Thiamylal: Difference between revisions
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| IUPAC_name = 5-allyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1''H'',5''H'')-dione | | IUPAC_name = 5-allyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1''H'',5''H'')-dione | ||
| image = ThiamylalSVG. | | image = ThiamylalSVG.png | ||
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[[Category:Thiobarbiturates]] | [[Category:Thiobarbiturates]] | ||
[[Category:Drug]] | [[Category:Drug]] | ||
Latest revision as of 20:32, 10 April 2015
Clinical data | |
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Synonyms | Thiamylal, Thioseconal, Surital |
AHFS/Drugs.com | International Drug Names |
ATCvet code | |
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Pharmacokinetic data | |
Metabolism | Hepatic |
Elimination half-life | 14.3 h (cats) |
Identifiers | |
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CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C12H18N2O2S |
Molar mass | 254.35 g/mol |
3D model (JSmol) | |
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WikiDoc Resources for Thiamylal |
Articles |
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Most recent articles on Thiamylal |
Media |
Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Thiamylal at Clinical Trials.gov Clinical Trials on Thiamylal at Google
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Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Thiamylal
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Books |
News |
Commentary |
Definitions |
Patient Resources / Community |
Patient resources on Thiamylal Discussion groups on Thiamylal Directions to Hospitals Treating Thiamylal Risk calculators and risk factors for Thiamylal
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Healthcare Provider Resources |
Causes & Risk Factors for Thiamylal |
Continuing Medical Education (CME) |
International |
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Business |
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Thiamylal (Surital) is a barbiturate derivative invented in the 1950s. It has sedative, anticonvulsant, and hypnotic effects, and is used as a strong but short acting sedative. Thiamylal is still in current use, primarily for induction in surgical anaesthesia [1] or as an anticonvulsant to counteract side effects from other anaesthetics.[2] It is the thiobarbiturate analogue of secobarbital.
References
- ↑ Hsieh MY, Hung GY, Hsieh YL, Chang CY, Hwang B. Deep sedation with methohexital or thiamylal with midazolam for invasive procedures in children with acute lymphoblastic leukemia. Acta Paediatrica Taiwan. 2005 Sep-Oct;46(5):294-300.
- ↑ Tsai CJ, Wang HM, Lu IC, Tai CF, Wang LF, Soo LY, Lu DV. Seizure after local anesthesia for nasopharyngeal angiofibroma. Kaohsiung Journal of Medical Sciences. 2007 Feb;23(2):97-100.