Gallbladder cancer palliative treatment: Difference between revisions

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{{Gallbladder cancer}}
{{Gallbladder cancer}}
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* {{CMG}}; {{AE}}{{VKG}}


==Overview==
==Overview==
Palliative therapy in gallbladder cancer involves percutaneous transhepatic radiologic catheter bypass or endoscopically placed stents, standard external-beam radiation therapy, palliative surgery or standard chemotherapy.
[[Palliative therapy]] in [[gallbladder cancer]] involves [[percutaneous]] transhepatic radiologic catheter bypass or endoscopically placed [[stents]], standard external-beam [[radiation therapy]], palliative surgery or standard [[chemotherapy]].
 
==Palliative Treatment==
==Palliative Treatment==


Palliative treatment options may include the following:
[[Palliative treatment]] options may include the following:


*The preferred approach to biliary obstruction is '''percutaneous transhepatic radiologic catheter bypass''' or '''endoscopically placed stents'''<ref>Baron TH: Expandable metal stents for the treatment of cancerous obstruction of the gastrointestinal tract. N Engl J Med 344 (22): 1681-7, 2001.</ref>
'''Percutaneous transhepatic radiologic catheter bypass'''
*'''Standard external-beam radiation therapy''' can, on occasion, alleviate biliary obstruction in some patients and may supplement bypass procedures
 
*'''Palliative surgery''' may relieve bile duct obstruction and is warranted when symptoms produced by biliary blockade (pruritus, hepatic dysfunction, and cholangitis) outweigh other symptoms from the cancer
*The preferred approach to biliary obstruction is [[percutaneous]] transhepatic radiologic catheter bypass or endoscopically placed [[stents]].<ref name="pmid11386268">{{cite journal| author=Baron TH| title=Expandable metal stents for the treatment of cancerous obstruction of the gastrointestinal tract. | journal=N Engl J Med | year= 2001 | volume= 344 | issue= 22 | pages= 1681-7 | pmid=11386268 | doi=10.1056/NEJM200105313442206 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11386268  }} </ref>
*'''Standard chemotherapy''' is usually not effective, though occasional patients may be palliated<ref>Bartlett DL, Ramanathan RK, Deutsch M: Cancer of the biliary tree. In: DeVita VT Jr, Hellman S, Rosenberg SA, eds.: Cancer: Principles and Practice of Oncology. 7th ed. Philadelphia, Pa: Lippincott Williams & Wilkins, 2005, pp 1009-31.</ref> <ref>Hejna M, Pruckmayer M, Raderer M: The role of chemotherapy and radiation in the management of biliary cancer: a review of the literature. Eur J Cancer 34 (7): 977-86, 1998.</ref>
'''Standard external-beam radiation therapy'''
*Standard external-beam [[radiation therapy]] can, on occasion, alleviate [[biliary]] obstruction in some patients and may supplement bypass procedures.
'''Palliative surgery'''
*[[Palliative]] surgery may relieve bile duct obstruction and is warranted when symptoms produced by biliary blockade ([[pruritus]], [[hepatic dysfunction]], and [[cholangitis]]) outweigh other symptoms from the cancer.
'''Standard chemotherapy'''
*Standard [[chemotherapy]] is usually not effective, though occasional patients may be palliated.<ref name="pmid9849443">{{cite journal| author=Hejna M, Pruckmayer M, Raderer M| title=The role of chemotherapy and radiation in the management of biliary cancer: a review of the literature. | journal=Eur J Cancer | year= 1998 | volume= 34 | issue= 7 | pages= 977-86 | pmid=9849443 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9849443  }}</ref>


==References==
==References==
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Latest revision as of 15:37, 10 January 2019

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Overview

Palliative therapy in gallbladder cancer involves percutaneous transhepatic radiologic catheter bypass or endoscopically placed stents, standard external-beam radiation therapy, palliative surgery or standard chemotherapy.

Palliative Treatment

Palliative treatment options may include the following:

Percutaneous transhepatic radiologic catheter bypass

  • The preferred approach to biliary obstruction is percutaneous transhepatic radiologic catheter bypass or endoscopically placed stents.[1]

Standard external-beam radiation therapy

  • Standard external-beam radiation therapy can, on occasion, alleviate biliary obstruction in some patients and may supplement bypass procedures.

Palliative surgery

Standard chemotherapy

  • Standard chemotherapy is usually not effective, though occasional patients may be palliated.[2]

References

  1. Baron TH (2001). "Expandable metal stents for the treatment of cancerous obstruction of the gastrointestinal tract". N Engl J Med. 344 (22): 1681–7. doi:10.1056/NEJM200105313442206. PMID 11386268.
  2. Hejna M, Pruckmayer M, Raderer M (1998). "The role of chemotherapy and radiation in the management of biliary cancer: a review of the literature". Eur J Cancer. 34 (7): 977–86. PMID 9849443.


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