Liposarcoma staging: Difference between revisions

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==Overview==
==Overview==
The staging of liposarcoma is based on the TNM classification, which includes primary tumor spread, [[lymph node]] involvement, and presence of [[metastasis]].


==Staging==
==Staging==
{| style="border: 0px; font-size: 90%; margin: 3px; width: 500px;" align=center
{|
| valign=top |
{| style="border: 0px; font-size: 90%; margin: 3px; width: 350px;" align=center
|valign=top|
|valign=top|
|+
|+
! style="background: #4479BA;" colspan=2 | {{fontcolor|#FFF|Primary Tumor (T)}}
! style="background: #4479BA;" colspan=2 | {{fontcolor|#FFF|Primary Tumor (T)}}
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; width: 100px;"  |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; width: 50px;"  | Tx
| style="padding: 5px 5px; background: #F5F5F5;; width: 500px;" |  
| style="padding: 5px 5px; background: #F5F5F5;; width: 300px;" | Tumor cannot be assessed.
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;"|T0
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | No evidence of primary tumor.
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |T1
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" | Tumor ≤ 5 cm
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #F5F5F5;" |  
:T1a
| style="padding: 5px 5px; background: #F5F5F5;" | Superficial tumor <small>(not invading the fascia)</small>
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #F5F5F5;" |  
:T1b
| style="padding: 5px 5px; background: #F5F5F5;" | Deep tumor
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |T2
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | Tumor > 5 cm
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #F5F5F5;" |
:T2a
| style="padding: 5px 5px; background: #F5F5F5;" | Superficial tumor <small>(not invading the fascia)</small>
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #F5F5F5;" |  
:T2b
| style="padding: 5px 5px; background: #F5F5F5;" | Deep tumor
|-
|-
| style="padding: 5px 5px; background: #F5F5F5;" colspan=2|<small> Table adapted from National Cancer Institute <ref name="NCI"> {{cite web| url=http://www.cancer.gov/cancertopics/pdq/treatment/adult-soft-tissue-sarcoma/HealthProfessional/page3#Section_197| title= National Cancer Institute - Stage Information for Adult Soft Tissue Sarcoma}} </ref></small>
| style="padding: 5px 5px; background: #F5F5F5;" colspan=2|<small> Retrieved from the National Cancer Institute. Adapted from AJCC: Soft tissue sarcoma. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 291-8. <ref name="NCI"> {{cite web| url=http://www.cancer.gov/cancertopics/pdq/treatment/adult-soft-tissue-sarcoma/HealthProfessional/page3#Section_197| title= National Cancer Institute - Stage Information for Adult Soft Tissue Sarcoma}} </ref></small>
|}
|}
 
|
{| style="border: 0px; font-size: 90%; margin: 3px; width: 500px;" align=center
|valign=top|
{| style="border: 0px; font-size: 90%; margin: 3px; width: 350px;" align=center
|valign=top|
|valign=top|
|+
|+
! style="background: #4479BA;" colspan=2 | {{fontcolor|#FFF|Lymph Nodes (N)}}
! style="background: #4479BA;" colspan=2 | {{fontcolor|#FFF|Lymph Nodes (N)}}
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; width: 100px;"  |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; width: 50px;"  |NX
| style="padding: 5px 5px; background: #F5F5F5;; width: 500px;" |  
| style="padding: 5px 5px; background: #F5F5F5;; width: 300px;" | Lymph nodes cannot be assessed.
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |N0
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | No regional lymph node involvement.
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |N1
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |Regional lymph node involvement.
|-
|-
| style="padding: 5px 5px; background: #F5F5F5;" colspan=2|<small> Table adapted from National Cancer Institute <ref name="NCI"> {{cite web| url=http://www.cancer.gov/cancertopics/pdq/treatment/adult-soft-tissue-sarcoma/HealthProfessional/page3#Section_197| title= National Cancer Institute - Stage Information for Adult Soft Tissue Sarcoma}} </ref></small>
| style="padding: 5px 5px; background: #F5F5F5;" colspan=2|<small> Retrieved from the National Cancer Institute. Adapted from AJCC: Soft tissue sarcoma. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 291-8. <ref name="NCI"> {{cite web| url=http://www.cancer.gov/cancertopics/pdq/treatment/adult-soft-tissue-sarcoma/HealthProfessional/page3#Section_197| title= National Cancer Institute - Stage Information for Adult Soft Tissue Sarcoma}} </ref></small>
|}
|}
 
{| style="border: 0px; font-size: 90%; margin: 3px; width: 350px;" align=center
{| style="border: 0px; font-size: 90%; margin: 3px; width: 500px;" align=center
|valign=top|
|valign=top|
|+
|+
! style="background: #4479BA;" colspan=2 | {{fontcolor|#FFF|Metastasis (M)}}
! style="background: #4479BA;" colspan=2 | {{fontcolor|#FFF|Metastasis (M)}}
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; width: 100px;"  |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; width: 50px;"  | M0
| style="padding: 5px 5px; background: #F5F5F5;; width: 500px;" |  
| style="padding: 5px 5px; background: #F5F5F5;; width: 300px;" | No distant metastasis
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |M1
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | Distant metastasis
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #F5F5F5;" colspan=2|<small> Retrieved from the National Cancer Institute. Adapted from AJCC: Soft tissue sarcoma. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 291-8. <ref name="NCI"> {{cite web| url=http://www.cancer.gov/cancertopics/pdq/treatment/adult-soft-tissue-sarcoma/HealthProfessional/page3#Section_197| title= National Cancer Institute - Stage Information for Adult Soft Tissue Sarcoma}} </ref></small>
| style="padding: 5px 5px; background: #F5F5F5;" ||-
|}
| style="padding: 5px 5px; background: #F5F5F5;" colspan=2|<small> Table adapted from National Cancer Institute <ref name="NCI"> {{cite web| url=http://www.cancer.gov/cancertopics/pdq/treatment/adult-soft-tissue-sarcoma/HealthProfessional/page3#Section_197| title= National Cancer Institute - Stage Information for Adult Soft Tissue Sarcoma}} </ref></small>
|}
|}


