Sinusoidal obstruction syndrome causes: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Sinusoidal obstruction syndrome}} | {{Sinusoidal obstruction syndrome}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{HS}} | ||
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==Overview== | ==Overview== | ||
The most common cause of sinusoidal obstruction syndrome is [[Hematopoietic stem cell transplantation|hematopoietic cell transplantation]]. Other less common causes include [[chemotherapeutic agents]] and [[Pyrrolizidine alkaloid|pyrrolizidine alkaloids]]. | |||
==Causes== | ==Causes== | ||
===Common causes=== | ===Common causes=== | ||
*Sinusoidal obstruction syndrome is most commonly caused by hematopoietic cell transplantation.<ref name="pmid8420443">{{cite journal |vauthors=McDonald GB, Hinds MS, Fisher LD, Schoch HG, Wolford JL, Banaji M, Hardin BJ, Shulman HM, Clift RA |title=Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients |journal=Ann. Intern. Med. |volume=118 |issue=4 |pages=255–67 |year=1993 |pmid=8420443 |doi= |url=}}</ref><ref name="pmid12744547">{{cite journal| author=Kumar S, DeLeve LD, Kamath PS, Tefferi A| title=Hepatic veno-occlusive disease (sinusoidal obstruction syndrome) after hematopoietic stem cell transplantation. | journal=Mayo Clin Proc | year= 2003 | volume= 78 | issue= 5 | pages= 589-98 | pmid=12744547 | doi=10.4065/78.5.589 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12744547 }} </ref> | *Sinusoidal obstruction syndrome is most commonly caused by [[Hematopoietic stem cell transplantation|hematopoietic cell transplantation]].<ref name="pmid8420443">{{cite journal |vauthors=McDonald GB, Hinds MS, Fisher LD, Schoch HG, Wolford JL, Banaji M, Hardin BJ, Shulman HM, Clift RA |title=Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients |journal=Ann. Intern. Med. |volume=118 |issue=4 |pages=255–67 |year=1993 |pmid=8420443 |doi= |url=}}</ref><ref name="pmid12744547">{{cite journal| author=Kumar S, DeLeve LD, Kamath PS, Tefferi A| title=Hepatic veno-occlusive disease (sinusoidal obstruction syndrome) after hematopoietic stem cell transplantation. | journal=Mayo Clin Proc | year= 2003 | volume= 78 | issue= 5 | pages= 589-98 | pmid=12744547 | doi=10.4065/78.5.589 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12744547 }} </ref> | ||
===Less common causes=== | ===Less common causes=== | ||
Other less common causes include: | Other less common causes include:<ref name="pmid27038846">{{cite journal| author=Valla DC, Cazals-Hatem D| title=Sinusoidal obstruction syndrome. | journal=Clin Res Hepatol Gastroenterol | year= 2016 | volume= 40 | issue= 4 | pages= 378-85 | pmid=27038846 | doi=10.1016/j.clinre.2016.01.006 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27038846 }} </ref> | ||
* | * [[Chemotherapeutic agents]] such as [[6-mercaptopurine|6-mercaptopurine,]] [[Thioguanine|6-thioguanine]], [[actinomycin D]], [[azathioprine]] or [[busulfan]] etc | ||
* [[Pyrrolidizine|Pyrrolizidine alkaloids]] | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Latest revision as of 15:33, 28 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Husnain Shaukat, M.D [2]
Overview
The most common cause of sinusoidal obstruction syndrome is hematopoietic cell transplantation. Other less common causes include chemotherapeutic agents and pyrrolizidine alkaloids.
Causes
Common causes
- Sinusoidal obstruction syndrome is most commonly caused by hematopoietic cell transplantation.[1][2]
Less common causes
Other less common causes include:[3]
- Chemotherapeutic agents such as 6-mercaptopurine, 6-thioguanine, actinomycin D, azathioprine or busulfan etc
- Pyrrolizidine alkaloids
References
- ↑ McDonald GB, Hinds MS, Fisher LD, Schoch HG, Wolford JL, Banaji M, Hardin BJ, Shulman HM, Clift RA (1993). "Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients". Ann. Intern. Med. 118 (4): 255–67. PMID 8420443.
- ↑ Kumar S, DeLeve LD, Kamath PS, Tefferi A (2003). "Hepatic veno-occlusive disease (sinusoidal obstruction syndrome) after hematopoietic stem cell transplantation". Mayo Clin Proc. 78 (5): 589–98. doi:10.4065/78.5.589. PMID 12744547.
- ↑ Valla DC, Cazals-Hatem D (2016). "Sinusoidal obstruction syndrome". Clin Res Hepatol Gastroenterol. 40 (4): 378–85. doi:10.1016/j.clinre.2016.01.006. PMID 27038846.