PCDH1: Difference between revisions

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'''Protocadherin-1''' is a [[protein]] that in humans is encoded by the ''PCDH1'' [[gene]].<ref name="pmid8508762">{{cite journal |vauthors=Sano K, Tanihara H, Heimark RL, Obata S, Davidson M, St John T, Taketani S, Suzuki S | title = Protocadherins: a large family of cadherin-related molecules in central nervous system | journal = EMBO J | volume = 12 | issue = 6 | pages = 2249–56 |date=Jul 1993 | pmid = 8508762 | pmc = 413453 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PCDH1 protocadherin 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5097| accessdate = }}</ref>
'''Protocadherin-1''' is a [[protein]] that in humans is encoded by the ''PCDH1'' [[gene]].<ref name="pmid8508762">{{cite journal |vauthors=Sano K, Tanihara H, Heimark RL, Obata S, Davidson M, St John T, Taketani S, Suzuki S | title = Protocadherins: a large family of cadherin-related molecules in central nervous system | journal = EMBO J | volume = 12 | issue = 6 | pages = 2249–56 |date=Jul 1993 | pmid = 8508762 | pmc = 413453 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PCDH1 protocadherin 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5097| accessdate = }}</ref>
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{{PBB_Summary
{{PBB_Summary
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| summary_text = This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracellular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.<ref name="entrez" />
| summary_text = This gene belongs to the [[protocadherin]] subfamily within the [[cadherin]] superfamily. The encoded protein is a [[membrane protein]] found at cell-cell boundaries. It is involved in [[neural cell]] adhesion, suggesting a possible role in neuronal development. The protein includes an extracellular region, containing 7 cadherin-like domains, a transmembrane region and a [[C-terminal]] cytoplasmic region. Cells expressing the protein showed cell aggregation activity. [[Alternative splicing]] occurs in this gene.<ref name="entrez" />
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Latest revision as of 15:31, 14 February 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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Wikidata
View/Edit Human

Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene.[1][2]

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracellular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.[2]

References

  1. ↑ Sano K, Tanihara H, Heimark RL, Obata S, Davidson M, St John T, Taketani S, Suzuki S (Jul 1993). "Protocadherins: a large family of cadherin-related molecules in central nervous system". EMBO J. 12 (6): 2249–56. PMC 413453. PMID 8508762.
  2. ↑ 2.0 2.1 "Entrez Gene: PCDH1 protocadherin 1".

Further reading



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