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| {{Atrial septal defect}}
| | #REDIRECT [[Atrial septal defect risk factors]] |
| {{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [[mailto:psingh@perfuse.org]]; {{CZ}}; '''Assistant Editor(s)-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [[mailto:kfeeney@perfuse.org]]
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| ==Overview==
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| As is common with most congenital heart conditions, the exact cause of atrial septal defect is not known. Research suggests a potential link between genetic conditions such as [[Down syndrome]] and the development of an atrial septal defect. Other potential causes include exposure to environmental contaminants such as [[rubella]] as well as [[alcohol]] consumption.
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| ==Causes==
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| The cause of atrial septal defect is not known. There does appear to be a genetic component to the disease as it often occurs in patients with [[Down syndrome]]. As a parent, if you or a sibling of a child have a [[congenital heart defect]], then you should consider [[genetic counseling]].
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| If the mother contracts [[rubella]] (german measles) during pregnancy, this can increase the risk of [[congenital heart disease]]. In one study, exposure to [[alcohol]] during pregnancy doubled the risk of an [[atrial septal defect]]<ref name="pmid1397217">{{cite journal| author=Tikkanen J, Heinonen OP| title=Risk factors for atrial septal defect. | journal=Eur J Epidemiol | year= 1992 | volume= 8 | issue= 4 | pages= 509-15 | pmid=1397217 | doi= | pmc= | url= }} </ref>. More details about the genetics and embryology of atrial septal defects can be found in the microchapters below:
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| ===[[Atrial septal defect genetics|Genetics]]===
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| ===[[Atrial septal defect embryology|Embryology]]===
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| ==References==
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| {{reflist|2}}
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| [[Category:Cardiology]]
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| [[Category:Congenital heart disease]]
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| [[Category:Pediatrics]]
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| [[Category:Mature chapter]]
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| {{WH}}
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| {{WS}}
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