MORF4L2: Difference between revisions

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{{Underlinked|date=March 2014}}
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{{Infobox_gene}}
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'''Mortality factor 4-like protein 2''' is a [[protein]] that in humans is encoded by the ''MORF4L2'' [[gene]].<ref name="pmid9891081">{{cite journal |vauthors=Bertram MJ, Berube NG, Hang-Swanson X, Ran Q, Leung JK, Bryce S, Spurgers K, Bick RJ, Baldini A, Ning Y, Clark LJ, Parkinson EK, Barrett JC, Smith JR, Pereira-Smith OM | title = Identification of a Gene That Reverses the Immortal Phenotype of a Subset of Cells and Is a Member of a Novel Family of Transcription Factor-Like Genes | journal = Mol Cell Biol | volume = 19 | issue = 2 | pages = 1479–85 |date=Feb 1999 | pmid = 9891081 | pmc = 116076 | doi = 10.1128/mcb.19.2.1479}}</ref><ref name="pmid7584026">{{cite journal |vauthors=Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S | title = Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 | journal = DNA Res | volume = 1 | issue = 1 | pages = 27–35 |date=Dec 1995 | pmid = 7584026 | pmc =  | doi =10.1093/dnares/1.1.27 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MORF4L2 mortality factor 4 like 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9643| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Mortality factor 4 like 2
| HGNCid = 16849
| Symbol = MORF4L2
| AltSymbols =; KIAA0026; MORFL2; MRGX
| OMIM = 300409
| ECnumber = 
| Homologene = 22710
| MGIid = 1927167
| GeneAtlas_image1 = PBB_GE_MORF4L2_201994_at_tn.png
| Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005730 |text = nucleolus}}
| Process = {{GNF_GO|id=GO:0001558 |text = regulation of cell growth}} {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0016568 |text = chromatin modification}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9643
    | Hs_Ensembl = ENSG00000123562
    | Hs_RefseqProtein = NP_036418
    | Hs_RefseqmRNA = NM_012286
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = X
    | Hs_GenLoc_start = 102817080
    | Hs_GenLoc_end = 102829705
    | Hs_Uniprot = Q15014
    | Mm_EntrezGene = 56397
    | Mm_Ensembl = ENSMUSG00000031422
    | Mm_RefseqmRNA = XM_977957
    | Mm_RefseqProtein = XP_983051
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = X
    | Mm_GenLoc_start = 132079306
    | Mm_GenLoc_end = 132087973
    | Mm_Uniprot = Q3TME1
  }}
}}
'''Mortality factor 4 like 2''', also known as '''MORF4L2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: MORF4L2 mortality factor 4 like 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9643| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Nomura N, Miyajima N, Sazuka T, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. |journal=DNA Res. |volume=1 |issue= 1 |pages= 27-35 |year= 1995 |pmid= 7584026 |doi=  }}
*{{cite journal  | author=Nomura N |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement) |journal=DNA Res. |volume=1 |issue= 1 |pages= 47–56 |year= 1995 |pmid= 7584028 |doi=10.1093/dnares/1.1.47 |name-list-format=vanc| author2=Miyajima N | author3=Sazuka T | display-authors=3  | last4=Tanaka  | first4=A. | last5=Kawarabayasi  | first5=Y.  | last6=Sato  | first6=S. | last7=Nagase  | first7=T.  | last8=Seki  | first8=N.  | last9=Ishikawa  | first9=K.-i.  }}
*{{cite journal  | author=Nomura N, Miyajima N, Sazuka T, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). |journal=DNA Res. |volume=1 |issue= 1 |pages= 47-56 |year= 1995 |pmid= 7584028 |doi= }}
*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | author=Suzuki Y |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |name-list-format=vanc| author2=Yoshitomo-Nakagawa K | author3=Maruyama K | display-authors=3  | last4=Suyama  | first4=Akira  | last5=Sugano  | first5=Sumio  }}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  |vauthors=Hoja MR, Wahlestedt C, Höög C |title=A visual intracellular classification strategy for uncharacterized human proteins |journal=Exp. Cell Res. |volume=259 |issue= 1 |pages= 239–46 |year= 2000 |pmid= 10942595 |doi= 10.1006/excr.2000.4948 }}
*{{cite journal  | author=Bertram MJ, Bérubé NG, Hang-Swanson X, ''et al.'' |title=Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes. |journal=Mol. Cell. Biol. |volume=19 |issue= 2 |pages= 1479-85 |year= 1999 |pmid= 9891081 |doi= }}
*{{cite journal  | author=Sakai K |title=Interaction of a paraneoplastic cerebellar degeneration-associated neuronal protein with the nuclear helix-loop-helix leucine zipper protein MRG X |journal=Mol. Cell. Neurosci. |volume=19 |issue= 4 |pages= 477–84 |year= 2002 |pmid= 11988016 |doi= 10.1006/mcne.2001.1059 |name-list-format=vanc| author2=Shirakawa T | author3=Li Y | display-authors=3  | last4=Kitagawa  | first4=Y  | last5=Hirose  | first5=G }}
*{{cite journal  | author=Hoja MR, Wahlestedt C, Höög C |title=A visual intracellular classification strategy for uncharacterized human proteins. |journal=Exp. Cell Res. |volume=259 |issue= 1 |pages= 239-46 |year= 2000 |pmid= 10942595 |doi= 10.1006/excr.2000.4948 }}
