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| __NOTOC__
| | #REDIRECT [[Clopidogrel#Overdosage]] |
| {{Clopidogrel}}
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| {{CMG}}; {{AE}} {{JH}}
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| ==Overdosage==
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| Platelet inhibition by Plavix is irreversible and will last for the life of the [[platelet]]. Overdose following clopidogrel administration may result in bleeding complications. A single oral dose of clopidogrel at 1500 or 2000 mg/kg was lethal to mice and to rats and at 3000 mg/kg to baboons. Symptoms of acute toxicity were [[vomiting]], [[prostration]], difficult breathing, and gastrointestinal hemorrhage in animals.
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| Based on biological plausibility, platelet transfusion may restore clotting ability.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = PLAVIX (CLOPIDOGREL BISULFATE) TABLET, FILM COATED [BRISTOL-MYERS SQUIBB/SANOFI PHARMACEUTICALS PARTNERSHIP] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=01b14603-8f29-4fa3-8d7e-9d523f802e0b | publisher = | date = | accessdate = }}</ref>
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| ==References==
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| {{Reflist}}
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| {{FDA}}
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| [[Category:Cardiovascular Drugs]]
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| [[Category:Drugs]]
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