Hydralazine injection dosage and administration: Difference between revisions

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__NOTOC__
#REDIRECT [[Hydralazine#Adult Indications and Dosage]]
{{Hydralazine}}
{{CMG}}; {{AE}} {{AK}}
 
==DOSAGE AND ADMINISTRATION==
 
When there is urgent need, therapy in the hospitalized patient may be initiated intramuscularly or as a rapid intravenous bolus injection directly into the vein.  Hydralazine Hydrochloride Injection should be used only when the drug cannot be given orally.  The usual dose is 20 to 40 mg, repeated as necessary.
 
Certain patients (especially those with marked renal damage) may require a lower dose.  Blood pressure should be checked frequently.  It may begin to fall within a few minutes after injection, with the average maximal decrease occurring in 10 to 80 minutes.  In cases where there has been increased [[intracranial pressure]], lowering the blood pressure may increase [[cerebral ischemia]].  Most patients can be transferred to oral hydralazine hydrochloride within 24 to 48 hours.
 
The product should be used immediately after the vial is opened.  The product should not be added to infusion solutions.  Hydralazine Hydrochloride Injection may discolor upon contact with metal; discolored solutions should be discarded.
 
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = HYDRALAZINE HYDROCHLORIDE INJECTION [FRESENIUS KABI USA, LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c3797028-c625-4f70-ae69-8a5f6f23f1b8 | publisher =  | date =  | accessdate = 10 March 2014 }}</ref>
 
==References==
 
{{Reflist|2}}
 
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]

Latest revision as of 22:10, 21 July 2014