

AND/OR

The mainstay of therapy for [disease name] is [therapy].

OR

The predominant therapy for [malignancy] is surgical resection. Adjunctive chemotherapy and radiation may be required.

OR

The optimal therapy for [malignancy] depends on the stage at diagnosis.

• Examples:

Example 1: Acute bacterial meningitis is a medical emergency.

Example 2: The mainstay of therapy for EBV mononucleosis is supportive care.

Example 3: The predominant therapy for acinic cell carcinoma is surgical resection. Adjunctive chemotherapy and radiation may be required.

Example 4: The optimal therapy for small cell carcinoma depends on the stage at diagnosis.

• Additional Sentences:

Additional Sentence 1: [Therapy] (is recommended/is useful/can be effective/might be reasonable- see Table 1) among all patients who develop [disease name].

Additional Sentence 2: Pharmacologic medical therapy (is recommended/is useful/can be effective/might be reasonable- see Table 1) among patients with [disease subclass 1], [disease subclass 2], and [disease subclass 3].

Additional Sentence 3: Pharmacologic medical therapies for [disease name] include (either) [therapy 1], [therapy 2], and/or [therapy 3].

Additional Sentence 4: Empiric therapy for [disease name] depends on [disease factor 1] and [disease factor 2].

Additional Sentence 6: Patients with [disease subclass 1] are treated with [therapy 1], whereas patients with [disease subclass 2] are treated with [therapy 2].

Additional Sentence 7: [Therapy] is the drug of choice to treat [disease name].

Additional Sentence 8: [Therapy] is the preferred drug for the treatment of [disease name].

Additional Sentence 9: Supportive therapy for [disease name] includes [therapy 1], [therapy 2], and [therapy 3].

Additional Sentence 10: Chemotherapy is indicated for [disease subclass 1] as adjuvant therapy and for [disease subclass 2] as first line therapy.

Additional Sentence 11: The majority of cases of [disease name] are self-limited and only require supportive care.

• Examples:

Example 1: Antimicrobial therapy (is recommended/is useful/can be effective/might be reasonable- see Table 1) among all patients who develop bacterial pneumonia.

Example 2: Antimicrobial therapy (is recommended/is useful/can be effective/might be reasonable- see Table 1) among all patients who develop septic arthritis.

Example 3: Antimicrobial therapy (is recommended/is useful/can be effective/might be reasonable- see Table 1) among patients with moderate and severe furuncles.

Example 4: Empiric antimicrobial therapies for furuncle include either TMP-SMX or Doxycycline for moderate furuncles, and either Vancomycin, Daptomycin, Linezolid, or Ceftaroline for severe furuncles.

Example 5: Empiric antimicrobial therapy for endocarditis depends on the nature of the valve (native vs. prosthetic) and the onset following valve implantation (less than 1 year vs. more than 1 year).

Example 6: Patients with gonococcal urethritis are treated with Azithromycin and either Ceftriaxone or Cefixime. Patients with non-gonococcal urethritis are treated with either Azithromycin or Doxycycline.

Example 7: Penicillin is the drug of choice to treat rheumatic fever.

Example 8: Penicillin G is the preferred drug for the treatment of all stages of syphilis.

Example 9: Supportive therapy for adenovirus upper respiratory infection includes bed rest, fluids, and anti-inflammatory drugs.

Example 10: Chemotherapy is indicated for high risk melanomas (stages IIB-IV) as adjuvant therapy and for metastatic disease as first-line therapy.

Example 11: The majority of cases of adenovirus upper respiratory tract infection are self-limited and only require supportive care.

Table from the ACC/AHA with recommended phrases based on class of recommendation and level of evidence.

Preferred Template Statements

IF there is no known treatment for the disease:

• There is no treatment for [disease name]; the mainstay of therapy is supportive care.
• Supportive therapy for [disease name] includes [therapy 1], [therapy 2], and [therapy 3].
• The majority of cases of [disease name] are self-limited and require only supportive care.

IF the disease constitutes a medical emergency: 

• [Disease name] is a medical emergency and requires prompt treatment.

IF there is a specific preferred modality of medical therapy:

• The mainstay of treatment for [disease name] is [therapy].

 

Additional Sentences

• The optimal therapy for [malignancy name] depends on the stage at diagnosis.
• [Therapy] (is recommended/is useful/can be effective/might be reasonable- see Table 1) among all patients who develop [disease name].
• Pharmacologic medical therapy (is recommended/is useful/can be effective/might be reasonable- see Table 1) among patients with [disease subclass 1], [disease subclass 2], and [disease subclass 3].
• Pharmacologic medical therapies for [disease name] include (either) [therapy 1], [therapy 2], and/or [therapy 3].
• Empiric therapy for [disease name] depends on [disease factor 1] and [disease factor 2].
• Patients with [disease subclass 1] are treated with [therapy 1], whereas patients with [disease subclass 2] are treated with [therapy 2].

• 1 Stage 1 - Name of stage
  • 1.1 Specific Organ system involved 1
    • 1.1.1 Adult
      • Preferred regimen (1): drug name 100 mg PO q12h for 10-21 days (Contraindications/specific instructions)
      • Preferred regimen (2): drug name 500 mg PO q8h for 14-21 days
      • Preferred regimen (3): drug name 500 mg q12h for 14-21 days
      • Alternative regimen (1): drug name 500 mg PO q6h for 7–10 days
      • Alternative regimen (2): drug name 500 mg PO q12h for 14–21 days
      • Alternative regimen (3): drug name 500 mg PO q6h for 14–21 days
    • 1.1.2 Pediatric
      • 1.1.2.1 (Specific population e.g. children < 8 years of age)
        • Preferred regimen (1): drug name 50 mg/kg PO per day q8h (maximum, 500 mg per dose)
        • Preferred regimen (2): drug name 30 mg/kg PO per day in 2 divided doses (maximum, 500 mg per dose)
        • Alternative regimen (1): drug name10 mg/kg PO q6h (maximum, 500 mg per day)
        • Alternative regimen (2): drug name 7.5 mg/kg PO q12h (maximum, 500 mg per dose)
        • Alternative regimen (3): drug name 12.5 mg/kg PO q6h (maximum, 500 mg per dose)
      • 1.1.2.2 (Specific population e.g. 'children < 8 years of age')
        • Preferred regimen (1): drug name 4 mg/kg/day PO q12h（maximum, 100 mg per dose）
        • Alternative regimen (1): drug name 10 mg/kg PO q6h (maximum, 500 mg per day)
        • Alternative regimen (2): drug name 7.5 mg/kg PO q12h (maximum, 500 mg per dose)
        • Alternative regimen (3): drug name 12.5 mg/kg PO q6h (maximum, 500 mg per dose)
  • 2.1 Specific Organ system involved 2
    • 2.1.1 Adult
      • Preferred regimen (1): drug name 500 mg PO q8h
    • 2.1.2 Pediatric
      • Preferred regimen (1): drug name 50 mg/kg/day PO q8h (maximum, 500 mg per dose)

Medical Therapy

• Describe the key medical therapies used the treat the disease, and their main mode of action.
• You may want to include sub-sections for each therapy used.
• To search for guidelines, go to the National Guideline Clearinghouse (http://www.guidelines.gov/).
• For an example of the medical therapy segment in a medical therapy page, click here.

References

• References should be cited for the material that you have put on your page. Type in {{reflist|2}}.This will generate your references in small font, in two columns, with links to the original article and abstract.
• For information on how to add references into your page, click here.

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