{| style="border: 0px; font-size: 90%; margin: 3px; width: 700px;" align=center
|valign=top|
|+
| style="background: #4479BA; font-weight: bold; width: 100px;" | {{fontcolor|#FFF|Stages}}
| style="padding: 5px 5px; background: #4479BA; width: 100px;" | {{fontcolor|#FFF|Primary Tumor (T)}}
| style="padding: 5px 5px; background: #4479BA; width: 100px;" | {{fontcolor|#FFF|Lymph Node (N)}}
| style="padding: 5px 5px; background: #4479BA; width: 100px;" | {{fontcolor|#FFF|Metastasis (M)}}
| style="padding: 5px 5px; background: #4479BA; width: 100px;" | {{fontcolor|#FFF|Histopathological Grading}}
|-
| style="background: #4479BA; font-weight: bold; width: 100px;" | {{fontcolor|#FFF|Stage IA}}
| style="padding: 5px 5px; background: #DCDCDC; width: 100px;" | T1a, T1b
| style="padding: 5px 5px; background: #F5F5F5; width: 100px;" | N0
| style="padding: 5px 5px; background: #DCDCDC; width: 100px;" | M0
| style="padding: 5px 5px; background: #F5F5F5; width: 100px;" | Low grade
|-
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF|Stage IB}}
| style="padding: 5px 5px; background: #DCDCDC;" | T2a, T2b
| style="padding: 5px 5px; background: #F5F5F5;" | N0
| style="padding: 5px 5px; background: #DCDCDC;" | M0
| style="padding: 5px 5px; background: #F5F5F5;" | Low grade
|-
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF|Stage IIA}}
| style="padding: 5px 5px; background: #DCDCDC;" | T1a, T1b
| style="padding: 5px 5px; background: #F5F5F5;" | N0
| style="padding: 5px 5px; background: #DCDCDC;" | M0
| style="padding: 5px 5px; background: #F5F5F5;" | High grade
|-
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF| Stage IIB}}
| style="padding: 5px 5px; background: #DCDCDC;" | T2a, T2b
| style="padding: 5px 5px; background: #F5F5F5;" | N0
| style="padding: 5px 5px; background: #DCDCDC;" | M0
| style="padding: 5px 5px; background: #F5F5F5;" | High grade
|-
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF| Stage III}}
| style="padding: 5px 5px; background: #DCDCDC;" | Any T
| style="padding: 5px 5px; background: #F5F5F5;" | N0, N1
| style="padding: 5px 5px; background: #DCDCDC;" | M0
| style="padding: 5px 5px; background: #F5F5F5;" | High grade
|-
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF| Stage IV}}
| style="padding: 5px 5px; background: #DCDCDC;" | Any T
| style="padding: 5px 5px; background: #F5F5F5;" | Any N
| style="padding: 5px 5px; background: #DCDCDC;" | M1
| style="padding: 5px 5px; background: #F5F5F5;" | Any grade
|-
| style="padding: 5px 5px; background: #F5F5F5;" colspan=5|<small> Retrieved from the National Cancer Institute. Adapted from AJCC: Soft tissue sarcoma. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 291-8.<ref name="NCI"> {{cite web| url=http://www.cancer.gov/cancertopics/pdq/treatment/adult-soft-tissue-sarcoma/HealthProfessional/page3#Section_197| title= National Cancer Institute - Stage Information for Adult Soft Tissue Sarcoma}} </ref></small>
|}


==References==
==References==
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Latest revision as of 02:17, 27 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

The staging of liposarcoma is based on the TNM classification, which includes primary tumor spread, lymph node involvement, and presence of metastasis.

Staging
Primary Tumor (T)
Tx Tumor cannot be assessed.
T0 No evidence of primary tumor.
T1 Tumor ≤ 5 cm
T1a
 Superficial tumor (not invading the fascia)
T1b
 Deep tumor
T2 Tumor > 5 cm
T2a
 Superficial tumor (not invading the fascia)
T2b
 Deep tumor
Retrieved from the National Cancer Institute. Adapted from AJCC: Soft tissue sarcoma. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 291-8. [1]
Lymph Nodes (N)
NX Lymph nodes cannot be assessed.
N0 No regional lymph node involvement.
N1 Regional lymph node involvement.
Retrieved from the National Cancer Institute. Adapted from AJCC: Soft tissue sarcoma. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 291-8. [1]
Metastasis (M)
M0 No distant metastasis
M1 Distant metastasis
Retrieved from the National Cancer Institute. Adapted from AJCC: Soft tissue sarcoma. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 291-8. [1]
Stages Primary Tumor (T) Lymph Node (N) Metastasis (M) Histopathological Grading
Stage IA T1a, T1b N0 M0 Low grade
Stage IB T2a, T2b N0 M0 Low grade
Stage IIA T1a, T1b N0 M0 High grade
Stage IIB T2a, T2b N0 M0 High grade
Stage III Any T N0, N1 M0 High grade
Stage IV Any T Any N M1 Any grade
Retrieved from the National Cancer Institute. Adapted from AJCC: Soft tissue sarcoma. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 291-8.[1]

References

  1. ↑ 1.0 1.1 1.2 1.3 "National Cancer Institute - Stage Information for Adult Soft Tissue Sarcoma".


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