*{{cite journal  |vauthors=Yochum GS, Ayer DE |title=Role for the Mortality Factors MORF4, MRGX, and MRG15 in Transcriptional Repression via Associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split |journal=Mol. Cell. Biol. |volume=22 |issue= 22 |pages= 7868–76 |year= 2002 |pmid= 12391155 |doi=10.1128/MCB.22.22.7868-7876.2002  | pmc=134742  }}
*{{cite journal | author=Sakai K, Shirakawa T, Li Y, ''et al.'' |title=Interaction of a paraneoplastic cerebellar degeneration-associated neuronal protein with the nuclear helix-loop-helix leucine zipper protein MRG X. |journal=Mol. Cell. Neurosci. |volume=19 |issue= 4 |pages= 477-84 |year= 2002 |pmid= 11988016 |doi= 10.1006/mcne.2001.1059 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Yochum GS, Ayer DE |title=Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split. |journal=Mol. Cell. Biol. |volume=22 |issue= 22 |pages= 7868-76 |year= 2002 |pmid= 12391155 |doi=  }}
*{{cite journal  | author=Cai Y |title=Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 42733–6 |year= 2003 |pmid= 12963728 |doi= 10.1074/jbc.C300389200  |name-list-format=vanc| author2=Jin J  | author3=Tomomori-Sato C  | display-authors=3  | last4=Sato  | first4=S  | last5=Sorokina  | first5=I  | last6=Parmely  | first6=TJ  | last7=Conaway  | first7=RC  | last8=Conaway  | first8=JW }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Tominaga K |title=MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner |journal=J. Biol. Chem. |volume=278 |issue= 49 |pages= 49618–24 |year= 2004 |pmid= 14506250 |doi= 10.1074/jbc.M309192200 |name-list-format=vanc| author2=Leung JK  | author3=Rookard P  | display-authors=3  | last4=Echigo  | first4=J  | last5=Smith  | first5=JR  | last6=Pereira-Smith  | first6=OM }}
*{{cite journal  | author=Cai Y, Jin J, Tomomori-Sato C, ''et al.'' |title=Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 42733-6 |year= 2003 |pmid= 12963728 |doi= 10.1074/jbc.C300389200 }}
*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285  |name-list-format=vanc| author2=Suzuki Y | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
*{{cite journal | author=Tominaga K, Leung JK, Rookard P, ''et al.'' |title=MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner. |journal=J. Biol. Chem. |volume=278 |issue= 49 |pages= 49618-24 |year= 2004 |pmid= 14506250 |doi= 10.1074/jbc.M309192200 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Cai Y |title=The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes |journal=J. Biol. Chem. |volume=280 |issue= 14 |pages= 13665–70 |year= 2005 |pmid= 15647280 |doi= 10.1074/jbc.M500001200  |name-list-format=vanc| author2=Jin J  | author3=Florens L  | display-authors=3  | last4=Swanson  | first4=SK  | last5=Kusch  | first5=T  | last6=Li  | first6=B  | last7=Workman  | first7=JL  | last8=Washburn  | first8=MP  | last9=Conaway  | first9=RC }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Ross MT |title=The DNA sequence of the human X chromosome |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440  | pmc=2665286  |name-list-format=vanc| author2=Grafham DV  | author3=Coffey AJ  | display-authors=3  | last4=Scherer  | first4=Steven  | last5=McLay  | first5=Kirsten  | last6=Muzny  | first6=Donna  | last7=Platzer  | first7=Matthias  | last8=Howell  | first8=Gareth R.  | last9=Burrows  | first9=Christine }}
*{{cite journal  | author=Cai Y, Jin J, Florens L, ''et al.'' |title=The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. |journal=J. Biol. Chem. |volume=280 |issue= 14 |pages= 13665-70 |year= 2005 |pmid= 15647280 |doi= 10.1074/jbc.M500001200 }}
*{{cite journal  | author=Ewing RM |title=Large-scale mapping of human protein–protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue=  1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134  | pmc=1847948  |name-list-format=vanc| author2=Chu P  | author3=Elisma F  | display-authors=3  | last4=Li  | first4=Hongyan  | last5=Taylor  | first5=Paul  | last6=Climie  | first6=Shane  | last7=McBroom-Cerajewski  | first7=Linda  | last8=Robinson  | first8=Mark D | last9=O'Connor | first9=Liam }}
*{{cite journal | author=Ross MT, Grafham DV, Coffey AJ, ''et al.'' |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325-37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 }}
*{{cite journal | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 06:45, 4 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Mortality factor 4-like protein 2 is a protein that in humans is encoded by the MORF4L2 gene.[1][2][3]


References

  1. ↑ Bertram MJ, Berube NG, Hang-Swanson X, Ran Q, Leung JK, Bryce S, Spurgers K, Bick RJ, Baldini A, Ning Y, Clark LJ, Parkinson EK, Barrett JC, Smith JR, Pereira-Smith OM (Feb 1999). "Identification of a Gene That Reverses the Immortal Phenotype of a Subset of Cells and Is a Member of a Novel Family of Transcription Factor-Like Genes". Mol Cell Biol. 19 (2): 1479–85. doi:10.1128/mcb.19.2.1479. PMC 116076. PMID 9891081.
  2. ↑ Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (Dec 1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1". DNA Res. 1 (1): 27–35. doi:10.1093/dnares/1.1.27. PMID 7584026.
  3. ↑ "Entrez Gene: MORF4L2 mortality factor 4 like 2".

Further reading



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