Fractional excretion of uric acid: Difference between revisions
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The normal values are: | The normal values are: | ||
* 6 to 12%<ref name="pmid1200033">{{cite journal| author=Berger L, Yü TF| title=Renal function in gout. IV. An analysis of 524 gouty subjects including long-term follow-up studies. | journal=Am J Med | year= 1975 | volume= 59 | issue= 5 | pages= 605-13 | pmid=1200033 | doi=10.1016/0002-9343(75)90222-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1200033 }} </ref> | * 6 to 12%<ref name="pmid1200033">{{cite journal| author=Berger L, Yü TF| title=Renal function in gout. IV. An analysis of 524 gouty subjects including long-term follow-up studies. | journal=Am J Med | year= 1975 | volume= 59 | issue= 5 | pages= 605-13 | pmid=1200033 | doi=10.1016/0002-9343(75)90222-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1200033 }} </ref> | ||
* 4 to 11%<ref name="pmid30560127">{{cite journal| author=Maesaka JK, Imbriano LJ, Miyawaki N| title=Determining Fractional Urate Excretion Rates in Hyponatremic Conditions and Improved Methods to Distinguish Cerebral/Renal Salt Wasting From the Syndrome of Inappropriate Secretion of Antidiuretic Hormone. | journal=Front Med (Lausanne) | year= 2018 | volume= 5 | issue= | pages= 319 | pmid=30560127 | doi=10.3389/fmed.2018.00319 | pmc=6284366 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30560127 }} </ref> | |||
A value of 4% for less suggests prerenal causes of hyponatremia<ref name="pmid30560127">{{cite journal| author=Maesaka JK, Imbriano LJ, Miyawaki N| title=Determining Fractional Urate Excretion Rates in Hyponatremic Conditions and Improved Methods to Distinguish Cerebral/Renal Salt Wasting From the Syndrome of Inappropriate Secretion of Antidiuretic Hormone. | journal=Front Med (Lausanne) | year= 2018 | volume= 5 | issue= | pages= 319 | pmid=30560127 | doi=10.3389/fmed.2018.00319 | pmc=6284366 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30560127 }} </ref>. | == Diagnosis of causes of hyponatremia == | ||
In the diagnosis of [[hyponatremia]]: | |||
* A value of 4% for less suggests prerenal causes<ref name="pmid30560127">{{cite journal| author=Maesaka JK, Imbriano LJ, Miyawaki N| title=Determining Fractional Urate Excretion Rates in Hyponatremic Conditions and Improved Methods to Distinguish Cerebral/Renal Salt Wasting From the Syndrome of Inappropriate Secretion of Antidiuretic Hormone. | journal=Front Med (Lausanne) | year= 2018 | volume= 5 | issue= | pages= 319 | pmid=30560127 | doi=10.3389/fmed.2018.00319 | pmc=6284366 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30560127 }} </ref>. | |||
* A normal value (4 to 11%) suggests [[psychogenic polydipsia]] or [[reset osmostat]]<ref name="pmid30560127">{{cite journal| author=Maesaka JK, Imbriano LJ, Miyawaki N| title=Determining Fractional Urate Excretion Rates in Hyponatremic Conditions and Improved Methods to Distinguish Cerebral/Renal Salt Wasting From the Syndrome of Inappropriate Secretion of Antidiuretic Hormone. | journal=Front Med (Lausanne) | year= 2018 | volume= 5 | issue= | pages= 319 | pmid=30560127 | doi=10.3389/fmed.2018.00319 | pmc=6284366 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30560127 }} </ref>. | |||
* If the FEUA is high (higher than 11%), this suggests [[SIADH]], [[thiazide#Thiazide-induced hyponatremia|thiazide-induced hyponatremia]], or [[renal salt wasting]]<ref name="pmid30560127">{{cite journal| author=Maesaka JK, Imbriano LJ, Miyawaki N| title=Determining Fractional Urate Excretion Rates in Hyponatremic Conditions and Improved Methods to Distinguish Cerebral/Renal Salt Wasting From the Syndrome of Inappropriate Secretion of Antidiuretic Hormone. | journal=Front Med (Lausanne) | year= 2018 | volume= 5 | issue= | pages= 319 | pmid=30560127 | doi=10.3389/fmed.2018.00319 | pmc=6284366 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30560127 }} </ref>. | |||
==See also== | ==See also== | ||
Latest revision as of 18:46, 2 July 2022
In water-electrolyte imbalance, Fractional excretion of uric acid (FEUA) is defined as fraction of uric acid filtered by the kidneys that is then excreted by the kidneys.
The normal values are:
Diagnosis of causes of hyponatremia
In the diagnosis of hyponatremia:
- A value of 4% for less suggests prerenal causes[2].
- A normal value (4 to 11%) suggests psychogenic polydipsia or reset osmostat[2].
- If the FEUA is high (higher than 11%), this suggests SIADH, thiazide-induced hyponatremia, or renal salt wasting[2].
See also
External links
References
- ↑ Berger L, Yü TF (1975). "Renal function in gout. IV. An analysis of 524 gouty subjects including long-term follow-up studies". Am J Med. 59 (5): 605–13. doi:10.1016/0002-9343(75)90222-3. PMID 1200033.
- ↑ 2.0 2.1 2.2 2.3 Maesaka JK, Imbriano LJ, Miyawaki N (2018). "Determining Fractional Urate Excretion Rates in Hyponatremic Conditions and Improved Methods to Distinguish Cerebral/Renal Salt Wasting From the Syndrome of Inappropriate Secretion of Antidiuretic Hormone". Front Med (Lausanne). 5: 319. doi:10.3389/fmed.2018.00319. PMC 6284366. PMID 30560127.